Results 161 to 170 of about 41,777 (311)

ALY688 Protects Against Myocardial Ischemia‐Reperfusion Injury via Direct Effects and Rab8a‐Dependent Extracellular Vesicles

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.
This study identifies ALY688, a synthetic adiponectin receptor agonist, as a potent cardioprotective agent against ischemia‐reperfusion injury. ALY688 reduced infarct size, cardiomyocyte death, and oxidative stress, while preserving cardiac function. Mechanistically, it enhanced extracellular vesicle (EV) number through Rab8a‐dependent signaling and ...
Hye Kyoung Sung   +12 more
wiley   +1 more source

Regenerative strategies for ALS: stem cells and extracellular vesicles. [PDF]

open access: yesDiscov Nano
Raghunathan T   +4 more
europepmc   +1 more source

Bovine Colostrum‐Derived Extracellular Vesicles Impair Cancer Cell Proliferation Through Transcriptional Dysregulation

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.
ABSTRACT Milk‐derived extracellular vesicles (EVs) are a promising source of molecules with therapeutic potential. Bovine colostrum is particularly enriched in EVs, which carry cargo of proteins involved in immune regulation, development and cellular signalling.
Claudia Betsabé Huesa‐Carballo   +11 more
wiley   +1 more source

Microvesicles in sepsis

open access: yes, 2018
Zielsetzung Dem Endothel wird eine zentrale Rolle in der Pathogenese des septischen Schocks zugeschrieben. Da bei diversen Erkrankungen, bei denen eine Mitbeteiligung des Endothels vorhanden ist, erhöhte Level endothelialer Mikrovesikel (MV) gefunden wurden, werden diese als Surrogatparameter angesehen, die den Zustand des Endothels widerspiegeln. Ziel
openaire   +1 more source

Neuronal Apoptotic Bodies Facilitate Japanese Encephalitis Virus Infection and Pathogenicity

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.
ABSTRACT Japanese encephalitis (JE) caused by Japanese encephalitis virus (JEV) infection remains one of the major types of viral encephalitis. The mechanisms underlying JEV infection and pathogenesis have not been fully elucidated, resulting in the absence of specific therapies for JE. Neuronal apoptosis is a well‐established outcome of JEV infection;
Chuan Zeng   +9 more
wiley   +1 more source

GW4869 Depletes Macrophages and Increases Number of Extracellular Vesicles in Murine Peritoneal Cavity Fluid

open access: yesJournal of Extracellular Biology, Volume 5, Issue 9, September 2026.
ABSTRACT Pharmacological strategies to modulate extracellular vesicle (EV) release in vivo are gaining traction, yet their broader effects on local immune microenvironments remain unclear. In this study, we assessed how repeated intraperitoneal (i.p.) dosing of the neutral sphingomyelinase inhibitor GW4869 reshapes the peritoneal cavity.
Johann Mar Gudbergsson   +3 more
wiley   +1 more source

Snakebites and microvesicles: Popping bubbles [PDF]

open access: yesResearch and Practice in Thrombosis and Haemostasis, 2019
Bos, M.H.A., Versteeg, H.H.
openaire   +3 more sources

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