Results 171 to 180 of about 41,777 (311)

Calpeptin Reduces Extracellular Vesicle Secretion and Induces Anti‐Inflammatory Effects but Upregulates HO‐1 and Alters Adiponectin Levels in Human Adipocytes

open access: yesJournal of Extracellular Biology, Volume 5, Issue 9, September 2026.
ABSTRACT Recent studies have shown that adipose tissue (AT) secretes elevated levels of extracellular vesicles (EVs) in obesity, and these EVs play roles in metabolic diseases. The inhibition of calpains has anti‐inflammatory and anti‐fibrotic effects on AT in mice and reduces EV secretion in some cell types in vitro.
Johanna Matilainen   +18 more
wiley   +1 more source

Method Matters: A Proteomics‐Informed Framework for Selecting Extracellular Vesicle Isolation Methods for Plasma

open access: yesJournal of Extracellular Biology, Volume 5, Issue 9, September 2026.
This study evaluated 11 extracellular vesicle (EV) isolation methods which generate plasma‐derived EV‐containing preparations with varying degrees of contaminants. No single approach optimized purity and proteome coverage. In this paper we use proteomics to present an Evidence‐Based Framework to select plasma EV isolation methods based on downstream ...
Scheila Julia Werle   +5 more
wiley   +1 more source

Kinetics and characterization of extracellular vesicle release from cells infected with a clinical isolate of respiratory syncytial virus A (ON1 genotype). [PDF]

open access: yesMed Microbiol Immunol
Fracella M   +11 more
europepmc   +1 more source

Comparative Assessment of Methods for Isolation and Imaging of Extracellular Vesicles

open access: yesJournal of Extracellular Biology, Volume 5, Issue 9, September 2026.
Isolation and characterization of human mesenchymal stromal cell extracellular vesicles with ultracentrifugation and lacey carbon TEM grid preparations provide a greater preservation of morphology and the opportunity to validate dynamic light scattering for size distribution measurement of EVs derived from clonal and polyclonal hMSC samples.
Edward Carson   +8 more
wiley   +1 more source

Isolation, characterization, and proteomic analysis of plasma-derived exosomes and microvesicles in Parkinson’s disease v1 [PDF]

open access: gold
Wenzheng Hu   +7 more
openalex   +1 more source

Proteomic Atlas of Notochordal Cell‐Derived Extracellular Vesicles Highlights EV‐Specific NF‐κB Modulation and Functional Implications of the Protein Corona

open access: yesJournal of Extracellular Biology, Volume 5, Issue 9, September 2026.
ABSTRACT The notochord is a central signalling hub during embryonic development. After regression of the notochord, notochordal cells (NCs) reside within the developing intervertebral disc. The NC‐secretome, including matrix, proteins and extracellular vesicles (NC‐EVs), promotes regeneration of degenerate intervertebral discs and cartilage. This study
Josette C. van Maanen   +14 more
wiley   +1 more source

When EV Dose Is Not What It Seems: Quantitative Mismatch Between Particle Number‐ and Protein‐Based Dosing

open access: yesJournal of Extracellular Biology, Volume 5, Issue 9, September 2026.
Created with BioRender.com. ABSTRACT Extracellular vesicles (EVs) are widely studied as mediators of intercellular communication, yet their quantitative characterization remains inconsistent. In this study, we investigated how vesicle release rate, cellular proliferation, and tumour origin jointly shape EV‐associated protein output. Using a panel of 19
Tímea Böröczky   +9 more
wiley   +1 more source

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