Results 1 to 10 of about 4,045 (199)

Hemodynamic Effects of an Increased Midodrine Dosing Frequency

open access: yesCritical Care Explorations, 2021
Objectives: In practice, midodrine has been used to reduce IV vasopressor requirements and decrease ICU length of stay. However, recent publications have failed to show clinical success when midodrine was administered every 8 hours.
Christoph S. Nabzdyk   +4 more
openaire   +5 more sources

Acute midodrine overdose: a case report [PDF]

open access: yesToxicology Communications, 2021
AbstractMidodrine is a prodrug metabolized to the peripheral acting alpha agonist desglymidodrine and is used to treat orthostatic hypotension. Reports of overdose are rare, consequently there is little guidance regarding treatment of overdose. We report a case of toxicity following midodrine overdose and describe clinical findings and response to ...
Jessica Peck, Steven D. Salhanick
openaire   +4 more sources

Use of midodrine in heart failure: a review

open access: yesAnnals of Medicine & Surgery, 2023
Heart failure is a global health concern, affecting millions of individuals worldwide. Midodrine, an alpha-1 receptor agonist, might be a potential treatment option for patients with heart failure and concurrent hypotension. This review provides a comprehensive summary of the existing literature on the use of midodrine in heart failure patients ...
Gautam, Sudarshan   +8 more
openaire   +3 more sources

Midodrine Efficacy in Orthostatic Hypotension [PDF]

open access: yesJournal of General Internal Medicine, 2014
To the Editors—We recently came across the review article by Parsaik et al. “Midodrine for Orthostatic Hypotension: A Systematic Review and Meta-Analysis of Clinical Trials” (J Gen Intern Med 28(11): 1496–503), and feel obligated to comment on several deficiencies of this work.
Robert D. Fealey   +6 more
openaire   +7 more sources

Treatment of Orthostatic Hypotension with Midodrine and Octreotide1 [PDF]

open access: yesThe Journal of Clinical Endocrinology & Metabolism, 1998
The purpose of this study was to compare two treatments for orthostatic hypotension, midodrine (an alpha adrenergic agonist), and octreotide (an SRIH analogue) to each other and to combination therapy. Sixteen patients participated. Our hypothesis was that the 2 drugs together would be more effective than either drug alone.
Gabriella G. Horvath   +3 more
openaire   +3 more sources

Idiopathic orthostatic hypotension, midodrine, and anaesthesia [PDF]

open access: yesCanadian Journal of Anaesthesia, 1991
A patient with idiopathic orthostatic hypotension receiving chronic oral midodrine therapy required anaesthesia for coronary artery bypass grafting. A perioperative infusion of phenylephrine was substituted for midodrine, an alpha-2 agonist, enabling hypotension resulting from low systemic vascular resistance to be controlled easily.
P. J. Osborne, L. W. Lee
openaire   +3 more sources

Midodrine treatment for chronic fatigue syndrome [PDF]

open access: yesPostgraduate Medical Journal, 2004
Abstract The long term results of midodrine treatment in a patient having debilitating chronic fatigue syndrome (CFS) are reported. Midodrine treatment, directed at the autonomic nervous system, resulted in correction of the dysautonomia followed by improvement of fatigue.
J E Naschitz   +3 more
openaire   +3 more sources

Midodrine: a role in the management of neurocardiogenic syncope [PDF]

open access: yesHeart, 1998
To determine the benefit of midodrine, an alpha agonist, on symptom frequency and haemodynamic responses during head up tilt in patients with neurocardiogenic syncope.Cardiovascular investigation unit (a secondary and tertiary referral centre for the investigation and management of syncope).16 outpatients (mean (SD) age 56 (18) years; five men) with ...
J J Gilroy   +3 more
openaire   +3 more sources

Treatment of Cirrhosis-Associated Hyponatremia with Midodrine and Octreotide [PDF]

open access: yesFrontiers in Medicine, 2017
Hyponatremia in the setting of cirrhosis is a common electrolyte disorder with few therapeutic options. The free water retention is due to non-osmotic vasopressin secretion resulting from the cirrhosis-associated splanchnic vasodilatation. Therefore, vasoconstrictive therapy may correct this electrolyte abnormality.
Minh-Kevin Nguyen   +4 more
openaire   +3 more sources

Midodrine and the Ladder of Evidence to Climb [PDF]

open access: yesJournal of Clinical and Experimental Hepatology, 2021
Guruprasad P. Aithal   +1 more
openaire   +3 more sources

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