Results 241 to 250 of about 63,152 (354)
This review explores the role of metabolic reprogramming in inflammatory bowel disease (IBD) by focusing on immune and epithelial cell metabolism, microbial metabolites, and their impact on inflammation. It discusses emerging metabolic therapies and emphasizes the importance of personalized microbiota‐targeted approaches to improve clinical outcomes in
Zemin Tian +6 more
wiley +1 more source
Assessment of frailty in patients with advanced chronic kidney disease, and the role of microvesicles: A single-center study. [PDF]
Gimena Muñoz R +9 more
europepmc +1 more source
Lactadherin and clearance of platelet-derived microvesicles [PDF]
Swapan Dasgupta +8 more
openalex +1 more source
Extracellular vesicle‐based vaccines and immunotherapeutics for treatment of cancer
This review highlights the innovative value of extracellular vesicles (EVs) as cancer vaccines and immunotherapy carriers. EVs have natural advantages such as low immunogenicity, high biocompatibility, stability, and precise targeting, enabling efficient delivery of tumor antigens (e.g., HER2, AFP) and immune stimulants (e.g., TLR ligands, cytokines ...
Lejia Tan +4 more
wiley +1 more source
Extracellular Vesicle microRNAs in the Crosstalk Between Cancer Cells and Natural Killer (NK) Cells. [PDF]
Toldo N, Wu Y, Fabbri M.
europepmc +1 more source
Cholesterol Deficiency Directs Autophagy‐Dependent Secretion of Extracellular Vesicles
Inhibition of cholesterol biosynthesis within models of rare disease and cancer causes increased release of small extracellular vesicles (sEVs) with distinct biological properties. Mechanistically, cholesterol depletion leads to impaired autophagic flux, redirection of autophagosomes to late endosomes, and subsequently increased sEV secretion ...
Jazmine D. W. Yaeger +6 more
wiley +1 more source
Extracellular Vesicles as Emerging Regulators in Ischemic and Hypertrophic Cardiovascular Diseases: A Review of Pathogenesis and Therapeutics. [PDF]
Chen M, Wu Y, Chen C.
europepmc +1 more source
ABSTRACT Idiopathic pulmonary fibrosis (IPF) is a fatal fibrotic lung disease characterized by aberrant myofibroblast activation and excessive extracellular matrix deposition, with extracellular vesicles (EVs) playing a crucial role in this pathological process. We observed that EVs levels are significantly elevated in IPF and positively correlate with
Xiaofan Lai +14 more
wiley +1 more source
TGF-β2 increases eHSP90α secretion via upregulating secretory autophagy pathway. [PDF]
Li J +16 more
europepmc +1 more source

