Results 71 to 80 of about 76,936 (284)

Inherited and Acquired Determinants of Hepatic CYP3A Activity in Humans

Frontiers in Genetics, 2020
Human CYP3A enzymes (including CYP3A4 and CYP4A5) metabolize about 40% of all drugs and numerous other environmental and endogenous substances. CYP3A activity is highly variable within and between humans.
Johannes Matthaei, Wagner Hugo Bonat, Reinhold Kerb, Mladen Vassilev Tzvetkov, Jakob Strube, Stefanie Brunke, Cordula Sachse-Seeboth, Daniel Sehrt, Ute Hofmann, Jacob von Bornemann Hjelmborg, Matthias Schwab, Matthias Schwab, Matthias Schwab, Jürgen Brockmöller   +13 more
doaj   +1 more source

Midazolam hypersensitivity during the transportation to theater -A case report- [PDF]

Korean Journal of Anesthesiology, 2010
This report describes a rare case of perioperative midazolam hypersensitivity in a patient without any history of allergy. A 39-year-old man was admitted for endoscopic pansinus surgery.
Jin-Young Hwang, Young-Tae Jeon, Hyo-Seok Na, Ji-Hyun Lee, Seong-Ju Choi, Seung Hye Jung   +5 more
doaj   +1 more source

Effects of oropharyngeal neuromuscular stimulation on the volumetric enlarged and reduced tongue base in minipigs

The Anatomical Record, EarlyView.
Abstract Hypoglossal nerve or tongue protruding muscle stimulation is a current treatment option for obstructive sleep apnea. Thus, the present study analyzed 3D deformations of the volumetric enlarged and reduced tongue base upon oropharyngeal neuromuscular stimulation.
Sydney Chen, Doris Haydee Rosero Salazar, Zi‐Jun Liu   +2 more
wiley   +1 more source

Prophylactic Antiemetic Effects of Midazolam, Ondansetron and their Combination after Middle Ear Surgery

مجله دانشکده پزشکی اصفهان, 2016
Background: The purpose of the present study was to evaluate the efficacy of midazolam-ondansetron combination in prevention of postoperative nausea and vomiting (PONV) after middle ear surgery and its comparison with using midazolam or ondansetron alone.
Azim Honarmand, Seyed Mohammad Reza Safavi, Mansoureh Chegeni   +2 more
doaj  

Drug Monitoring of Therapy with Midazolam in Patients with ARDS: A Single-Center Prospective Study

Medicina
Background and Objectives: One of the two primary classes of drugs administered in ICUs for pharmacological sedation is benzodiazepines. Among these, anesthesiologists consider midazolam the most commonly used and clinically significant agent.
Marek Grochla, Marcin Basiak, Bogusław Okopień, Piotr Knapik   +3 more
doaj   +1 more source

Comparison of Hemodynamic and Sedation Effects of Midazolam and Propofol

, 2015
Aim: In this study, we compared the sedation quality and cardiovascular and respiratory system effects of midazolam versus propofol in patients undergoing spinal anesthesia. Methods: 40 ASA I-III patients aged 20-70 years were enrolled.
Şermin Eminoğlu, Emel Koçergür, Nedret Ergüven   +2 more
core   +1 more source

Non‐Weightbearing in Hinged‐Knee Braces Locked in High Degrees of Flexion Shows High Hamstring Muscle Activation in Healthy Volunteers

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To determine the effect of various postoperative ambulation and bracing protocols on hamstring muscle group activation in healthy volunteers. Methods Hamstring muscle group activation was assessed via Myontec Mbody 3 Shorts. Volunteers ambulated 10 yards in conditions including walking unassisted, flat‐foot weightbearing (FFWB), FFWB with a ...
Christian E. Athanasian, Brendan Schwartz, Natalia Czerwonka, David P. Trofa, Richard C. Mather, Robert A. Christian   +5 more
wiley   +1 more source

A comparison of propofol and midazolam/meperidine sedation in upper gastrointestinal endoscopy

, 2016
Introduction : There is increasing interest in sedation for upper gastrointestinal endoscopy (UGE). Prospective randomized studies comparing sedation properties and complications of propofol and midazolam/meperidine in upper gastrointestinal endoscopy ...
Dogan Yildirim, Sinan Uzman, Bunyamin Gurbulak, Esin Kabul Gurbulak, Turgut Donmez, Adnan Hut   +5 more
core   +1 more source

Immune Complexes Shape the Pathogenicity of Autoantibodies in Systemic Autoimmune Diseases: Insights From an FcγRIIIA‐Reporter Assay

Arthritis &Rheumatology, EarlyView.
Objective Immune complexes (ICs), formed by autoantigen and autoantibody, play a pathogenic role in systemic autoimmune diseases through stimulation of Fcγ receptors (FcγR). However, studies investigating bioactivity of circulating ICs across various diseases remain limited.
Koji Suzuki, Masaru Takeshita, Yuki Imai, Hiroyuki Fukui, Kazunori Furuhashi, Kotaro Matsumoto, Jun Kikuchi, Keiko Yoshimoto, Yuko Kaneko   +8 more
wiley   +1 more source

Midazolam for sedation before procedures [PDF]

, 2016
Midazolam is used for sedation before diagnostic and therapeutic medical procedures. It is an imidazole benzodiazepine that has depressant effects on the central nervous system (CNS) with rapid onset of action and few adverse effects.
Conway, Aaron, ROLLEY, John; id_orcid, Sutherland, Joanna R., Rolley, John   +3 more
core   +1 more source