Results 11 to 20 of about 115,017 (336)

The effects of Andrographis paniculata (Burm.f.) Nees on the pharmacokinetics and pharmacodynamics of midazolam in healthy volunteers [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2012
Andrographis paniculata (Burm.f.) Nees has been widely used for centuries in Asia for the treatment of common coldand diarrhea. Although it was previously reported to inhibit cytochrome P450 in vitro, the potential to cause herb-druginteraction has been ...
Malinee Wongnawa   +4 more
core   +2 more sources

Efficacy of remimazolam versus midazolam for procedural sedation: post hoc integrated analyses of three phase 3 clinical trials

open access: yesEndoscopy International Open, 2022
Background and study aims Remimazolam is an ultra-short acting, fast onset/fast offset benzodiazepine for intravenous use in procedural sedation, general anesthesia, and Intensive Care Unit sedation.
Van-Anh Dao   +2 more
doaj   +1 more source

Avoiding the incompatibility of peripheral parenteral nutrition solution and midazolam injection for intravenous sedation

open access: yesFujita Medical Journal, 2021
Objectives: We have observed white turbidity when a midazolam injection is administered from a lateral tube during the administration of a peripheral parenteral nutrition (PPN) solution. The aim of the current study was to determine how to avoid compound
Akihiko Futamura   +4 more
doaj   +1 more source

Perbedaan Waktu Pulih Sadar Anestesi Umum Sevofluran dengan Premedikasi Midazolam dan tanpa Premedikasi Midazolam

open access: yesJurnal Anestesi Perioperatif, 2022
Pemberian premedikasi midazolam memberikan efek sedasi yang panjang sehingga menimbulkan pulih sadar yang lebih lama. Tujuan penelitian ini adalah mengetahui perbedaan waktu pulih sadar anestesi umum sevofluran dengan dan tanpa premedikasi midazolam ...
Purwoko Purwoko   +2 more
doaj   +1 more source

Developing a Knowledge Graph Framework for Pharmacokinetic Natural Product-Drug Interactions [PDF]

open access: yesJournal of Biomedical Informatics 140 (2023) 104341, 2022
Pharmacokinetic natural product-drug interactions (NPDIs) occur when botanical natural products are co-consumed with pharmaceutical drugs. Understanding mechanisms of NPDIs is key to preventing adverse events. We constructed a knowledge graph framework, NP-KG, as a step toward computational discovery of pharmacokinetic NPDIs.
arxiv   +1 more source

Inflammation and cardiovascular status impact midazolam pharmacokinetics in critically ill children: An observational, prospective, controlled study

open access: yesPharmacology Research & Perspectives, 2022
Altered physiology caused by critical illness may change midazolam pharmacokinetics and thereby result in adverse reactions and outcomes in this vulnerable patient population.
Bikalpa Neupane   +6 more
doaj   +1 more source

The effect of midazolam dose and age on the paradoxical midazolam reaction in Korean pediatric patients [PDF]

open access: yesKorean Journal of Anesthesiology, 2013
BackgroundAlthough midazolam administration may occasionally induce a paradoxical episode, such as threatened crying and violent behavior in children, systematic studies on the causes of paradoxical reaction are limited.
Young Hee Shin   +8 more
doaj   +1 more source

Midazolam impacts acetyl-And butyrylcholinesterase genes: An epigenetic explanation for postoperative delirium?

open access: yesPLoS ONE, 2022
Midazolam is a widely used short-acting benzodiazepine. However, midazolam is also criticized for its deliriogenic potential. Since delirium is associated with a malfunction of the neurotransmitter acetylcholine, midazolam appears to interfere with its ...
Katharina Rump   +11 more
doaj   +1 more source

Midazolam impedes lung carcinoma cell proliferation and migration via EGFR/MEK/ERK signaling pathway

open access: yesOpen Medicine, 2023
Non-small-cell lung cancer (NSCLC) is a dominating type of lung cancer with high morbidity and mortality. Midazolam has been reported to promote cell apoptosis in NSCLC, but the molecular mechanism of midazolam remains to be further explored.
Zhang Xiangchao   +3 more
doaj   +1 more source

Prescription drug forms with midazolam [PDF]

open access: yesFarmacja Polska, 2021
Midazolam is a benzodiazepine derivative. It is characterized by a short half-life. It has a strong sedative, anxiolytic and hypnotic effect. It also acts as an anticonvulsant and relaxes skeletal muscles.
Anna Czech, Renata Jachowicz
doaj   +1 more source

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