Results 71 to 80 of about 32,107 (231)

Endothelial Microvesicles and Soluble Markers of Endothelial Injury in Critically Ill Newborns

open access: yesMediators of Inflammation, 2018
Neonatal systemic inflammatory response and multiple organ dysfunction syndrome are the main postnatal insults influencing mortality and morbidity. Critically ill newborns with high predicted mortality are supported by extracorporeal membrane oxygenation
Veronika Vítková   +7 more
doaj   +1 more source

Review of articular cartilage repair techniques and their application in the horse

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Articular cartilage lesions represent a significant career‐limiting problem in athletic horses. A healthy articular cartilage surface is vital for optimal joint function, and defects can result in irreversible degenerative changes. Successful treatment of cartilage lesions remains a long‐standing challenge for orthopaedic surgeons, prompting ...
Charlotte K. Barton   +2 more
wiley   +1 more source

Method for isolation and molecular characterization of extracellular microvesicles released from brain endothelial cells

open access: yesFluids and Barriers of the CNS, 2013
Background In addition to possessing intracellular vesicles, eukaryotic cells also produce extracellular microvesicles, ranging from 50 to 1000 nm in diameter that are released or shed into the microenvironment under physiological and pathological ...
Haqqani Arsalan S   +5 more
doaj   +1 more source

Microvesicles in disease

open access: yes, 2014
On activation cells shed vesicles from their surface by the process of ectocytosis. These micro-vesicles or Ectosomes express phosphatidyl-serine (PS) on their surface, which can elicit a range of biological effects from immune-suppression to the activation of the clotting and complement pathways.
openaire   +2 more sources

CCL26‐Mediated Modulation of Endothelial Secretome by Hypoxia‐Induced Tumor‐Derived Exosomes Enhances Metastatic Progression in Head and Neck Cancer

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Tumor cells adapt to hypoxia by releasing hiTDExs enriched with bioactive molecules that modulate endothelial behavior and promote tumor progression. This study aimed to characterize how hypoxia‐induced HNSCC exosomes reshape the endothelial secretome and contribute to metastatic potential.
Ozel Capik   +6 more
wiley   +1 more source

Sleep deprivation aggravates hepatocytes steatosis and insulin resistance by regulating exosomal microRNAs

open access: yesInterdisciplinary Medicine, EarlyView.
Sleep deprivation accelerates the progression of MASLD and IR by up‐regulating the expression of miR‐3572‐5p and down‐regulating the expression of miR‐183‐5p in circulating exosomes, thereby inhibiting fatty acid β‐oxidation and disrupting insulin signaling pathways. Abstract Sleep deprivation (SD) threatens human health and increases the prevalence of 
Xinxin Xu   +10 more
wiley   +1 more source

Shiga Toxin-Bearing Microvesicles Exert a Cytotoxic Effect on Recipient Cells Only When the Cells Express the Toxin Receptor

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
Shiga toxin is the main virulence factor of non-invasive enterohemorrhagic Escherichia coli strains capable of causing hemolytic uremic syndrome. Our group has previously shown that the toxin can reach the kidney within microvesicles where it is taken up
Karl Johansson   +6 more
doaj   +1 more source

Attack of the microvesicles

open access: yesThe Journal of Cell Biology, 2002
![Graphic][1] Melanoma cells can attack using microvesicles loaded with FasL (red). Fais/RUPMelanoma cells send out microvesicles loaded with Fas ligand (FasL) to kill their would-be assassins, according to Stefano Fais (Istituto Superiore di Sanita, Rome, Italy), Licia Rivoltini (
openaire   +2 more sources

A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside

open access: yesInterdisciplinary Medicine, EarlyView.
This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione   +2 more
wiley   +1 more source

Hydrous Carbonatitic Liquids Drive CO2 Recycling From Subducted Marls and Limestones

open access: yesGeophysical Monograph Series, Page 209-221., 2020

This book is Open Access. A digital copy can be downloaded for free from Wiley Online Library.

Explores the behavior of carbon in minerals, melts, and fluids under extreme conditions

Carbon trapped in diamonds and carbonate-bearing rocks in subduction zones are examples of the continuing exchange of substantial carbon ...
Erwin Schettino, Stefano Poli
wiley  

+1 more source

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