ABSTRACT Recent studies have shown that adipose tissue (AT) secretes elevated levels of extracellular vesicles (EVs) in obesity, and these EVs play roles in metabolic diseases. The inhibition of calpains has anti‐inflammatory and anti‐fibrotic effects on AT in mice and reduces EV secretion in some cell types in vitro.
Johanna Matilainen +18 more
wiley +1 more source
Role of Microvesicles in reproductive diseases, especially in polycystic ovary syndrome.
Paola Briseño-Díaz
openalex +1 more source
This study evaluated 11 extracellular vesicle (EV) isolation methods which generate plasma‐derived EV‐containing preparations with varying degrees of contaminants. No single approach optimized purity and proteome coverage. In this paper we use proteomics to present an Evidence‐Based Framework to select plasma EV isolation methods based on downstream ...
Scheila Julia Werle +5 more
wiley +1 more source
Kinetics and characterization of extracellular vesicle release from cells infected with a clinical isolate of respiratory syncytial virus A (ON1 genotype). [PDF]
Fracella M +11 more
europepmc +1 more source
Comparative Assessment of Methods for Isolation and Imaging of Extracellular Vesicles
Isolation and characterization of human mesenchymal stromal cell extracellular vesicles with ultracentrifugation and lacey carbon TEM grid preparations provide a greater preservation of morphology and the opportunity to validate dynamic light scattering for size distribution measurement of EVs derived from clonal and polyclonal hMSC samples.
Edward Carson +8 more
wiley +1 more source
Quantitative Analysis of Pulmonary Right-to-Left Shunts and Patent Foramen Ovale via Agitated Saline Contrast Transesophageal Echocardiography: Associations With Migraine, Cryptogenic Stroke, and Transient Ischemic Attack. [PDF]
Chen J +5 more
europepmc +1 more source
Isolation, characterization, and proteomic analysis of plasma-derived exosomes and microvesicles in Parkinson’s disease v1 [PDF]
Wenzheng Hu +7 more
openalex +1 more source
ABSTRACT The notochord is a central signalling hub during embryonic development. After regression of the notochord, notochordal cells (NCs) reside within the developing intervertebral disc. The NC‐secretome, including matrix, proteins and extracellular vesicles (NC‐EVs), promotes regeneration of degenerate intervertebral discs and cartilage. This study
Josette C. van Maanen +14 more
wiley +1 more source
Created with BioRender.com. ABSTRACT Extracellular vesicles (EVs) are widely studied as mediators of intercellular communication, yet their quantitative characterization remains inconsistent. In this study, we investigated how vesicle release rate, cellular proliferation, and tumour origin jointly shape EV‐associated protein output. Using a panel of 19
Tímea Böröczky +9 more
wiley +1 more source
Sustained low micromolar hydrogen peroxide exposure induces sequential red blood cell dysfunction. [PDF]
Baek JH +4 more
europepmc +1 more source

