Results 81 to 90 of about 41,777 (311)
EBioMedicine, 2019 Background: The complement and kallikrein-kinin systems (KKS) are activated during vascular inflammation. The aim of this study was to investigate if blockade of the KKS can affect complement activation on the endothelium during inflammation.
Ingrid Lopatko Fagerström +10 more
doaj +1 more source
Circulating Microvesicles in Regenerative Angiogenesis [PDF]
Current Trends in Biomedical Engineering & Biosciences, 2017 Extracellular microvesicles (EVs) released by different cells have been shown to facilitate the transfer of several pro-angiogenic as well as anti-antigenic factors that can regulate gene expression in endothelial cells. Our recent study has demonstrated that the profiles of cytokines and angiogenic-active factors in EVs are significantly changed in ...
Drożdż, Anna, Stępień, Ewa
openaire +2 more sources
ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia +2 more
wiley +1 more source
Thromboinflammatory effects of RBC microvesicles [PDF]
Blood, 2020 In this issue of Blood, Noubouossie et al provide new insights into potential mechanisms for thromboinflammatory complications associated with red blood cell (RBC) transfusions. By using leukoreduced RBC units to isolate RBC microvesicles (RBC-MVs), they document that RBC-MVs activate factor IX (FIX) via 2 distinct pathways: (1) the canonical ...
openaire +2 more sources
Structural characterization of platelets and platelet microvesicles [PDF]
, 2016 © 2016, Pleiades Publishing, Ltd.Platelets are blood cells without nuclei, which, in conjunction with fibrin, cause bleeding to stop (hemostasis). Cellular microvesicles are microscopic particles released into extracellular space under activation and/or ...
Mordakhanova E. +4 more
core
trans-Sialidase is shed in microvesicles.
, 2016 Western blots of microvesicles purified by two independent methods, Exoquick kit (A) and ultracentrifugation (B), show TS presence only in the microvesicles fraction. Mucins were found predominantly in microvesicles although also to a minor extent in the
Juan Mucci (190574) +11 more
core +1 more source
Review of articular cartilage repair techniques and their application in the horse
Equine Veterinary Journal, EarlyView.Abstract Articular cartilage lesions represent a significant career‐limiting problem in athletic horses. A healthy articular cartilage surface is vital for optimal joint function, and defects can result in irreversible degenerative changes. Successful treatment of cartilage lesions remains a long‐standing challenge for orthopaedic surgeons, prompting ...
Charlotte K. Barton +2 more
wiley +1 more source
Interdisciplinary Medicine, EarlyView.The graphical abstract outlines a novel multifunctional ultrasound contrast agent for the diagnosis and treatment of ischemic diseases, along with innovative strategies to enhance its targeting efficiency. Abstract Ischemic diseases, such as myocardial infarction, stroke, and peripheral ischemia, are leading causes of death and disability worldwide ...
Yangyang Zhou +3 more
wiley +1 more source
Fluids and Barriers of the CNS, 2013 Background In addition to possessing intracellular vesicles, eukaryotic cells also produce extracellular microvesicles, ranging from 50 to 1000 nm in diameter that are released or shed into the microenvironment under physiological and pathological ...
Haqqani Arsalan S +5 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2020 Shiga toxin is the main virulence factor of non-invasive enterohemorrhagic Escherichia coli strains capable of causing hemolytic uremic syndrome. Our group has previously shown that the toxin can reach the kidney within microvesicles where it is taken up
Karl Johansson +6 more
doaj +1 more source