Results 181 to 190 of about 53,120 (272)

Extracellular Vesicles in Osteoarthritis: From Pathogenic Mediators to Engineered Therapeutics in a Precision Medicine Roadmap

open access: yesJournal of Extracellular Biology, Volume 5, Issue 5, May 2026.
ABSTRACT Osteoarthritis (OA) remains without disease‐modifying sssstherapies, in part due to biological heterogeneity and a hostile joint microenvironment that undermines one‐size‐fits‐all interventions. Extracellular vesicles (EVs) play a dual role in OA pathophysiology: endogenous EVs disseminate pro‐inflammatory and catabolic signals that propagate ...
Duc‐Hiep Bach   +2 more
wiley   +1 more source

Exercise and Skeletal Muscle‐Derived Extracellular Vesicles: Their Cargo, Release, and Role in Metabolic Regulation

open access: yesJournal of Extracellular Biology, Volume 5, Issue 5, May 2026.
ABSTRACT The health benefits of exercise are well established in the prevention and management of metabolic disorders such as obesity and diabetes. Emerging evidence indicates that extracellular vesicles (EVs) may contribute to the beneficial effects of exercise.
Jeremy Boulestreau   +3 more
wiley   +1 more source

Flow Cytometric Detection of Biomarker Changes in CFDA‐SE‐Labelled Plasma Extracellular Vesicles Using a Rodent Pregnancy Model of Prenatal Diagnostics

open access: yesJournal of Extracellular Biology, Volume 5, Issue 5, May 2026.
ABSTRACT Circulating extracellular vesicles (EVs) offer a promising source of non‐invasive biomarkers for congenital disease diagnostics but robust assays for their detection are lacking. We used a rodent pregnancy model as a proxy for a prenatal diagnostics assay to test whether we could detect a difference in EV tetraspanin display between pregnant ...
Petra Adamova   +3 more
wiley   +1 more source

Targeting Tumor Stroma: Current Challenges and Future Directions

open access: yesMedComm, Volume 7, Issue 5, May 2026.
Figure 1. Mechanism of ECM reprogramming. Cancer‐associated fibroblasts (CAFs), cancer‐associated macrophages (CAMs), and other mesenchymal cells alter the ECM composition and increase its stiffness by depositing matrix components such as collagen and hyaluronic acid, and secreting cross‐linking agents like lysyl oxidase homolog 2 (LOXL2).
Siwei Wang   +7 more
wiley   +1 more source

Mitochondrial Transfer in the Tumor Microenvironment

open access: yesCancer Science, Volume 117, Issue 5, Page 1189-1198, May 2026.
Mitochondria are actively exchanged among tumor, immune, stromal, and neuronal cells within the tumor microenvironment. Such transfer rewires tumor metabolism, promotes immune evasion, and drives therapy resistance. Targeting mitochondrial transfer or harnessing mitochondrial transplantation represents a promising strategy to restore antitumor immunity
Ryo Omae   +2 more
wiley   +1 more source

Under Pressure: Rapid Infusion of Stored Whole Blood Alters Coagulation Parameters. [PDF]

open access: yesJ Surg Res
Becker ER   +6 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy