Results 1 to 10 of about 5,044 (233)

Midodrine and clinical outcomes in patients on maintenance hemodialysis [PDF]

Scientific Reports
Patients on hemodialysis often experience intradialytic hypotension (IDH), contributing to increased cardiovascular disease and mortality. Midodrine, an α-1 adrenergic receptor agonist, is commonly prescribed for IDH treatment or prevention. However, the
Junseok Jeon, Yu Jeong Lim, Bo Yeon Kim, Ji Young Choi, Jun Young Do, Jung Eun Lee, Seok Hui Kang   +6 more
doaj   +3 more sources

Oral midodrine for prophylaxis against post-spinal anesthesia hypotension during hip arthroplasty in elderly population: a randomized controlled trial [PDF]

BMC Anesthesiology
Background We aimed to evaluate the efficacy of midodrine as a prophylaxis against post-spinal hypotension in elderly patients undergoing hip arthroplasty.
Sarah Amin, Ahmed Hasanin, Rehab Mansour, Maha Mostafa, Dina Zakaria, Amany S Arafa, Akram Yassin, Hisham Ziada   +7 more
doaj   +3 more sources

Midodrine for the early liberation from vasopressor support in the ICU (LIBERATE): a feasibility study [PDF]

Pilot and Feasibility Studies
Background Intravenous (IV) vasopressors are the mainstay of physiological support for hemodynamically unstable patients. However, the role of oral vasopressors remains unclear.
Sebastian J. Kilcommons, Fadi Hammal, Dawn L. Opgenorth, Kirsten M. Fiest, Constantine J. Karvellas, Vincent I. Lau, Erika MacIntyre, Janek Senaratne, Jocelyn Slemko, Wendy Sligl, Fernando Zampieri, D.’Arcy Duquette, Lily T. Guan, Nadia Baig, Sean M. Bagshaw, Oleksa G. Rewa   +15 more
doaj   +3 more sources

Systemic reviews and meta-analysis of the use of midodrine in hepatorenal syndrome [PDF]

Romanian Medical Journal
Aims. This study analyzes the effectiveness of midodrine in reducing or managing Hepatorenal Syndrome (HRS). Design. A systematic review and meta-analysis were conducted to gather and assess relevant literature. The review included evaluating study aims,
Prem Balaji Reddy Lankapothu, Shrinidhi B., Satish Kumar M., Magesh Kumar S.   +3 more
doaj   +3 more sources

Oral Midodrine Administration During the First 24 Hours of Sepsis to Reduce the Need of Vasoactive Agents: Placebo-Controlled Feasibility Clinical Trial

Critical Care Explorations, 2021
Objectives:. Our preliminary data and observational studies suggested an increasing “off label” use of oral midodrine as a vasopressor sparing agent in various groups of critically ill patients, including those with sepsis.
Amos Lal, MBBS, FACP, Vrinda Trivedi, MBBS, Mahrukh S. Rizvi, MD, Amy Amsbaugh, RRT, LRT, Melissa K Myers, MD, Khaled Saleh, MD, Rahul Kashyap, MBBS, MBA, Ognjen Gajic, MD, MSc, FCCP, FCCM   +7 more
doaj   +2 more sources

Acute midodrine overdose: a case report [PDF]

Toxicology Communications, 2021
Midodrine is a prodrug metabolized to the peripheral acting alpha agonist desglymidodrine and is used to treat orthostatic hypotension. Reports of overdose are rare, consequently there is little guidance regarding treatment of overdose.
Jessica Peck, Steven D. Salhanick
doaj   +3 more sources

Hemodynamic Effects of an Increased Midodrine Dosing Frequency

Critical Care Explorations, 2021
Objectives:. In practice, midodrine has been used to reduce IV vasopressor requirements and decrease ICU length of stay. However, recent publications have failed to show clinical success when midodrine was administered every 8 hours.
Shea A. Macielak, PharmD, Nicholas J. Vollmer, PharmD, Natalie A. Haddad, PharmD, Christoph G. S. Nabzdyk, MD, Scott D. Nei, PharmD   +4 more
doaj   +4 more sources

Use of Midodrine for Intraoperative Hemostasis in Cutaneous and Percutaneous Surgery [PDF]

JID Innovations
Owing to the increasingly high volume of cutaneous and percutaneous procedures performed annually, the demand for local anesthesia has steadily risen. The gold-standard formulations for local anesthesia contain epinephrine at a concentration of 1:100,000
Joanna Dong, Naiem T. Issa, Michael Kaiser, Simonetta I. Gaumond, Michael Solis, Joel Gil, Robert S. Kirsner, Stephen C. Davis, Joaquin J. Jimenez   +8 more
doaj   +2 more sources

Use of oral midodrine for weaning off norepinephrine in patients with septic shock

Egyptian Journal of Critical Care Medicine
Background Early administration of norepinephrine in septic shock patients is linked to better survival rates. However, vasopressor dependence often occurs during the recovery phase, delaying ICU discharge. Objectives A comparative study was conducted on
Mohamed Obaya, Randa Soliman, Alia Abdelfattah, Moamen Arafa   +3 more
doaj   +2 more sources

Idiopathic orthostatic hypotension, midodrine, and anaesthesia [PDF]

Canadian Journal of Anaesthesia, 1991
A patient with idiopathic orthostatic hypotension receiving chronic oral midodrine therapy required anaesthesia for coronary artery bypass grafting. A perioperative infusion of phenylephrine was substituted for midodrine, an alpha-2 agonist, enabling hypotension resulting from low systemic vascular resistance to be controlled easily.
P. J. Osborne, L. W. Lee
openalex   +5 more sources