Multifunctional Applications of Extracellular Nanovesicles for Acute Kidney Injury and Renal Fibrosis; a Mini Review. [PDF]
Xu R, Liu S, Cui Z.
europepmc +1 more source
ABSTRACT Osteoarthritis (OA) remains without disease‐modifying sssstherapies, in part due to biological heterogeneity and a hostile joint microenvironment that undermines one‐size‐fits‐all interventions. Extracellular vesicles (EVs) play a dual role in OA pathophysiology: endogenous EVs disseminate pro‐inflammatory and catabolic signals that propagate ...
Duc‐Hiep Bach +2 more
wiley +1 more source
Autographa californica multiple nucleopolyhedrovirus <i>e18</i> is essential for the formation of normal intranuclear membrane microvesicles and intranuclear envelopment and nuclear egress of nucleocapsids. [PDF]
Wang L, Zhou X, Zhao X, Zeng X, Li L-L.
europepmc +1 more source
ABSTRACT The health benefits of exercise are well established in the prevention and management of metabolic disorders such as obesity and diabetes. Emerging evidence indicates that extracellular vesicles (EVs) may contribute to the beneficial effects of exercise.
Jeremy Boulestreau +3 more
wiley +1 more source
ABSTRACT Circulating extracellular vesicles (EVs) offer a promising source of non‐invasive biomarkers for congenital disease diagnostics but robust assays for their detection are lacking. We used a rodent pregnancy model as a proxy for a prenatal diagnostics assay to test whether we could detect a difference in EV tetraspanin display between pregnant ...
Petra Adamova +3 more
wiley +1 more source
Sub-Neuronal Network Profiling of Extracellular Vesicle Release Using a Compartmentalized Neurofluidic Platform. [PDF]
Malkoc Z +4 more
europepmc +1 more source
Targeting Tumor Stroma: Current Challenges and Future Directions
Figure 1. Mechanism of ECM reprogramming. Cancer‐associated fibroblasts (CAFs), cancer‐associated macrophages (CAMs), and other mesenchymal cells alter the ECM composition and increase its stiffness by depositing matrix components such as collagen and hyaluronic acid, and secreting cross‐linking agents like lysyl oxidase homolog 2 (LOXL2).
Siwei Wang +7 more
wiley +1 more source
Mitochondria-Derived Vesicles and Mitochondrial Extracellular Vesicles in Health and Cardiovascular Disease. [PDF]
Rapushi E +5 more
europepmc +1 more source
Mitochondrial Transfer in the Tumor Microenvironment
Mitochondria are actively exchanged among tumor, immune, stromal, and neuronal cells within the tumor microenvironment. Such transfer rewires tumor metabolism, promotes immune evasion, and drives therapy resistance. Targeting mitochondrial transfer or harnessing mitochondrial transplantation represents a promising strategy to restore antitumor immunity
Ryo Omae +2 more
wiley +1 more source
Under Pressure: Rapid Infusion of Stored Whole Blood Alters Coagulation Parameters. [PDF]
Becker ER +6 more
europepmc +1 more source

