Results 21 to 30 of about 136,839 (238)
Jurnal Anestesi Perioperatif, 2022 Pemberian premedikasi midazolam memberikan efek sedasi yang panjang sehingga menimbulkan pulih sadar yang lebih lama. Tujuan penelitian ini adalah mengetahui perbedaan waktu pulih sadar anestesi umum sevofluran dengan dan tanpa premedikasi midazolam ...
Purwoko Purwoko +2 more
doaj +1 more source
Developing a Knowledge Graph Framework for Pharmacokinetic Natural Product-Drug Interactions [PDF]
Journal of Biomedical Informatics 140 (2023) 104341, 2022 Pharmacokinetic natural product-drug interactions (NPDIs) occur when botanical natural products are co-consumed with pharmaceutical drugs. Understanding mechanisms of NPDIs is key to preventing adverse events. We constructed a knowledge graph framework, NP-KG, as a step toward computational discovery of pharmacokinetic NPDIs.
arxiv +1 more source
Pharmacology Research & Perspectives, 2022 Altered physiology caused by critical illness may change midazolam pharmacokinetics and thereby result in adverse reactions and outcomes in this vulnerable patient population.
Bikalpa Neupane +6 more
doaj +1 more source
The effect of midazolam dose and age on the paradoxical midazolam reaction in Korean pediatric patients [PDF]
Korean Journal of Anesthesiology, 2013 BackgroundAlthough midazolam administration may occasionally induce a paradoxical episode, such as threatened crying and violent behavior in children, systematic studies on the causes of paradoxical reaction are limited.
Young Hee Shin +8 more
doaj +1 more source
Midazolam: an essential palliative care drug
Palliative Care and Social Practice, 2020 Midazolam is a commonly used benzodiazepine in palliative care and is considered one of the four essential drugs needed for the promotion of quality care in dying patients.
E. Prommer
semanticscholar +1 more source
PLoS ONE, 2022 Midazolam is a widely used short-acting benzodiazepine. However, midazolam is also criticized for its deliriogenic potential. Since delirium is associated with a malfunction of the neurotransmitter acetylcholine, midazolam appears to interfere with its ...
Katharina Rump +11 more
doaj +1 more source
Prehospital midazolam use and outcomes among patients with out-of-hospital status epilepticus
Neurology, 2020 Objective To examine the use of benzodiazepines and the association between low benzodiazepine dose, breakthrough seizures, and respiratory support in patients with status epilepticus.
E. Guterman +7 more
semanticscholar +1 more source
American Journal of Psychiatry, 2017 OBJECTIVE Pharmacotherapy to rapidly relieve suicidal ideation in depression may reduce suicide risk. Rapid reduction in suicidal thoughts after ketamine treatment has mostly been studied in patients with low levels of suicidal ideation.
M. Grunebaum +11 more
semanticscholar +1 more source
Midazolam impedes lung carcinoma cell proliferation and migration via EGFR/MEK/ERK signaling pathway
Open Medicine, 2023 Non-small-cell lung cancer (NSCLC) is a dominating type of lung cancer with high morbidity and mortality. Midazolam has been reported to promote cell apoptosis in NSCLC, but the molecular mechanism of midazolam remains to be further explored.
Zhang Xiangchao +3 more
doaj +1 more source
Midazolam inhibits hippocampal long-term potentiation and learning through dual central and peripheral benzodiazepine receptor activation and neurosteroidogenesis [PDF]
, 2010 Benzodiazepines (BDZs) enhance GABA(A) receptor inhibition by direct actions on central BDZ receptors (CBRs). Although some BDZs also bind mitochondrial receptors [translocator protein (18 kDa) (TSPO)] and promote the synthesis of GABA-enhancing ...
Izumi, Yukitoshi +3 more
core +2 more sources