Results 1 to 10 of about 2,891 (156)

Impact of Adjuvant Use of Midodrine to Intravenous Vasopressors: A Systematic Review and Meta-Analysis [PDF]

Critical Care Research and Practice, 2021
Purpose. To evaluate the efficacy and safety of midodrine use in intensive care units (ICU) to facilitate weaning off intravenous vasopressors (IVV). Methods.
Ahmad Al-Abdouh, Sadam Haddadin, Atul Matta, Ahmad Jabri, Mahmoud Barbarawi, Waiel Abusnina, Qais Radideh, Mohammed Mhanna, Dante A. Suffredini, Erin D. Michos   +9 more
doaj   +2 more sources

Need for Pretransplant Midodrine Does Not Negatively Impact Simultaneous Liver-kidney Transplant Outcomes [PDF]

Transplantation Direct, 2021
Background. Midodrine is often needed pretransplant to improve hemodynamics in simultaneous liver-kidney transplant candidates. Previous research has shown that patients requiring midodrine before kidney transplant alone have increased posttransplant ...
Pranab M. Barman, MD, Lindsay Y. King, MD, Carl L. Berg, MD, Alice Parish, MSPH, Donna Niedzwiecki, PhD, Andrew S. Barbas, MD, Lisa McElroy, MD, Yuval A. Patel, MD   +7 more
doaj   +3 more sources

Oral Midodrine Administration During the First 24 Hours of Sepsis to Reduce the Need of Vasoactive Agents: Placebo-Controlled Feasibility Clinical Trial

Critical Care Explorations, 2021
Objectives:. Our preliminary data and observational studies suggested an increasing “off label” use of oral midodrine as a vasopressor sparing agent in various groups of critically ill patients, including those with sepsis.
Amos Lal, MBBS, FACP, Vrinda Trivedi, MBBS, Mahrukh S. Rizvi, MD, Amy Amsbaugh, RRT, LRT, Melissa K Myers, MD, Khaled Saleh, MD, Rahul Kashyap, MBBS, MBA, Ognjen Gajic, MD, MSc, FCCP, FCCM   +7 more
doaj   +2 more sources

Midodrine for the early liberation from vasopressor support in the ICU (LIBERATE): a feasibility study

Pilot and Feasibility Studies
Background Intravenous (IV) vasopressors are the mainstay of physiological support for hemodynamically unstable patients. However, the role of oral vasopressors remains unclear.
Sebastian J. Kilcommons, Fadi Hammal, Dawn L. Opgenorth, Kirsten M. Fiest, Constantine J. Karvellas, Vincent I. Lau, Erika MacIntyre, Janek Senaratne, Jocelyn Slemko, Wendy Sligl, Fernando Zampieri, D.’Arcy Duquette, Lily T. Guan, Nadia Baig, Sean M. Bagshaw, Oleksa G. Rewa   +15 more
doaj   +3 more sources

Treatment of prolonged clonidine-induced autonomic instability with midodrine: a case report about a new approach or a cautionary tale?

Emergency and Critical Care Medicine, 2023
. Background. Clonidine is a centrally acting α2 adrenergic and imidazoline-1 receptor agonist that can cause somnolence, bradycardia, and hypotension within several hours of ingestion.
Saada Malouf, Catherine Henry, Lara Pemberton, Joe-Anthony Rotella   +3 more
doaj   +2 more sources

LIBERATE: a study protocol for midodrine for the early liberation from vasopressor support in the intensive care unit (LIBERATE): protocol for a randomized controlled trial [PDF]

Trials, 2022
Background Intravenous (IV) vasopressors to support hemodynamics are a primary indication for intensive care unit (ICU) admission. Utilization of oral vasopressor therapy may offer an alternative to IV vasopressor therapy in the ICU, thus decreasing the ...
Dawn Opgenorth, Nadia Baig, Kirsten Fiest, Constantine Karvellas, Jim Kutsogiannis, Vincent Lau, Erika Macintyre, Janek Senaratne, Jocelyn Slemko, Wendy Sligl, Xiaoming Wang, Sean M. Bagshaw, Oleksa G. Rewa   +12 more
doaj   +2 more sources

Cough syncope treated with midodrine hydrochloride: one case report

Chinese Journal of Contemporary Neurology and Neurosurgery, 2020
DOI：10.3969/j.issn.1672⁃6731.2020.05 ...
Tao LIANG, Xiao⁃lin HU, Chang⁃ming WANG, Hong ZHU, Jing WU, Jun ZHANG   +5 more
doaj   +1 more source

Value of renal resistive index in hepatitis C virus related liver cirrhosis and its response to midodrine

The Egyptian Journal of Radiology and Nuclear Medicine, 2014
Background: Hyperdynamic circulatory state in liver cirrhosis is characterized by increased splanchnic blood flow and renal vasoconstriction. Aim: To evaluate the relationship between renal resistive indices (RI) and HCV liver cirrhosis severity and RI ...
Sameh Ahmed Abdel-bary, Eslam Safwat, Hany Ali Hussein, Ahmed Mohamed Hussein, Samer Malak Botros   +4 more
doaj   +2 more sources

Hemodynamic Effects of an Increased Midodrine Dosing Frequency

Critical Care Explorations, 2021
Objectives:. In practice, midodrine has been used to reduce IV vasopressor requirements and decrease ICU length of stay. However, recent publications have failed to show clinical success when midodrine was administered every 8 hours.
Shea A. Macielak, PharmD, Nicholas J. Vollmer, PharmD, Natalie A. Haddad, PharmD, Christoph G. S. Nabzdyk, MD, Scott D. Nei, PharmD   +4 more
doaj   +1 more source

Calcitonin gene-related peptide predicts therapeutic response to midodrine hydrochloride in children with vasovagal syncope

Frontiers in Neuroscience, 2022
The vasoconstriction agent midodrine hydrochloride is a vital treatment for pediatric patients diagnosed with vasovagal syncope (VVS), although the efficacy is variable.
Lintian Li, Huacai Zhao, Xiuxiu Ma, Fuyong Jiao, Jing Lin   +4 more
doaj   +1 more source