Results 11 to 20 of about 152,722 (386)

Midazolam for sedation before procedures in adults and children: a systematic review update

Systematic Reviews, 2021
Background Midazolam is used for sedation before diagnostic and therapeutic medical procedures by several routes including oral, intravenous, intranasal and intramuscular. This is an update of a Cochrane review published in 2016, which aimed to determine
Aaron Conway, Kristina Chang, Sebastian Mafeld, Joanna Sutherland   +3 more
doaj   +2 more sources

Effect of Intranasal Dexmedetomidine or Midazolam for Premedication on the Occurrence of Respiratory Adverse Events in Children Undergoing Tonsillectomy and Adenoidectomy

JAMA Network Open, 2022
Key Points Question Do preoperative sedatives such as midazolam and dexmedetomidine have a protective effect against perioperative respiratory adverse events (PRAEs) while achieving adequate sedative effect?
Fangming Shen, Qin Zhang, Yahui Xu, Xing-he Wang, Jiayi Xia, Chao Chen, He Liu, Yueying Zhang   +7 more
semanticscholar   +1 more source

Midazolam Premedication Immediately Before Surgery Is Not Associated With Early Postoperative Delirium

Anesthesia and Analgesia, 2021
BACKGROUND: Postoperative delirium is common among older surgical patients and may be associated with anesthetic management during the perioperative period.
Man-Ling Wang, Jie Min, L. Sands, J. Leung   +3 more
semanticscholar   +1 more source

Midazolam: an essential palliative care drug

Palliative Care and Social Practice, 2020
Midazolam is a commonly used benzodiazepine in palliative care and is considered one of the four essential drugs needed for the promotion of quality care in dying patients.
E. Prommer
semanticscholar   +1 more source

Prehospital midazolam use and outcomes among patients with out-of-hospital status epilepticus

Neurology, 2020
Objective To examine the use of benzodiazepines and the association between low benzodiazepine dose, breakthrough seizures, and respiratory support in patients with status epilepticus.
E. Guterman, Joseph K Sanford, John P. Betjemann, Li Zhang, J. Burke, D. Lowenstein, S. Josephson, K. Sporer   +7 more
semanticscholar   +1 more source

Midazolam impacts acetyl-And butyrylcholinesterase genes: An epigenetic explanation for postoperative delirium?

PLoS ONE, 2022
Midazolam is a widely used short-acting benzodiazepine. However, midazolam is also criticized for its deliriogenic potential. Since delirium is associated with a malfunction of the neurotransmitter acetylcholine, midazolam appears to interfere with its ...
Katharina Rump, Caroline Holtkamp, Lars Bergmann, Hartmuth Nowak, Matthias Unterberg, Jennifer Orlowski, Patrick Thon, Zainab Bazzi, Maha Bazzi, Michael Adamzik, Björn Koos, Tim Rahmel   +11 more
doaj   +1 more source

Midazolam alleviates cellular senescence in SH‐SY5Y neuronal cells in Alzheimer's disease

Brain and Behavior, 2023
Background Alzheimer's disease (AD) impacts the daily life of aging people. Oligomerized amyloid β (Aβ)‐associated neuronal senescence is involved in the pathological mechanism of AD.
Ping Wang, Peipei Wang, Hengfei Luan, Yong Wu, Ying Chen   +4 more
doaj   +1 more source

Individual differences in the effects of midazolam on anxiety-like behavior, learning, reward, and choice behavior in male mice

Frontiers in Psychiatry, 2023
IntroductionThe aim of the present study was to investigate the behavioral effects of the benzodiazepine midazolam in male mice, in models of anxiolysis, learning, and abuse-related effects.MethodsIn a first set of experiments, male Swiss mice were ...
Caio Jovita-Farias, Meagan E. Follett, Behaim C. Dias-Junior, Yasmim A. Serra, Natali D. Kisaki, Thaísa Barros-Santos, Nailton M. S. de Jesus, Isa R. S. Rodrigues, Larissa E. L. Macedo, Elena L. A. Malpezzi-Marinho, Alexandre J. Oliveira-Lima, Eduardo Ary Villela Marinho, James K. Rowlett, Lais F. Berro, Lais F. Berro   +14 more
doaj   +1 more source

Effect of sedative premedication with oral midazolam on postanesthesia care unit delirium in older adults: a secondary analysis following an uncontrolled before-after design

Perioperative Medicine, 2022
Background Sedative premedication with benzodiazepines has been linked with prolonged recovery and inadequate emergence during the immediate postoperative period.
Karin Stuff, Elena Kainz, Ursula Kahl, Hans Pinnschmidt, Stefanie Beck, Franziska von Breunig, Rainer Nitzschke, Sandra Funcke, Christian Zöllner, Marlene Fischer   +9 more
doaj   +1 more source

Prescription drug forms with midazolam [PDF]

Farmacja Polska, 2021
Midazolam is a benzodiazepine derivative. It is characterized by a short half-life. It has a strong sedative, anxiolytic and hypnotic effect. It also acts as an anticonvulsant and relaxes skeletal muscles.
Anna Czech, Renata Jachowicz
doaj   +1 more source