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Apoptotic vesicles in cancer: research progress in physiology and therapy. [PDF]
Dai J +6 more
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Tranexamic acid impairs plasmin generation on human mesenchymal stem cells and derived membrane microvesicles, halting pericellular proteolysis. [PDF]
Abou Rjeily R +5 more
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Mechanobiology of microvesicle release, uptake, and microvesicle-mediated activation
2020Microvesicles are small, membrane-bound vesicles that are shed from the plasma membrane of cells into the extracellular space. Microvesicles contain a variety of cargo not typically thought to be released from cells, including receptor tyrosine kinases, cytosolic signaling proteins, and microRNAs, which are transferred from donor cells to recipient ...
Samantha C, Schwager +1 more
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Tumor-derived microvesicles: The metastasomes
Medical Hypotheses, 2013Metastasis is the leading cause of cancer death, yet it is mechanistically considered a very inefficient process suggesting the presence of some sort of (e.g. systemic) routes for fuelling the process. The pre-metastatic niche formation is described as one such metastasis promoting route.
Ghasemi R +6 more
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Microvesicles in Autoimmune Diseases
2016During apoptosis or activation, cells can release a subcellular structure, called a membrane microvesicle (also known as microparticle) into the extracellular environment. Microvesicles bud-off as a portion of cell membrane with its associated proteins and lipids surrounding a cytosolic core that contains intracellular proteins, lipids, and nucleic ...
M-L, Liu, K J, Williams, V P, Werth
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Shedding microvesicles: artefacts no more
Trends in Cell Biology, 2009The small vesicles shed from the surface of many cells upon stimulation, considered for a long time to be artefacts, are now recognized as specific structures that are distinct from the exosomes released upon exocytosis of multivesicular bodies. Recent reports indicate that shedding vesicles participate in important biological processes, such as the ...
Emanuele, Cocucci +2 more
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Microvesicles and pre-eclampsia
Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health, 2013The maternal syndrome of pre-eclampsia is characterised by an excessive inflammatory response associated with endothelial dysfunction, brought about by the release of multiple factors from the placenta into the maternal circulation. While some of these factors are released as soluble molecules it is now apparent that many of them are associated with ...
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