Results 121 to 130 of about 41,777 (311)

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

open access: yesJournal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag   +6 more
wiley   +1 more source

The Oral‐Hepatic Axis: Epidemiological and Mechanistic Links Between Periodontal and Liver Diseases

open access: yesJournal of Periodontal Research, EarlyView.
This review summarizes current epidemiological, clinical and mechanistic evidence linking periodontitis and chronic liver diseases, highlighting the oral‐gut‐liver axis, shared immunometabolic and nutritional pathways and opportunities for integrated preventive and therapeutic strategies.
Sinem Esra Sahingur   +3 more
wiley   +1 more source

Managing microvesicles or Virchow's vicissitude [PDF]

open access: yesThe Journal of Thoracic and Cardiovascular Surgery, 2022
Hunter, Moore, Alden, Harken
openaire   +2 more sources

Platelet‐activating factor‐receptor signaling mediates solar‐simulated light‐induced extracellular vesicle release in human keratinocytes

open access: yesPhotochemistry and Photobiology, EarlyView.
Solar‐simulated light (SSL) promotes extracellular vesicle (EV) release from keratinocytes through a UVB‐driven, oxidative stress‐dependent pathway. SSL‐induced reactive oxygen species (ROS) generate oxidized glycerophosphocholines with PAF agonistic activity, which activate the Platelet‐activating factor receptor (PAFR), leading to acid ...
Divyanshu Aggarwal   +3 more
wiley   +1 more source

Platelet-derived microvesicles isolated from type-2 diabetes mellitus patients harbour an altered miRNA signature and drive MDA-MB-231 triple-negative breast cancer cell invasion.

open access: yesPLoS ONE
The underlying causes of breast cancer are diverse, however, there is a striking association between type 2 diabetes and poor patient outcomes. Platelet activation is a common feature of both type 2 diabetes and breast cancer and has been implicated in ...
Anca Tutuianu   +7 more
doaj   +1 more source

Microvesicles as immune orchestra conductors

open access: yesBlood, 2008
In this issue of Blood, Sprague and colleagues report that platelet-derived membrane vesicles (PDMVs) orchestrate an immune response sufficient to deliver CD154 signals, which stimulate antigen-specific IgG production and modulate germinal-center formation, by cooperating with responses elucidated by CD4+ T cells.
openaire   +3 more sources

Understanding exosomes in diabetic wound healing

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Diabetic wounds signify a major complication of diabetes mellitus, characterized by chronic inflammation, compromised angiogenesis, and high risk of infection, amputation, and mortality. Contemporary therapies remain limited in efficacy and durability.
Paras Ahmad   +4 more
wiley   +1 more source

Understanding extracellular vesicle biology, isolation, and characterization: The theory of EV‐erything

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement.
Paras Ahmad   +6 more
wiley   +1 more source

Mass spec analysis of E14tg2a_4 microvesicles

open access: yes, 2015
A mass spectrometry analysis of E14tg2a.4 embryonic stem cell microvesicles.
Laura Desrochers (751882)   +2 more
core   +1 more source

Understanding extracellular vesicles in antiaging

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad   +3 more
wiley   +1 more source

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