Results 11 to 20 of about 147,753 (385)

Effect of Intranasal Dexmedetomidine or Midazolam for Premedication on the Occurrence of Respiratory Adverse Events in Children Undergoing Tonsillectomy and Adenoidectomy

JAMA Network Open, 2022
Key Points Question Do preoperative sedatives such as midazolam and dexmedetomidine have a protective effect against perioperative respiratory adverse events (PRAEs) while achieving adequate sedative effect?
Fangming Shen, Qin Zhang, Yahui Xu, Xing-he Wang, Jiayi Xia, Chao Chen, He Liu, Yueying Zhang   +7 more
semanticscholar   +1 more source

Midazolam Premedication Immediately Before Surgery Is Not Associated With Early Postoperative Delirium

Anesthesia and Analgesia, 2021
BACKGROUND: Postoperative delirium is common among older surgical patients and may be associated with anesthetic management during the perioperative period.
Man-Ling Wang, Jie Min, L. Sands, J. Leung   +3 more
semanticscholar   +1 more source

Midazolam: an essential palliative care drug

Palliative Care and Social Practice, 2020
Midazolam is a commonly used benzodiazepine in palliative care and is considered one of the four essential drugs needed for the promotion of quality care in dying patients.
E. Prommer
semanticscholar   +1 more source

Prehospital midazolam use and outcomes among patients with out-of-hospital status epilepticus

Neurology, 2020
Objective To examine the use of benzodiazepines and the association between low benzodiazepine dose, breakthrough seizures, and respiratory support in patients with status epilepticus.
E. Guterman, Joseph K Sanford, John P. Betjemann, Li Zhang, J. Burke, D. Lowenstein, S. Josephson, K. Sporer   +7 more
semanticscholar   +1 more source

Midazolam impedes lung carcinoma cell proliferation and migration via EGFR/MEK/ERK signaling pathway

Open Medicine, 2023
Non-small-cell lung cancer (NSCLC) is a dominating type of lung cancer with high morbidity and mortality. Midazolam has been reported to promote cell apoptosis in NSCLC, but the molecular mechanism of midazolam remains to be further explored.
Zhang Xiangchao, Han Zhe, Li Zhengjun, Wang Tao   +3 more
doaj   +1 more source

Individual differences in the effects of midazolam on anxiety-like behavior, learning, reward, and choice behavior in male mice

Frontiers in Psychiatry, 2023
IntroductionThe aim of the present study was to investigate the behavioral effects of the benzodiazepine midazolam in male mice, in models of anxiolysis, learning, and abuse-related effects.MethodsIn a first set of experiments, male Swiss mice were ...
Caio Jovita-Farias, Meagan E. Follett, Behaim C. Dias-Junior, Yasmim A. Serra, Natali D. Kisaki, Thaísa Barros-Santos, Nailton M. S. de Jesus, Isa R. S. Rodrigues, Larissa E. L. Macedo, Elena L. A. Malpezzi-Marinho, Alexandre J. Oliveira-Lima, Eduardo Ary Villela Marinho, James K. Rowlett, Lais F. Berro, Lais F. Berro   +14 more
doaj   +1 more source

Midazolam inhibits hippocampal long-term potentiation and learning through dual central and peripheral benzodiazepine receptor activation and neurosteroidogenesis [PDF]

, 2010
Benzodiazepines (BDZs) enhance GABA(A) receptor inhibition by direct actions on central BDZ receptors (CBRs). Although some BDZs also bind mitochondrial receptors [translocator protein (18 kDa) (TSPO)] and promote the synthesis of GABA-enhancing ...
Izumi, Yukitoshi, O\u27Dell, Kazuko A, Tokuda, Kazuhiro, Zorumski, Charles F   +3 more
core   +2 more sources

Opisthotonos and midazolam [PDF]

Journal of Pediatric Neurology, 2015
A 3-year-child, weighing 11.4 kgs, was admitted in the accident and emergency ward in status epilepticus of more than one hour duration. He was administered diazepam suppository followed by 3 doses of intravenous diazepam. When diazepam failed to control the status epilepticus a loading dose of phenytoin sodium 200 mg (18 mg per kg) was given. This too
Roshan Koul, Javed Hashim, Masod Ahmed
openaire   +2 more sources

Ketamine for Rapid Reduction of Suicidal Thoughts in Major Depression: A Midazolam-Controlled Randomized Clinical Trial.

American Journal of Psychiatry, 2017
OBJECTIVE Pharmacotherapy to rapidly relieve suicidal ideation in depression may reduce suicide risk. Rapid reduction in suicidal thoughts after ketamine treatment has mostly been studied in patients with low levels of suicidal ideation.
M. Grunebaum, H. Galfalvy, Tse-Hwei Choo, J. Keilp, V. Moitra, Michelle S Parris, Julia E. Marver, A. Burke, M. Milak, M. Sublette, M. Oquendo, J. Mann   +11 more
semanticscholar   +1 more source

Midazolam alleviates cellular senescence in SH‐SY5Y neuronal cells in Alzheimer's disease

Brain and Behavior, 2023
Background Alzheimer's disease (AD) impacts the daily life of aging people. Oligomerized amyloid β (Aβ)‐associated neuronal senescence is involved in the pathological mechanism of AD.
Ping Wang, Peipei Wang, Hengfei Luan, Yong Wu, Ying Chen   +4 more
doaj   +1 more source