Results 71 to 80 of about 467,597 (305)
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
, 1999 Copyright 1999, Francisco Gomez. See also: http://atlas.geo.cornell.edu/dissertations/Gomez_1999.htmThe Atlas Mountains of North Africa, located in the African foreland of the Alpine mountain belts, comprise a 2,000 km long Cenozoic mountain chain ...
Gomez, Francisco
core
Floristic analysis of Marmoucha’s plant diversity (Middle Atlas, Morocco)
LAZAROA, 2013 Abstract As part of an ethnobotanical exploration among the Berbers of Marmoucha in the Middle Atlas in Morocco, a floristic analysis is conducted to inventory the existing plants and assess the extent of plant diversity in this area. Located in the eastern part of the Middle Atlas, the Marmoucha is characterized by the presence of various ...
Fatima Nassif, Abbès Tanji
openaire +2 more sources
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Geodesy and Geodynamics, 2019 We investigate sedimentological and tectonic processes at the central High Atlas, in order to understand their functioning and to build a geodynamic model that placed the area in its current geological frame.
Y. Timoulali +4 more
doaj +1 more source
ATLAS 1: Encountering Planet Earth [PDF]
Several NASA science programs examine the dynamic balance of sunlight, atmosphere, water, land, and life that governs Earth's environment. Among these is a series of Space Shuttle-Spacelab missions, named the Atmospheric Laboratory for Applications and ...
Accardi, Denise +5 more
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source