Results 11 to 20 of about 115,017 (336)
The effects of Andrographis paniculata (Burm.f.) Nees on the pharmacokinetics and pharmacodynamics of midazolam in healthy volunteers [PDF]
Andrographis paniculata (Burm.f.) Nees has been widely used for centuries in Asia for the treatment of common coldand diarrhea. Although it was previously reported to inhibit cytochrome P450 in vitro, the potential to cause herb-druginteraction has been ...
Malinee Wongnawa+4 more
core +2 more sources
Background and study aims Remimazolam is an ultra-short acting, fast onset/fast offset benzodiazepine for intravenous use in procedural sedation, general anesthesia, and Intensive Care Unit sedation.
Van-Anh Dao+2 more
doaj +1 more source
Objectives: We have observed white turbidity when a midazolam injection is administered from a lateral tube during the administration of a peripheral parenteral nutrition (PPN) solution. The aim of the current study was to determine how to avoid compound
Akihiko Futamura+4 more
doaj +1 more source
Pemberian premedikasi midazolam memberikan efek sedasi yang panjang sehingga menimbulkan pulih sadar yang lebih lama. Tujuan penelitian ini adalah mengetahui perbedaan waktu pulih sadar anestesi umum sevofluran dengan dan tanpa premedikasi midazolam ...
Purwoko Purwoko+2 more
doaj +1 more source
Developing a Knowledge Graph Framework for Pharmacokinetic Natural Product-Drug Interactions [PDF]
Pharmacokinetic natural product-drug interactions (NPDIs) occur when botanical natural products are co-consumed with pharmaceutical drugs. Understanding mechanisms of NPDIs is key to preventing adverse events. We constructed a knowledge graph framework, NP-KG, as a step toward computational discovery of pharmacokinetic NPDIs.
arxiv +1 more source
Altered physiology caused by critical illness may change midazolam pharmacokinetics and thereby result in adverse reactions and outcomes in this vulnerable patient population.
Bikalpa Neupane+6 more
doaj +1 more source
The effect of midazolam dose and age on the paradoxical midazolam reaction in Korean pediatric patients [PDF]
BackgroundAlthough midazolam administration may occasionally induce a paradoxical episode, such as threatened crying and violent behavior in children, systematic studies on the causes of paradoxical reaction are limited.
Young Hee Shin+8 more
doaj +1 more source
Midazolam is a widely used short-acting benzodiazepine. However, midazolam is also criticized for its deliriogenic potential. Since delirium is associated with a malfunction of the neurotransmitter acetylcholine, midazolam appears to interfere with its ...
Katharina Rump+11 more
doaj +1 more source
Midazolam impedes lung carcinoma cell proliferation and migration via EGFR/MEK/ERK signaling pathway
Non-small-cell lung cancer (NSCLC) is a dominating type of lung cancer with high morbidity and mortality. Midazolam has been reported to promote cell apoptosis in NSCLC, but the molecular mechanism of midazolam remains to be further explored.
Zhang Xiangchao+3 more
doaj +1 more source
Prescription drug forms with midazolam [PDF]
Midazolam is a benzodiazepine derivative. It is characterized by a short half-life. It has a strong sedative, anxiolytic and hypnotic effect. It also acts as an anticonvulsant and relaxes skeletal muscles.
Anna Czech, Renata Jachowicz
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