Results 211 to 220 of about 59,785 (337)

Extracellular vesicles from adipose‐derived mesenchymal stem cells prevent high glucose‐induced retinal ganglion cell pyroptosis through a microRNA‐26a‐5p‐dependent mechanism

Journal of Diabetes Investigation, EarlyView.
ADSC‐EVs carrying miR‐26a‐5p confer protection against RGC pyroptosis by targeting HDAC4 and activating H3K27ac‐dependent Nrf2 expression. ABSTRACT Objective Mesenchymal stromal/stem cells have neuroprotective effects that limit damage to the retina, which is predominantly mediated by the released extracellular vesicles (EVs).
Lei Tang, Jian Zhang, Jianping Gao
wiley   +1 more source

Is Adipose Tissue Inflammation the Culprit of Obesity‐Associated Comorbidities?

Obesity Reviews, EarlyView.
ABSTRACT In individuals with obesity, the onset of chronic comorbidities coincides with the excessive accumulation of adipose tissue in various tissue beds. As obesity progresses, adipose tissue becomes increasingly dysfunctional causing chronic low‐grade inflammation.
Laurent Turner, Anjalee I. Wanasinghe, Pamela Brunori, Sylvia Santosa   +3 more
wiley   +1 more source

Immunomodulatory effects of photodynamic therapy for skin cancer: Potential strategies to improve treatment efficacy and tolerability

Photochemistry and Photobiology, EarlyView.
Photodynamic therapy (PDT) is a nonscarring treatment modality that is widely used for skin cancers and early squamous precursor lesions. PDT was previously thought to work primarily by killing cancer cells directly (via apoptosis or necrosis). However, more recent work indicates that a significant mechanism for PDT is the stimulation of anti‐cancer ...
Mark P. Ortenzio, Sanjay Anand, Jeffrey B. Travers, Edward V. Maytin, Craig A. Rohan   +4 more
wiley   +1 more source

Are calcifying microvesicles another analogous substructure of calcifying nanoparticles?

International Journal of Nanomedicine, 2013
Trueman C Atughonu, Sateesh B Arja, Farooq A ShiekhAvalon University School of Medicine, Willemstad, CuracaoWe correspond in response to the article entitled, "Contrast-enhanced MR imaging of atherosclerosis using citrate-coated superparamagnetic iron ...
Atughonu TC, Arja SB, Shiekh FA
doaj  

Induction of Lymphocyte Apoptosis by Tumor Cell Secretion of FasL-bearing Microvesicles

, 2002
Giovanna Andreola, Licia Rivoltini, Chiara Castelli, Veronica Huber, Paola Perego, Paola Deho, Paola Squarcina, Paola Accornero, Francesco Lozupone, Luana Lugini, Annarita Stringaro, Agnese Molinari, Giuseppe Arancia, Massimo Gentile, Giorgio Parmiani, Stefano Fais   +15 more
openalex   +1 more source

Microfluidic isolation and transcriptome analysis of serum microvesicles [PDF]

, 2009
Chihchen Chen, Johan Skog, Chia‐Hsien Hsu, Ryan Lessard, Leonora Balaj, Thomas Würdinger, Bob S. Carter, Xandra O. Breakefield, Mehmet Toner, Daniel Irimia   +9 more
openalex   +1 more source

The impact of pressure and temperature on the quality of suspended red blood cells: An ex vivo simulation study

Transfusion Medicine, EarlyView.
Abstract Objective This study aims to explore the impact of pressurisation and simultaneous warming at a combination of 50 kPa and 46°C on the quality of suspended red blood cells in an ex vivo environment. Background During massive rapid blood transfusion, pressure and temperature‐controlled blood warming devices are often used to prevent hypothermia ...
Chunyu Feng, Rui Fan, Haimei Ma, Huan Zhang   +3 more
wiley   +1 more source

Technical considerations and review of urinary microRNAs as biomarkers for chronic kidney disease in dogs and cats

Veterinary Clinical Pathology, EarlyView.
Abstract MicroRNAs (miRNAs or miRs) are small, non‐coding RNAs that play a crucial role in gene regulation, making them potential biomarkers for various diseases. In the field of veterinary medicine, there is a growing interest in exploring the diagnostic and therapeutic potential of miRNAs in kidney diseases affecting dogs and cats.
Candice P. Chu, Mary B. Nabity
wiley   +1 more source

Differential intestinal injury and unchanged systemic inflammatory responses to leg and whole‐body passive hyperthermia in healthy humans

Experimental Physiology, EarlyView.
Abstract Hyperthermia can cause intestinal injury, facilitating endotoxin translocation and an inflammatory response that has been associated with heat illness. However, the potential occurrence of these responses has been incompletely reported during passive hyperthermia, and the independent effect of hyperthermia is equivocal.
Oliver R. Gibson, Orlando Laitano, Kazuhito Watanabe, José González‐Alonso   +3 more
wiley   +1 more source

Therapeutic and diagnostic applications of extracellular vesicles [PDF]

, 2016
De Smedt, Stefaan, Raemdonck, Koen, Stremersch, Stephan   +2 more
core   +1 more source