Results 151 to 153 of about 3,058 (153)

Abstract 744: Effective use of MDK/Midkine and MEK inhibitor to treat KRas mutated pulmonary adenocarcinoma cells

Cancer Research, 2014
Abstract Lung cancer is the leading cause of cancer-related mortality worldwide. Although a platinum-doublet regimen has become the standard of care, the benefit is modest and the 5-year survival rate has remained essentially unchanged over the past 3 decades. Recently, several molecular alterations have been defined as “driver mutations,
Takuya Fukazawa, Yutaka Maeda, Naomasa Ishida, Tomoki Yamatsuji, Munenori Takaoka, Minoru Haisa, Nagio Takigawa, Jeffery Whitsett, Yoshio Naomoto   +8 more
openaire   +1 more source

Disruption of the midkine gene (Mdk) resulted in altered expression of a calcium binding protein in the hippocampus of infant mice and their abnormal behaviour

Genes to Cells, 1998
Background:Midkine (MK) is a growth factor implicated in the development and repair of various tissues, especially neural tissues. However, its in vivo function has not been clarified.Results:Knockout mice lacking the MK gene (Mdk) showed no gross abnormalities.
E, Nakamura, K, Kadomatsu, S, Yuasa, H, Muramatsu, T, Mamiya, T, Nabeshima, Q W, Fan, K, Ishiguro, T, Igakura, S, Matsubara, T, Kaname, M, Horiba, H, Saito, T, Muramatsu   +13 more
openaire   +2 more sources

Chromosomal localization of two cell surface-associated molecules of potential importance in development: Midkine (Mdk) and basigin (Bsg)

Mammalian Genome, 1992
D, Simon-Chazottes, S, Matsubara, T, Miyauchi, T, Muramatsu, J L, Guénet   +4 more
openaire   +2 more sources