Results 131 to 140 of about 55,239 (279)
International Journal of Dermatology, EarlyView.ABSTRACT Mesenchymal stromal cells (MSCs) exert their effects primarily through paracrine signaling via soluble factors and extracellular vesicles (EVs), especially exosomes. These acellular components offer regenerative and immunomodulatory benefits with fewer safety and logistical constraints than cell‐based therapies.
Marcela da Costa Pereira Cestari +2 more
wiley +1 more source
Roles of Microvesicles in Tumor Progression and Clinical Applications
International Journal of Nanomedicine, 2021 Shuangli Zhu,1 Shiyu Li,1 Ming Yi,1 Ning Li,2 Kongming Wu1,2 1Department of Oncology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, People’s Republic of China; 2Department of Medical Oncology ...
Zhu S, Li S, Yi M, Li N, Wu K
doaj
Megakaryocyte buds are distinct from microvesicles and likely to represent platelet precursors [PDF]
, 2022 Marc Ellis +4 more
openalex +1 more source
Managing microvesicles or Virchow's vicissitude [PDF]
The Journal of Thoracic and Cardiovascular Surgery, 2022 Hunter, Moore, Alden, Harken
openaire +2 more sources
Journal of Internal Medicine, EarlyView.Abstract The etiology of Alzheimer's disease (AD) remains under active debate. In this perspective, we explore the hypothesis that a primarily infection‐caused chronic dysregulation and weakening of human innate immunity via the underexpression, degradation, and inactivation of innate immune proteins necessary for direct antimicrobial effects and ...
Annelise E. Barron +3 more
wiley +1 more source
Journal of Periodontal Research, EarlyView.The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag +6 more
wiley +1 more source
Fibroblast growth factor-6 enhances CDK2 and MAKT expression in microvesicles derived from human stem cells extracted from exfoliated deciduous teeth [PDF]
, 2018 Ahmed Othman, Rabab Mubarak, Dina Sabry
openalex +1 more source
Photochemistry and Photobiology, EarlyView.Photodynamic therapy (PDT) is a nonscarring treatment modality that is widely used for skin cancers and early squamous precursor lesions. PDT was previously thought to work primarily by killing cancer cells directly (via apoptosis or necrosis). However, more recent work indicates that a significant mechanism for PDT is the stimulation of anti‐cancer ...
Mark P. Ortenzio +4 more
wiley +1 more source
Rapid Secretion of Interleukin-1β by Microvesicle Shedding [PDF]
, 2001 Amanda B. Mackenzie +5 more
openalex +1 more source
Photochemistry and Photobiology, EarlyView.In this model, ROS generated by UVB result in PAFR agonists acting upon the PAFR resulting in MVP generation release via the enzyme aSMase. In photosensitivity, there are increased ROS, resulting in augmented PAF agonists and increased MVP release. This process can be blocked by aSMase inhibitors.
Risha Annamraju +13 more
wiley +1 more source