Results 71 to 80 of about 145,146 (385)

Advances in Microfluidic Cochlea‐On‐A‐Chip

open access: yesAdvanced Science, EarlyView.
This review systematically examines diverse cell sources for inner ear organoids and outlines stepwise induction protocols. Furthermore, it discusses current applications and prospective developments of cochlea‐on‐a‐chip technologies in areas such as deafness modeling, mechanistic studies, and drug evaluation, with particular focus on gene‐therapy drug
Tian Shen   +10 more
wiley   +1 more source

Chemical Bond Covalency in Superionic Halide Solid‐State Electrolytes

open access: yesAngewandte Chemie, EarlyView.
Achieving high conductivity in halide solid‐state electrolytes requires understanding key factors for ionic diffusion. This study provides direct evidence that metal‐halide covalent bonding controls superionic transitions and enhances Li+ mobility. Tailoring covalency through composition, demonstrated via in situ studies and simulations on bromide ...
Jiamin Fu   +17 more
wiley   +2 more sources

Sedation for Gastrointestinal Endoscopic Procedures in the Elderly: Getting Safer but Still Not Nearly Safe Enough [PDF]

open access: yes, 2006
Previously published UK reports showed that excessively large doses of benzodiazepines and opiates were being commonly used to sedate elderly patients for gastrointestinal (GI) endoscopy. This unsafe practice has lead to avoidable morbidity and mortality.
Bell, G. D.   +8 more
core  

Characterization of porcine hepatic and intestinal drug metabolizing CYP450 : comparison with human orthologues from a quantitative, activity and selectivity perspective [PDF]

open access: yes, 2019
Over the past two decades, the pig has gained attention as a potential model for human drug metabolism. Cytochrome P450 enzymes (CYP450), a superfamily of biotransformation enzymes, are pivotal in drug metabolism.
Croubels, Siska   +7 more
core   +1 more source

Effects of passiflora incarnata and midazolam for control of anxiety in patients undergoing dental extraction

open access: yesMedicina Oral, 2016
Background Anxiety symptoms are frequently observed in dental patients, whether they are undergoing simple or more invasive procedures such as surgery.
Liliane-Poconé Dantas   +3 more
semanticscholar   +1 more source

In Vivo Cytosolic Delivery of Biomolecules into Neurons for Super‐Resolution Imaging and Genome Modification

open access: yesAdvanced Science, EarlyView.
The N1 peptide specifically targets neurons, enabling cytosolic delivery of fluorescent dyes and proteins for super‐resolution imaging and functional genetic modification. Abstract Efficient delivery of biomolecules into neurons has significant impacts on therapeutic applications in the central nervous system (CNS) and fundamental neuroscience research.
Xiaoqian Ge   +16 more
wiley   +1 more source

NE contribution to rebooting unconsciousness caused by midazolam

open access: yeseLife
The advent of midazolam holds profound implications for modern clinical practice. The hypnotic and sedative effects of midazolam afford it broad clinical applicability.
LeYuan Gu   +14 more
doaj   +1 more source

Resonant Spin Amplification and Accumulation in MAPbI3 Single Crystals

open access: yesAdvanced Science, EarlyView.
Carrier spin dynamics are studied in a 20 µm thin MAPbI3 perovskite single crystal using time‐resolved Kerr ellipticity at cryogenic temperatures. Long spin relaxation (30 ns) and dephasing (21 ns) enable spin accumulation. Spin accumulation effects are discussed in detail along with carrier‐nuclear spin interactions.
Erik Kirstein   +6 more
wiley   +1 more source

Midazolam hypersensitivity during the transportation to theater -A case report- [PDF]

open access: yesKorean Journal of Anesthesiology, 2010
This report describes a rare case of perioperative midazolam hypersensitivity in a patient without any history of allergy. A 39-year-old man was admitted for endoscopic pansinus surgery.
Jin-Young Hwang   +5 more
doaj   +1 more source

Premedication With Midazolam Nasal Spray: An Alternative to Oral Midazolam in Children [PDF]

open access: yesAnesthesiology and Pain Medicine, 2011
Midazolam is a water soluble benzodiazepine which is frequently administered by intravenous and oral routes in our institution. Its nasal spray has become recently available.To compare the efficacy of midazolam administered orally and by intranasal spray, with the specific objective of assessing their efficacy in terms of acceptability to the patients,
Ravi K Verma   +3 more
openaire   +4 more sources

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