Midodrine for the early liberation from vasopressor support in the ICU (LIBERATE): a feasibility study [PDF]
Background Intravenous (IV) vasopressors are the mainstay of physiological support for hemodynamically unstable patients. However, the role of oral vasopressors remains unclear.
Sebastian J. Kilcommons +15 more
doaj +7 more sources
Midodrine and clinical outcomes in patients on maintenance hemodialysis [PDF]
Patients on hemodialysis often experience intradialytic hypotension (IDH), contributing to increased cardiovascular disease and mortality. Midodrine, an α-1 adrenergic receptor agonist, is commonly prescribed for IDH treatment or prevention. However, the
Junseok Jeon +6 more
doaj +3 more sources
A case report of midodrine to treat protein-losing enteropathy for heart transplant candidacy. [PDF]
Background Protein-losing enteropathy (PLE) is seen in up to 15% of patients with Fontan circulation and has important nutritional, immunologic, and haemodynamic consequences especially in the context of advanced heart failure.
Conte SM +3 more
europepmc +2 more sources
Need for Pretransplant Midodrine Does Not Negatively Impact Simultaneous Liver-kidney Transplant Outcomes [PDF]
Background. Midodrine is often needed pretransplant to improve hemodynamics in simultaneous liver-kidney transplant candidates. Previous research has shown that patients requiring midodrine before kidney transplant alone have increased posttransplant ...
Pranab M. Barman, MD +7 more
doaj +3 more sources
Midodrine initiation criteria, dose titration, and adverse effects when administered to treat shock: A systematic review and semi-quantitative analysis. [PDF]
Objective Systematically examine the literature describing midodrine to treat shock and to summarize current administration and dosing strategies. Data sources Structured literature search conducted in MEDLINE (PubMed) from inception through May 10, 2023.
Puissant MM +7 more
europepmc +2 more sources
Use of oral midodrine for weaning off norepinephrine in patients with septic shock
Background Early administration of norepinephrine in septic shock patients is linked to better survival rates. However, vasopressor dependence often occurs during the recovery phase, delaying ICU discharge. Objectives A comparative study was conducted on
Mohamed Obaya +3 more
doaj +2 more sources
Oral Midodrine as an Adjunct to Accelerate Vasopressor Liberation in Septic Shock: A Prospective Randomized Controlled Trial [PDF]
Introduction Septic shock is the most prevalent form of circulatory failure in critically ill patients, often necessitating prolonged vasopressor support to maintain adequate mean arterial pressure1.
ANAS V +5 more
europepmc +2 more sources
Midodrine and Weekly Albumin Therapy in Patients With Cirrhosis and Diuretic Intractable or Recurrent Ascites: A Case-Control Study. [PDF]
Background Overwhelming splanchnic and systemic vasodilatation and low mean arterial pressure (MAP) pose significant challenges in mobilizing ascites in patients with decompensated cirrhosis.
Borah GJ +5 more
europepmc +2 more sources
Use of Midodrine for Intraoperative Hemostasis in Cutaneous and Percutaneous Surgery [PDF]
Owing to the increasingly high volume of cutaneous and percutaneous procedures performed annually, the demand for local anesthesia has steadily risen. The gold-standard formulations for local anesthesia contain epinephrine at a concentration of 1:100,000
Joanna Dong +8 more
doaj +2 more sources
Background We aimed to evaluate the efficacy of midodrine as a prophylaxis against post-spinal hypotension in elderly patients undergoing hip arthroplasty.
Sarah Amin +7 more
doaj +2 more sources

