Midodrine and clinical outcomes in patients on maintenance hemodialysis [PDF]
Scientific ReportsPatients on hemodialysis often experience intradialytic hypotension (IDH), contributing to increased cardiovascular disease and mortality. Midodrine, an α-1 adrenergic receptor agonist, is commonly prescribed for IDH treatment or prevention. However, the
Junseok Jeon +6 more
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Health Technology AssessmentBackground Orthostatic hypotension is a significant drop in blood pressure upon standing upright. It is very common and can result in symptoms such as postural dizziness, fainting and falls.
Helen Mossop +13 more
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Midodrine for the early liberation from vasopressor support in the ICU (LIBERATE): a feasibility study [PDF]
Pilot and Feasibility StudiesBackground Intravenous (IV) vasopressors are the mainstay of physiological support for hemodynamically unstable patients. However, the role of oral vasopressors remains unclear.
Sebastian J. Kilcommons +15 more
doaj +3 more sources
Midodrine and Weekly Albumin Therapy in Patients With Cirrhosis and Diuretic Intractable or Recurrent Ascites: A Case-Control Study. [PDF]
CureusBackground Overwhelming splanchnic and systemic vasodilatation and low mean arterial pressure (MAP) pose significant challenges in mobilizing ascites in patients with decompensated cirrhosis.
Borah GJ +5 more
europepmc +4 more sources
The Use of Midodrine as an Adjunctive Therapy to Liberate Patients from Intravenous Vasopressors: A Systematic Review and Meta-analysis of Randomized Controlled Studies [PDF]
Cardiology and Therapy, 2023 Background Studies evaluating the role of midodrine as an adjunctive therapy to liberate patients with shock from intravenous (IV) vasopressors have yielded mixed results.
Mohamed Hamed +9 more
doaj +2 more sources
Impact of Adjuvant Use of Midodrine to Intravenous Vasopressors: A Systematic Review and Meta-Analysis [PDF]
Critical Care Research and Practice, 2021 Purpose. To evaluate the efficacy and safety of midodrine use in intensive care units (ICU) to facilitate weaning off intravenous vasopressors (IVV). Methods.
Ahmad Al-Abdouh +9 more
doaj +2 more sources
Acute midodrine overdose: a case report [PDF]
Toxicology Communications, 2021 Midodrine is a prodrug metabolized to the peripheral acting alpha agonist desglymidodrine and is used to treat orthostatic hypotension. Reports of overdose are rare, consequently there is little guidance regarding treatment of overdose.
Jessica Peck, Steven D. Salhanick
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Efficacy of atomoxetine versus midodrine for neurogenic orthostatic hypotension [PDF]
Annals of Clinical and Translational Neurology, 2020 Objective The efficacy and safety of 1‐month atomoxetine and midodrine therapies were compared. Three‐month atomoxetine and combination therapies were investigated for additional benefits.
Jung‐Ick Byun +13 more
doaj +2 more sources
A case report of midodrine to treat protein-losing enteropathy for heart transplant candidacy. [PDF]
Eur Heart J Case RepBackground Protein-losing enteropathy (PLE) is seen in up to 15% of patients with Fontan circulation and has important nutritional, immunologic, and haemodynamic consequences especially in the context of advanced heart failure.
Conte SM +3 more
europepmc +2 more sources
Use of oral midodrine for weaning off norepinephrine in patients with septic shock
Egyptian Journal of Critical Care MedicineBackground Early administration of norepinephrine in septic shock patients is linked to better survival rates. However, vasopressor dependence often occurs during the recovery phase, delaying ICU discharge. Objectives A comparative study was conducted on
Mohamed Obaya +3 more
doaj +2 more sources