Results 1 to 10 of about 6,004 (277)

Oral midodrine for prophylaxis against post-spinal anesthesia hypotension during hip arthroplasty in elderly population: a randomized controlled trial [PDF]

BMC Anesthesiology
Background We aimed to evaluate the efficacy of midodrine as a prophylaxis against post-spinal hypotension in elderly patients undergoing hip arthroplasty.
Sarah Amin, Ahmed Hasanin, Rehab Mansour, Maha Mostafa, Dina Zakaria, Amany S Arafa, Akram Yassin, Hisham Ziada   +7 more
doaj   +5 more sources

Midodrine for the early liberation from vasopressor support in the ICU (LIBERATE): a feasibility study [PDF]

Pilot and Feasibility Studies
Background Intravenous (IV) vasopressors are the mainstay of physiological support for hemodynamically unstable patients. However, the role of oral vasopressors remains unclear.
Sebastian J. Kilcommons, Fadi Hammal, Dawn L. Opgenorth, Kirsten M. Fiest, Constantine J. Karvellas, Vincent I. Lau, Erika MacIntyre, Janek Senaratne, Jocelyn Slemko, Wendy Sligl, Fernando Zampieri, D.’Arcy Duquette, Lily T. Guan, Nadia Baig, Sean M. Bagshaw, Oleksa G. Rewa   +15 more
doaj   +3 more sources

Safety of midodrine in patients with heart failure with reduced ejection fraction: a retrospective cohort study [PDF]

Frontiers in Pharmacology
Background: Heart failure with reduced ejection fraction (HFrEF) poses significant health risks. Midodrine for maintaining blood pressure in HFrEF, requires further safety investigation.
Ming-Ju Wu, Ming-Ju Wu, Cheng-Hsu Chen, Cheng-Hsu Chen, Cheng-Hsu Chen, Cheng-Hsu Chen, Shang-Feng Tsai, Shang-Feng Tsai, Shang-Feng Tsai   +8 more
doaj   +3 more sources

Systemic reviews and meta-analysis of the use of midodrine in hepatorenal syndrome [PDF]

Romanian Medical Journal
Aims. This study analyzes the effectiveness of midodrine in reducing or managing Hepatorenal Syndrome (HRS). Design. A systematic review and meta-analysis were conducted to gather and assess relevant literature. The review included evaluating study aims,
Prem Balaji Reddy Lankapothu, Shrinidhi B., Satish Kumar M., Magesh Kumar S.   +3 more
doaj   +3 more sources

The Use of Midodrine as an Adjunctive Therapy to Liberate Patients from Intravenous Vasopressors: A Systematic Review and Meta-analysis of Randomized Controlled Studies

Cardiology and Therapy, 2023
Background Studies evaluating the role of midodrine as an adjunctive therapy to liberate patients with shock from intravenous (IV) vasopressors have yielded mixed results.
Mohamed Hamed, Sheref A. Elseidy, Ahmed Elkheshen, Jamal Maher, Adel Elmoghrabi, Ahmed Zaghloul, Andrew Panakos, Sidakpal Panaich, Marwan Saad, Ayman Elbadawi   +9 more
doaj   +2 more sources

Oral Midodrine Administration During the First 24 Hours of Sepsis to Reduce the Need of Vasoactive Agents: Placebo-Controlled Feasibility Clinical Trial

Critical Care Explorations, 2021
Objectives:. Our preliminary data and observational studies suggested an increasing “off label” use of oral midodrine as a vasopressor sparing agent in various groups of critically ill patients, including those with sepsis.
Amos Lal, MBBS, FACP, Vrinda Trivedi, MBBS, Mahrukh S. Rizvi, MD, Amy Amsbaugh, RRT, LRT, Melissa K Myers, MD, Khaled Saleh, MD, Rahul Kashyap, MBBS, MBA, Ognjen Gajic, MD, MSc, FCCP, FCCM   +7 more
doaj   +2 more sources

Hemodynamic Effects of an Increased Midodrine Dosing Frequency

Critical Care Explorations, 2021
Objectives:. In practice, midodrine has been used to reduce IV vasopressor requirements and decrease ICU length of stay. However, recent publications have failed to show clinical success when midodrine was administered every 8 hours.
Shea A. Macielak, PharmD, Nicholas J. Vollmer, PharmD, Natalie A. Haddad, PharmD, Christoph G. S. Nabzdyk, MD, Scott D. Nei, PharmD   +4 more
doaj   +4 more sources

Acute midodrine overdose: a case report [PDF]

Toxicology Communications, 2021
Midodrine is a prodrug metabolized to the peripheral acting alpha agonist desglymidodrine and is used to treat orthostatic hypotension. Reports of overdose are rare, consequently there is little guidance regarding treatment of overdose.
Jessica Peck, Steven D. Salhanick
doaj   +3 more sources

Exploring the Efficacy of Midodrine for Tapering Off Vasopressors. [PDF]

Cureus
Sepsis and septic shock represent critical conditions, often necessitating vasopressor support in the intensive care unit (ICU). Midodrine, an oral vasopressor, has gathered attention as a potential adjunct to vasopressor therapy, aiming to facilitate ...
Athar ZM, Arshad M, Shrivastava S.
europepmc   +2 more sources

Enteral Midodrine for Intravenous Vasopressor Weaning in Acute Traumatic Spinal Cord Injury Patients. [PDF]

Hosp Pharm
Background: Enteral vasopressor therapies have been used to facilitate the weaning of intravenous (IV) vasopressors in critically ill patients. Studies have shown mixed results in the medically critically ill population; however, this practice is still ...
Chau T, Colosimo C, Delic J, Igneri LA, Solomon D, Wang JL.   +5 more
europepmc   +2 more sources