Results 101 to 110 of about 136,839 (238)

Intramuscular midazolam versus intravenous lorazepam for the prehospital treatment of status epilepticus in the pediatric population

Epilepsia, 2015
To examine the effectiveness of intramuscular (IM) midazolam versus intravenous (IV) lorazepam for the treatment of pediatric patients with status epilepticus (SE) in the prehospital care setting.
R. Welch, Katherine S. Nicholas, Valerie L. Durkalski-Mauldin, D. Lowenstein, R. Conwit, Prashant V. Mahajan, C. Lewandowski, R. Silbergleit   +7 more
semanticscholar   +1 more source

Midazolam microdose to determine systemic and pre-systemic metabolic CYP3A activity in humans.

British Journal of Clinical Pharmacology, 2015
AIM We aimed to establish a method to assess systemic and pre-systemic cytochrome P450 (CYP) 3A activity using ineffective microgram doses of midazolam. METHODS In an open, one sequence, crossover study, 16 healthy participants received intravenous and
N. Hohmann, F. Kocheise, A. Carls, J. Burhenne, W. Haefeli, G. Mikus   +5 more
semanticscholar   +1 more source

Effects of intravenous midazolam during spinal anaesthesia for caesarian section [PDF]

, 2016
Background: Spinal anaesthesia for caesarian section is associated with hypotension, bradycardia, and nausea and vomiting. The study was done to evaluate the safety and efficacy of sub hypnotic dose of midazolam in prevention of intraoperative ...
Borah, Susmita, Deka, Bipul, Laha, Amal Kumar, Talukdar, Bharat   +3 more
core   +2 more sources

Comparison of Oral Midazolam With Intravenous Midazolam for Sedation Children During Upper Gastrointestinal Endoscopy

Acta Medica Iranica, 2016
Upper endoscopy is a common procedure for the diagnosis and treatment of upper digestive tract diseases. The increasing number of pediatric gastrointestinal procedures has led to increasing attention on the safety and efficacy of medications used for ...
Ahmad Khodadad, Majid Aflatoonian, Rozita Jalilian, Nazanin Babaei, Farzaneh Motamed, Alireza Ebrahime Soltani, Behnaz Rasoolzadeh, Fatemeh Motavasselian, Nima Rezaei   +8 more
doaj  

Locomotor differences in Mongolian gerbils with the effects of midazolam administration in the form of eye drops [PDF]

, 2014
Background: Midazolam is a sedative-hypnotic agent with amnestic and anticonvulsant properties that can be administrated to mammals through various routes, such as intravenous, intramuscular, oral, intrathecal, rectal, and buccal.
Akkaya, Akcan, Apuhan, Tayfun, Ayaz, Erol, Bayir, Hakan, Demirhan, Abdullah, Erdurmus, Mesut, Kocoglu, Hasan, Tekelioglu, Umit Y   +7 more
core   +2 more sources

Propofol versus Midazolam for Upper Gastrointestinal Endoscopy in Cirrhotic Patients: A Meta-Analysis of Randomized Controlled Trials

PLoS ONE, 2015
Background Sedation during gastrointestinal endoscopy is often achieved using propofol or midazolam in general population. However, impaired protein synthesis, altered drug metabolism, and compromised hepatic blood flow in patients with liver cirrhosis ...
H. Tsai, Yu-Cih Lin, Ching-Lung Ko, Horng‐Yuan Lou, Ta-Liang Chen, K. Tam, Chien-Yu Chen   +6 more
semanticscholar   +1 more source

EVALUATION OF THE EFFECTS OF ADDING KETAMINE TO MORPHINE IN PCIA AFTER ORTHOPEDIC SURGERY [PDF]

Background: Midazolam is the only clinically available water – soluble benzodiazepine has been reported to have an antinoceptive effect through neuroaxial pathway .
اخوان اکبری, قدرت, ایمانی, فرناد, حیدریان, مجید, رحیم زاده, پوپک, شیرخانی, غلامرضا   +4 more
core  

Vocal learning promotes patterned inhibitory connectivity. [PDF]

, 2017
Skill learning is instantiated by changes to functional connectivity within premotor circuits, but whether the specificity of learning depends on structured changes to inhibitory circuitry remains unclear.
Brainard, Michael S, Cheung, Chung Yan J, Miller, Mark N   +2 more
core   +2 more sources

Effects of Morphine and Midazolam on Pharyngeal Function, Airway Protection, and Coordination of Breathing and Swallowing in Healthy Adults

Anesthesiology, 2015
Background:Drugs used for sedation in anesthesia and intensive care may cause pharyngeal dysfunction and increased risk for aspiration. In this study, the authors investigate the impact of sedative doses of morphine and midazolam on pharyngeal function ...
A. H. Hårdemark Cedborg, E. Sundman, K. Bodén, H. W. Hedström, R. Kuylenstierna, O. Ekberg, L. Eriksson   +6 more
semanticscholar   +1 more source

Preparation of Nanocrystals for Insoluble Drugs by Top-Down Nanotechnology with Improved Solubility and Bioavailability

Molecules, 2020
Midazolam is a rapidly effective benzodiazepine drug that is widely used as a sedative worldwide. Due to its poor solubility in a neutral aqueous solution, the clinical use of midazolam is significantly limited.
Xun Zhang, Zhiguo Li, Jing Gao, Zengming Wang, Xiang Gao, Nan Liu, Meng Li, Hui Zhang, Aiping Zheng   +8 more
doaj   +1 more source