Results 21 to 30 of about 58,995 (146)

Midazolam for sedation before procedures in adults and children: a systematic review update

open access: yesSystematic Reviews, 2021
Background Midazolam is used for sedation before diagnostic and therapeutic medical procedures by several routes including oral, intravenous, intranasal and intramuscular. This is an update of a Cochrane review published in 2016, which aimed to determine
Aaron Conway   +3 more
doaj   +1 more source

The influence of DNA polymorphism of multidrug resistant 1 (MDR1) on the effect of midazolam pretreatment in children [PDF]

open access: yesKorean Journal of Anesthesiology, 2012
BackgroundPatients showed a different response following intravenous midazolam injection. Some children showed irritability or were not sedated by midazolam.
Hyo-Jin Byon   +5 more
doaj   +1 more source

Posttraumatic midazolam administration does not influence brain damage after experimental traumatic brain injury

open access: yesBMC Anesthesiology, 2022
Background The benzodiazepine midazolam is a γ-aminobutyric acid (GABA)-A receptor agonist frequently used for sedation or stress control in patients suffering from traumatic brain injury (TBI).
Anne Sebastiani   +3 more
doaj   +1 more source

A method for measuring the molecular ratio of inhalation to exhalation and effect of inspired oxygen levels on oxygen consumption

open access: yesScientific Reports, 2021
Using a new method for measuring the molecular ratio (R) of inhalation to exhalation, we investigated the effect of high fraction of inspired oxygen (FIO2) on oxygen consumption (VO2), carbon dioxide generation (VCO2), and respiratory quotient (RQ) in ...
Koichiro Shinozaki   +9 more
doaj   +1 more source

The Antinociceptive Effects of Midazolam on Three Different Types of Nociception in Mice

open access: yesJournal of Pharmacological Sciences, 2009
Antinociceptive effects of systemically administered midazolam remain controversial. The present study was performed to investigate its antinociceptive effects on different types of nociception in mice. Four different doses of midazolam (1, 3, 10, and 30
Shunsuke Chiba   +3 more
doaj   +1 more source

Postoperative expressive aphasia associated with intravenous midazolam administration: a 5-year retrospective case-control study

open access: yesJournal of International Medical Research, 2020
Objectives This study aimed to investigate the epidemiology of intravenous midazolam-induced postoperative expressive aphasia (EA). Methods The incidence rate, risk ratio, and contributing factors to intravenous midazolam-induced postoperative EA were ...
Saecheol Oh   +3 more
doaj   +1 more source

Comparison of the effects of midazolam, dexamethasone, ondansetron and propofol on the prevention and control of opioid-induced pruritus after spinal anaesthesia with bupivacaine combined with fentanyl in femoral fracture surgery

open access: yesAdvances in Human Biology, 2023
Introduction: The present study set out to compare the effects of midazolam, dexamethasone, ondansetron and propofol on the prevention and control of opioid-induced pruritus after spinal anaesthesia with bupivacaine and fentanyl as adjuvants in femoral ...
Hesameddin Modir   +3 more
doaj   +1 more source

NE contribution to rebooting unconsciousness caused by midazolam

open access: yeseLife
The advent of midazolam holds profound implications for modern clinical practice. The hypnotic and sedative effects of midazolam afford it broad clinical applicability.
LeYuan Gu   +14 more
doaj   +1 more source

Anti-cancer effect of midazolam via downregulating YWHAH in papillary thyroid cancer cells

open access: yesDiscover Oncology
The work is aimed to investigate whether midazolam functions in thyroid cancer and reveal the potential mechanism of action. Cell viability was detected by CCK-8 method when treated by varying doses of midazolam to detect the cytotoxicity of midazolam on
Yang Li, Ai-Ping Tan, Yu-Shan Zhong
doaj   +1 more source

Inherited and Acquired Determinants of Hepatic CYP3A Activity in Humans

open access: yesFrontiers in Genetics, 2020
Human CYP3A enzymes (including CYP3A4 and CYP4A5) metabolize about 40% of all drugs and numerous other environmental and endogenous substances. CYP3A activity is highly variable within and between humans.
Johannes Matthaei   +13 more
doaj   +1 more source

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