Results 61 to 70 of about 151,098 (403)
Alcohol Withdrawal – Therapeutical Management in Surgical Patients with Upper Intestinal Bleeding [PDF]
Psychological dependence involves a desire to use a drug to avoid the unpleasant withdrawal syndrome that results from cessation of exposure to it. Alcohol withdrawal syndrome is one of the most feared complications of alcohol addiction and sometimes can
Bogdan, Popescu +5 more
core +4 more sources
A 3D bone scaffold with osteogenic properties and capable of hardening in vivo is developed. The scaffold is implanted in a ductile state, and a phase transformation of the ceramic induces the stiffening and strengthening of the scaffold in vivo. Abstract Calcium phosphate 3D printing has revolutionized customized bone grafting.
Miguel Mateu‐Sanz +7 more
wiley +1 more source
The role of biotransformation processes in mediating interactions between psychotropic drugs and natural products [PDF]
Many patients are not aware that natural products such as fruit juices or plant infusions can cause significant interactions with several drugs, some of which can be dangerous, especially when the medical treatment is for neurological or psychiatric ...
Bacinschi, Nicolae +6 more
core +2 more sources
A liposomal formulation for methotrexate enables minimally invasive, sustained intraocular drug delivery for over six weeks with a single injection. Developed for treating intraocular diseases like lymphoma and PVR, it offers excellent biocompatibility in vivo in a porcine model.
Maximilian Hammer +17 more
wiley +1 more source
Oral administration of a low dose of midazolam (75μg) as an in vivo probe for CYP3A activity [PDF]
Objective: We investigated whether the oral administration of a low dose (75µg) of midazolam, a CYP3A probe, can be used to measure the in vivo CYP3A activity.
Aubert, Anne-Catherine +10 more
core
A bone substitute with gentamicin physically precipitated onto the surface of carbonate apatite exhibits prompt drug release, high bactericidal activity, and osteogenic capacity. Efficient antibacterial activity mitigates early postoperative neutrophil accumulation, the status of which may serve as a potential parameter for evaluating the antibacterial
Linghao Xiao +6 more
wiley +1 more source
A Comparison of Moderate Oral Sedation Drug Regimens for Pediatric Dental Treatment: A Pilot Study [PDF]
Purpose: Compare moderate oral sedation of pediatric patients using Hydroxyzine and Meperidine with either Diazepam or Midazolam in management of pediatric dental patients. Methods: Randomized, double-blind, crossover pilot study of patients 3 to 7 years
Parikh, Ojas A
core +1 more source
Lipopolysaccharide (LPS) stimulates the production of succinic acid in lung tissue, which promotes macrophages endocytosis and the formation of multivesicular bodies (MVBs). These MVBs release profibrotic extracellular vesicles (EVs), facilitating the transfer of integrin beta1 (ITGβ1) transfer and subsequently activating fibroblasts, thereby ...
Wenyu Yang +10 more
wiley +1 more source
The effect of Midazolam and Propranolol on fear memory reconsolidation in ethanol-withdrawn rats: Influence of D-cycloserine [PDF]
Background: Withdrawal from chronic ethanol facilitates the formation of contextual fear memory and delays the onset to extinction, with its retrieval promoting an increase in ethanol consumption.
Espejo, Pablo Javier +4 more
core +1 more source
A novel bimetallic nanozyme (Fe2–NCs) with well‐defined Fe–Fe active sites is synthesized through a host–guest coordination strategy, which exhibits an exceptional therapeutic efficacy in osteoarthritis therapy. Experimental and theoretical analyses uncover the intrinsic catalytic mechanism at the atomic level, offering fundamental insights and design ...
Ting Ying +6 more
wiley +1 more source

