Results 1 to 10 of about 3,592 (148)

Midodrine for the early liberation from vasopressor support in the ICU (LIBERATE): a feasibility study [PDF]

Pilot and Feasibility Studies
Background Intravenous (IV) vasopressors are the mainstay of physiological support for hemodynamically unstable patients. However, the role of oral vasopressors remains unclear.
Sebastian J. Kilcommons, Fadi Hammal, Dawn L. Opgenorth, Kirsten M. Fiest, Constantine J. Karvellas, Vincent I. Lau, Erika MacIntyre, Janek Senaratne, Jocelyn Slemko, Wendy Sligl, Fernando Zampieri, D.’Arcy Duquette, Lily T. Guan, Nadia Baig, Sean M. Bagshaw, Oleksa G. Rewa   +15 more
doaj   +4 more sources

Impact of Adjuvant Use of Midodrine to Intravenous Vasopressors: A Systematic Review and Meta-Analysis [PDF]

Critical Care Research and Practice, 2021
Purpose. To evaluate the efficacy and safety of midodrine use in intensive care units (ICU) to facilitate weaning off intravenous vasopressors (IVV). Methods.
Ahmad Al-Abdouh, Sadam Haddadin, Atul Matta, Ahmad Jabri, Mahmoud Barbarawi, Waiel Abusnina, Qais Radideh, Mohammed Mhanna, Dante A. Suffredini, Erin D. Michos   +9 more
doaj   +2 more sources

Midodrine and clinical outcomes in patients on maintenance hemodialysis [PDF]

Scientific Reports
Patients on hemodialysis often experience intradialytic hypotension (IDH), contributing to increased cardiovascular disease and mortality. Midodrine, an α-1 adrenergic receptor agonist, is commonly prescribed for IDH treatment or prevention. However, the
Junseok Jeon, Yu Jeong Lim, Bo Yeon Kim, Ji Young Choi, Jun Young Do, Jung Eun Lee, Seok Hui Kang   +6 more
doaj   +2 more sources

Oral Midodrine Administration During the First 24 Hours of Sepsis to Reduce the Need of Vasoactive Agents: Placebo-Controlled Feasibility Clinical Trial

Critical Care Explorations, 2021
Objectives:. Our preliminary data and observational studies suggested an increasing “off label” use of oral midodrine as a vasopressor sparing agent in various groups of critically ill patients, including those with sepsis.
Amos Lal, MBBS, FACP, Vrinda Trivedi, MBBS, Mahrukh S. Rizvi, MD, Amy Amsbaugh, RRT, LRT, Melissa K Myers, MD, Khaled Saleh, MD, Rahul Kashyap, MBBS, MBA, Ognjen Gajic, MD, MSc, FCCP, FCCM   +7 more
doaj   +2 more sources

Use of Midodrine for Intraoperative Hemostasis in Cutaneous and Percutaneous Surgery [PDF]

JID Innovations
Owing to the increasingly high volume of cutaneous and percutaneous procedures performed annually, the demand for local anesthesia has steadily risen. The gold-standard formulations for local anesthesia contain epinephrine at a concentration of 1:100,000
Joanna Dong, Naiem T. Issa, Michael Kaiser, Simonetta I. Gaumond, Michael Solis, Joel Gil, Robert S. Kirsner, Stephen C. Davis, Joaquin J. Jimenez   +8 more
doaj   +2 more sources

Treatment of prolonged clonidine-induced autonomic instability with midodrine: a case report about a new approach or a cautionary tale?

Emergency and Critical Care Medicine, 2023
. Background. Clonidine is a centrally acting α2 adrenergic and imidazoline-1 receptor agonist that can cause somnolence, bradycardia, and hypotension within several hours of ingestion.
Saada Malouf, Catherine Henry, Lara Pemberton, Joe-Anthony Rotella   +3 more
doaj   +2 more sources

LIBERATE: a study protocol for midodrine for the early liberation from vasopressor support in the intensive care unit (LIBERATE): protocol for a randomized controlled trial [PDF]

Trials, 2022
Background Intravenous (IV) vasopressors to support hemodynamics are a primary indication for intensive care unit (ICU) admission. Utilization of oral vasopressor therapy may offer an alternative to IV vasopressor therapy in the ICU, thus decreasing the ...
Dawn Opgenorth, Nadia Baig, Kirsten Fiest, Constantine Karvellas, Jim Kutsogiannis, Vincent Lau, Erika Macintyre, Janek Senaratne, Jocelyn Slemko, Wendy Sligl, Xiaoming Wang, Sean M. Bagshaw, Oleksa G. Rewa   +12 more
doaj   +2 more sources

Control, Fludrocortisone or Midodrine for the treatment of Orthostatic Hypotension (CONFORM-OH): results from an internal pilot randomised controlled trial. [PDF]

Pilot Feasibility Stud
Mossop H, Al-Ashmori S, Sotire T, Clark E, Watson G, Witham MD, Vale L, McGregor N, Phillipson J, Wason JMS, Yarnall AJ, Parry S, Hancock H, Kenny RA, Frith J.   +14 more
europepmc   +6 more sources

Cough syncope treated with midodrine hydrochloride: one case report

Chinese Journal of Contemporary Neurology and Neurosurgery, 2020
DOI：10.3969/j.issn.1672⁃6731.2020.05 ...
Tao LIANG, Xiao⁃lin HU, Chang⁃ming WANG, Hong ZHU, Jing WU, Jun ZHANG   +5 more
doaj   +1 more source

Value of renal resistive index in hepatitis C virus related liver cirrhosis and its response to midodrine

The Egyptian Journal of Radiology and Nuclear Medicine, 2014
Background: Hyperdynamic circulatory state in liver cirrhosis is characterized by increased splanchnic blood flow and renal vasoconstriction. Aim: To evaluate the relationship between renal resistive indices (RI) and HCV liver cirrhosis severity and RI ...
Sameh Ahmed Abdel-bary, Eslam Safwat, Hany Ali Hussein, Ahmed Mohamed Hussein, Samer Malak Botros   +4 more
doaj   +2 more sources