Results 1 to 10 of about 4,045 (199)
Hemodynamic Effects of an Increased Midodrine Dosing Frequency
Objectives: In practice, midodrine has been used to reduce IV vasopressor requirements and decrease ICU length of stay. However, recent publications have failed to show clinical success when midodrine was administered every 8 hours.
Christoph S. Nabzdyk+4 more
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Acute midodrine overdose: a case report [PDF]
AbstractMidodrine is a prodrug metabolized to the peripheral acting alpha agonist desglymidodrine and is used to treat orthostatic hypotension. Reports of overdose are rare, consequently there is little guidance regarding treatment of overdose. We report a case of toxicity following midodrine overdose and describe clinical findings and response to ...
Jessica Peck, Steven D. Salhanick
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Use of midodrine in heart failure: a review
Heart failure is a global health concern, affecting millions of individuals worldwide. Midodrine, an alpha-1 receptor agonist, might be a potential treatment option for patients with heart failure and concurrent hypotension. This review provides a comprehensive summary of the existing literature on the use of midodrine in heart failure patients ...
Gautam, Sudarshan+8 more
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Midodrine Efficacy in Orthostatic Hypotension [PDF]
To the Editors—We recently came across the review article by Parsaik et al. “Midodrine for Orthostatic Hypotension: A Systematic Review and Meta-Analysis of Clinical Trials” (J Gen Intern Med 28(11): 1496–503), and feel obligated to comment on several deficiencies of this work.
Robert D. Fealey+6 more
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Treatment of Orthostatic Hypotension with Midodrine and Octreotide1 [PDF]
The purpose of this study was to compare two treatments for orthostatic hypotension, midodrine (an alpha adrenergic agonist), and octreotide (an SRIH analogue) to each other and to combination therapy. Sixteen patients participated. Our hypothesis was that the 2 drugs together would be more effective than either drug alone.
Gabriella G. Horvath+3 more
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Idiopathic orthostatic hypotension, midodrine, and anaesthesia [PDF]
A patient with idiopathic orthostatic hypotension receiving chronic oral midodrine therapy required anaesthesia for coronary artery bypass grafting. A perioperative infusion of phenylephrine was substituted for midodrine, an alpha-2 agonist, enabling hypotension resulting from low systemic vascular resistance to be controlled easily.
P. J. Osborne, L. W. Lee
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Midodrine treatment for chronic fatigue syndrome [PDF]
Abstract The long term results of midodrine treatment in a patient having debilitating chronic fatigue syndrome (CFS) are reported. Midodrine treatment, directed at the autonomic nervous system, resulted in correction of the dysautonomia followed by improvement of fatigue.
J E Naschitz+3 more
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Midodrine: a role in the management of neurocardiogenic syncope [PDF]
To determine the benefit of midodrine, an alpha agonist, on symptom frequency and haemodynamic responses during head up tilt in patients with neurocardiogenic syncope.Cardiovascular investigation unit (a secondary and tertiary referral centre for the investigation and management of syncope).16 outpatients (mean (SD) age 56 (18) years; five men) with ...
J J Gilroy+3 more
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Treatment of Cirrhosis-Associated Hyponatremia with Midodrine and Octreotide [PDF]
Hyponatremia in the setting of cirrhosis is a common electrolyte disorder with few therapeutic options. The free water retention is due to non-osmotic vasopressin secretion resulting from the cirrhosis-associated splanchnic vasodilatation. Therefore, vasoconstrictive therapy may correct this electrolyte abnormality.
Minh-Kevin Nguyen+4 more
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Midodrine and the Ladder of Evidence to Climb [PDF]
Guruprasad P. Aithal+1 more
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