Results 121 to 130 of about 32,107 (231)
Are calcifying microvesicles another analogous substructure of calcifying nanoparticles?
Trueman C Atughonu, Sateesh B Arja, Farooq A ShiekhAvalon University School of Medicine, Willemstad, CuracaoWe correspond in response to the article entitled, "Contrast-enhanced MR imaging of atherosclerosis using citrate-coated superparamagnetic iron ...
Atughonu TC, Arja SB, Shiekh FA
doaj
Graphical Abstract and Lay Summary Mesenchymal stem cells (MSCs) were cultured in standard, ultracentrifuged (UC), or starvation serum‐free media to evaluate how medium influences extracellular vesicle (EV) yield and purity. Culture in UC medium improved EV purity but reduced yield.
Jolene Phelps +3 more
wiley +1 more source
Exercise stimulates the release of extracellular vesicles from metabolically active tissues. These vesicles transport regulatory cargos, including microRNAs, proteins, lipids, and metabolites, to target organs such as skeletal muscle, adipose tissue, liver, and vascular tissues.
Jian Wang, Lei Wu
wiley +1 more source
Zielsetzung Dem Endothel wird eine zentrale Rolle in der Pathogenese des septischen Schocks zugeschrieben. Da bei diversen Erkrankungen, bei denen eine Mitbeteiligung des Endothels vorhanden ist, erhöhte Level endothelialer Mikrovesikel (MV) gefunden wurden, werden diese als Surrogatparameter angesehen, die den Zustand des Endothels widerspiegeln. Ziel
openaire +1 more source
Molecular Profiling of Extracellular Vesicles Isolated from Boar Reproductive Fluids
ABSTRACT Extracellular vesicles (EVs) are small membrane‐bound structures that facilitate intercellular communication in the reproductive system, modulating gamete maturation, capacitation, immunomodulation and fertilization. Despite pigs’ high relevance as a biomedical model, many aspects of EV biology remain poorly understood.
Veronika Kraus +9 more
wiley +1 more source
NDRG1 suppresses pancreatic cancer progression by disrupting small extracellular vesicle biogenesis, altering cargo composition, and inhibiting EV uptake by cancer cells—thereby impairing tumour–stroma communication and fibrotic activation. This study reveals NDRG1 as a novel regulator of extracellular vesicle dynamics and a promising therapeutic ...
Jiawei Chang +8 more
wiley +1 more source
Investigation Into the Collection and Isolation Workflows of Extracellular Vesicles From Tears
Sampling and isolation methodology shapes tear extracellular vesicle (tEV) composition, influencing housekeeping gene stability, tetraspanin expression, and cytokine levels. Contact lenses and Schirmer Strips provide complementary molecular signatures, while ExoQuick and ultracentrifugation differ in vesicle yield and surface properties.
Nikolay Boychev +4 more
wiley +1 more source
ABSTRACT Extracellular vesicles (EVs) are nanosized lipid bilayer particles naturally secreted by cells, mediating intercellular communication and transporting diverse bioactive molecules. Among alternative EV sources, bovine milk‐derived EVs (BMEVs) have emerged as promising platforms for drug delivery due to their accessibility, scalability ...
Martina Brattini +3 more
wiley +1 more source
Exosome Secretion Drives Chemo‐Resistance of Temozolomide in Glioblastoma
ABSTRACT Temozolomide (TMZ) is a first‐line chemotherapeutic agent for the treatment of glioblastoma (GBM), while a majority of patients do not effectively respond to TMZ owing to the multiple resistance mechanisms. In this study, we found that TMZ treatment substantially increased the exosome secretion from GBM cell line.
Wenpei Li +9 more
wiley +1 more source
Extracellular Vesicles in Head and Neck Cancer—A Systematic Review
ABSTRACT Head and neck cancer (HNC) is among the top ten malignancies worldwide and is associated with high morbidity and mortality. Oral potentially malignant disorders (OPMDs) predispose to certain HNCs. Recent studies suggest emerging roles of extracellular vesicles (EVs) in malignant transformation and provide potential in the management of HNC ...
Abdallah Swaid +5 more
wiley +1 more source

