Results 291 to 300 of about 15,195 (308)
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Shedding microvesicles: artefacts no more
Trends in Cell Biology, 2009The small vesicles shed from the surface of many cells upon stimulation, considered for a long time to be artefacts, are now recognized as specific structures that are distinct from the exosomes released upon exocytosis of multivesicular bodies. Recent reports indicate that shedding vesicles participate in important biological processes, such as the ...
Emanuele Cocucci +2 more
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Microvesicles in Autoimmune Diseases
2016During apoptosis or activation, cells can release a subcellular structure, called a membrane microvesicle (also known as microparticle) into the extracellular environment. Microvesicles bud-off as a portion of cell membrane with its associated proteins and lipids surrounding a cytosolic core that contains intracellular proteins, lipids, and nucleic ...
Victoria P. Werth +3 more
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Microvesicles and pre-eclampsia
Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health, 2013The maternal syndrome of pre-eclampsia is characterised by an excessive inflammatory response associated with endothelial dysfunction, brought about by the release of multiple factors from the placenta into the maternal circulation. While some of these factors are released as soluble molecules it is now apparent that many of them are associated with ...
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Microvesicles and exosomes for intracardiac communication
Cardiovascular Research, 2014The heart is an organ with a complex mixture of well-organized interactions of different cell types that facilitate proper myocardial contractility, sufficient perfusion, balanced myocardial extracellular stiffness, and controlled functioning of the immune system.
Janine C. Deddens +4 more
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Proteins Regulating Microvesicle Biogenesis and Multidrug Resistance in Cancer
Proteomics, 2019Microvesicles (MV) are emerging as important mediators of intercellular communication. While MVs are important signaling vectors for many physiological processes, they are also implicated in cancer pathology and progression.
Jack Taylor, M. Bebawy
semanticscholar +1 more source
Blood/plasma secretome and microvesicles
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2013A major but hitherto overseen component of the blood/plasma secretome is that of extracellular vesicles (EVs) which are shed from all blood cell types. These EVs are made up of microvesicles (MVs) and exosomes. MVs, 100nm-1μm in diameter, are released from the cell surface, and are a rich source of non-conventionally secreted proteins lacking a ...
Sarah Azam +5 more
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The Role of Microvesicles in Malignancies
2011Microvesicles are membrane-covered cell fragments whose size varies between 30 and 1,000 nm. They are generated by all cell types, constituvely and in response to activation signals. Their importance in intercellular communication has been only recently discovered.
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Origami-paper-based device for microvesicle/exosome preconcentration and isolation.
Lab on a Chip, 2019Microvesicles and exosomes are promising liquid biopsy biomarkers. However, conventional isolation techniques damage and contaminate the biomarkers. We developed an origami-paper-based device for effective isolation of biomarkers with less damage and in ...
Hyerin Kim +6 more
semanticscholar +1 more source
Measurement of microvesicle levels in human blood using flow cytometry
Cytometry. Part B, Clinical cytometry, 2016Microvesicles are fragments of cells released when the cells are activated, injured, or apoptotic. Analysis of microvesicle levels in blood has the potential to shed new light on the pathophysiology of many diseases.
W. Chandler
semanticscholar +1 more source
Diabetes/Metabolism Research Reviews, 2017
To evaluate whether exposure to GLP‐1 receptor agonist Liraglutide could modulate pro‐atherogenic alterations previously observed in endothelial cells obtained by women affected by gestational diabetes (GD), thus exposed in vivo to hyperglycemia ...
P. Di Tomo +7 more
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To evaluate whether exposure to GLP‐1 receptor agonist Liraglutide could modulate pro‐atherogenic alterations previously observed in endothelial cells obtained by women affected by gestational diabetes (GD), thus exposed in vivo to hyperglycemia ...
P. Di Tomo +7 more
semanticscholar +1 more source