Results 11 to 20 of about 136,839 (238)

Phenobarbital, Midazolam Pharmacokinetics, Effectiveness, and Drug-Drug Interaction in Asphyxiated Neonates Undergoing Therapeutic Hypothermia [PDF]

Neonatology, 2019
Background: Phenobarbital and midazolam are commonly used drugs in (near-)term neonates treated with therapeutic hypothermia for hypoxic-ischaemic encephalopathy, for sedation, and/or as anti-epileptic drug. Phenobarbital is an inducer of cytochrome P450
Laurent M A Favié, F. Groenendaal, M. V. D. van den Broek, C. Rademaker, T. D. de Haan, Henrica L. M. van Straaten, P. Dijk, A. V. van Heijst, S. Simons, K. Dijkman, M. Rijken, I. Zonnenberg, F. Cools, A. Zecic, J. H. van der Lee, D. Nuytemans, F. van Bel, T. Egberts, A. Huitema   +18 more
semanticscholar   +3 more sources

Anti-cancer effect of midazolam via downregulating YWHAH in papillary thyroid cancer cells. [PDF]

Discov Oncol
The work is aimed to investigate whether midazolam functions in thyroid cancer and reveal the potential mechanism of action. Cell viability was detected by CCK-8 method when treated by varying doses of midazolam to detect the cytotoxicity of midazolam on
Li Y, Tan AP, Zhong YS.
europepmc   +2 more sources

Investigating the Relationship Between Midazolam Serum Concentrations and Paediatric Delirium in Critically Ill Children. [PDF]

Pediatr Rep
Objectives: Intravenous midazolam is widely used for sedation in critically ill children. Sometimes, these children develop a paediatric delirium (PD). Our aim was to determine the relationship between midazolam serum concentration and the development of
Marongiu S, Bolhuis MS, Touw DJ, Kneyber MCJ.   +3 more
europepmc   +2 more sources

Comparison of Oral Midazolam and Promethazine with Oral Midazolam alone for Sedating Children during Computed Tomography [PDF]

Emergency, 2015
Introduction: Both midazolam and promethazine are recommended to be used as sedatives in many studies but each have some side effects that limits their use. Combination therapy as an alternative method, may decreases these limitations.
Hassan Barzegari, Behzad Zohrevandi, Kambiz Masoumi, Arash Forouzan, Ali Asgari Darian, Shaqayeq Khosravi   +5 more
doaj   +4 more sources

The effects of Andrographis paniculata (Burm.f.) Nees on the pharmacokinetics and pharmacodynamics of midazolam in healthy volunteers [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2012
Andrographis paniculata (Burm.f.) Nees has been widely used for centuries in Asia for the treatment of common coldand diarrhea. Although it was previously reported to inhibit cytochrome P450 in vitro, the potential to cause herb-druginteraction has been ...
Malinee Wongnawa, Potjanee Soontaro, Wibool Riditid, Payom Wongpoowarak, Suwit Ruengkittisakul   +4 more
doaj   +2 more sources

The Clearance of Midazolam and Metabolites during Continuous Renal Replacement Therapy in Critically Ill Patients with COVID-19 [PDF]

, 2023
Introduction: Midazolam-based continuous intravenous sedation in patients admitted to the intensive care unit (ICU) was a necessity during the COVID-19 pandemic. However, benzodiazepine-based sedation is associated with a high incidence of benzodiazepine-
Baidjoe, Lauren, De Geus, Hilde R.H., Endeman, Henrik, Gommers, Diederik A.M.P.J., Hunfeld, Nicole G.M., Koch, Birgit C.P., Smeets, Tim J.L., Valkenburg, Abraham J.   +7 more
core   +3 more sources

Effect of Intranasal Dexmedetomidine or Midazolam for Premedication on the Occurrence of Respiratory Adverse Events in Children Undergoing Tonsillectomy and Adenoidectomy

JAMA Network Open, 2022
Key Points Question Do preoperative sedatives such as midazolam and dexmedetomidine have a protective effect against perioperative respiratory adverse events (PRAEs) while achieving adequate sedative effect?
Fangming Shen, Qin Zhang, Yahui Xu, Xing-he Wang, Jiayi Xia, Chao Chen, He Liu, Yueying Zhang   +7 more
semanticscholar   +1 more source

Efficacy of remimazolam versus midazolam for procedural sedation: post hoc integrated analyses of three phase 3 clinical trials

Endoscopy International Open, 2022
Background and study aims Remimazolam is an ultra-short acting, fast onset/fast offset benzodiazepine for intravenous use in procedural sedation, general anesthesia, and Intensive Care Unit sedation.
Van-Anh Dao, Frank Schippers, Thomas Stöhr   +2 more
doaj   +1 more source

Midazolam Premedication Immediately Before Surgery Is Not Associated With Early Postoperative Delirium

Anesthesia and Analgesia, 2021
BACKGROUND: Postoperative delirium is common among older surgical patients and may be associated with anesthetic management during the perioperative period.
Man-Ling Wang, Jie Min, L. Sands, J. Leung   +3 more
semanticscholar   +1 more source

Avoiding the incompatibility of peripheral parenteral nutrition solution and midazolam injection for intravenous sedation

Fujita Medical Journal, 2021
Objectives: We have observed white turbidity when a midazolam injection is administered from a lateral tube during the administration of a peripheral parenteral nutrition (PPN) solution. The aim of the current study was to determine how to avoid compound
Akihiko Futamura, Takashi Higashiguchi, Takeshi Chihara, Yuka Yokota, Yoshinori Itani   +4 more
doaj   +1 more source