Midodrine and clinical outcomes in patients on maintenance hemodialysis [PDF]
Patients on hemodialysis often experience intradialytic hypotension (IDH), contributing to increased cardiovascular disease and mortality. Midodrine, an α-1 adrenergic receptor agonist, is commonly prescribed for IDH treatment or prevention. However, the
Junseok Jeon+6 more
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Need for Pretransplant Midodrine Does Not Negatively Impact Simultaneous Liver-kidney Transplant Outcomes [PDF]
Background. Midodrine is often needed pretransplant to improve hemodynamics in simultaneous liver-kidney transplant candidates. Previous research has shown that patients requiring midodrine before kidney transplant alone have increased posttransplant ...
Pranab M. Barman, MD+7 more
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Objectives:. Our preliminary data and observational studies suggested an increasing “off label” use of oral midodrine as a vasopressor sparing agent in various groups of critically ill patients, including those with sepsis.
Amos Lal, MBBS, FACP+7 more
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It is reasonable to treat patients with type 1 hepatorenal syndrome with midodrine and octreotide [PDF]
A critical appraisal and clinical application of Esrailian E, Pantangco ER, Kyulo NL, Hu KQ, Runyon BA. Octreotide/midodrine therapy significantly improves renal function and 30-day survival in patients with type 1 hepatorenal syndrome. Dig Dis Sci. 2007;
Kane, William
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Acute midodrine overdose: a case report [PDF]
Midodrine is a prodrug metabolized to the peripheral acting alpha agonist desglymidodrine and is used to treat orthostatic hypotension. Reports of overdose are rare, consequently there is little guidance regarding treatment of overdose.
Jessica Peck, Steven D. Salhanick
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Hemodynamic Effects of an Increased Midodrine Dosing Frequency
Objectives:. In practice, midodrine has been used to reduce IV vasopressor requirements and decrease ICU length of stay. However, recent publications have failed to show clinical success when midodrine was administered every 8 hours.
Shea A. Macielak, PharmD+4 more
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Use of Midodrine for Intraoperative Hemostasis in Cutaneous and Percutaneous Surgery [PDF]
Owing to the increasingly high volume of cutaneous and percutaneous procedures performed annually, the demand for local anesthesia has steadily risen. The gold-standard formulations for local anesthesia contain epinephrine at a concentration of 1:100,000
Joanna Dong+8 more
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Oral midodrine for prophylaxis against post-spinal anesthesia hypotension during hip arthroplasty in elderly population: a randomized controlled trial [PDF]
Background We aimed to evaluate the efficacy of midodrine as a prophylaxis against post-spinal hypotension in elderly patients undergoing hip arthroplasty.
Sarah Amin+7 more
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Midodrine for the early liberation from vasopressor support in the ICU (LIBERATE): a feasibility study [PDF]
Background Intravenous (IV) vasopressors are the mainstay of physiological support for hemodynamically unstable patients. However, the role of oral vasopressors remains unclear.
Sebastian J. Kilcommons+15 more
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Systemic reviews and meta-analysis of the use of midodrine in hepatorenal syndrome [PDF]
Aims. This study analyzes the effectiveness of midodrine in reducing or managing Hepatorenal Syndrome (HRS). Design. A systematic review and meta-analysis were conducted to gather and assess relevant literature. The review included evaluating study aims,
Prem Balaji Reddy Lankapothu+3 more
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