Results 1 to 10 of about 3,441 (189)

Need for Pretransplant Midodrine Does Not Negatively Impact Simultaneous Liver-kidney Transplant Outcomes [PDF]

Transplantation Direct, 2021
Background. Midodrine is often needed pretransplant to improve hemodynamics in simultaneous liver-kidney transplant candidates. Previous research has shown that patients requiring midodrine before kidney transplant alone have increased posttransplant ...
Pranab M. Barman, MD, Lindsay Y. King, MD, Carl L. Berg, MD, Alice Parish, MSPH, Donna Niedzwiecki, PhD, Andrew S. Barbas, MD, Lisa McElroy, MD, Yuval A. Patel, MD   +7 more
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Midodrine and clinical outcomes in patients on maintenance hemodialysis [PDF]

Scientific Reports
Patients on hemodialysis often experience intradialytic hypotension (IDH), contributing to increased cardiovascular disease and mortality. Midodrine, an α-1 adrenergic receptor agonist, is commonly prescribed for IDH treatment or prevention. However, the
Junseok Jeon, Yu Jeong Lim, Bo Yeon Kim, Ji Young Choi, Jun Young Do, Jung Eun Lee, Seok Hui Kang   +6 more
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Impact of COVID‑19 infection on subsequent prescriptions of autonomic dysfunction pharmacotherapy: a nationwide propensity‑score‑matched Cohort study in Japan [PDF]

Annals of Medicine
Background Autonomic dysfunction, including orthostatic hypotension and postural tachycardia syndrome, has emerged as a COVID-19 complication.
Daisuke Miyamori, Masanori Ito
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Midodrine for Sepsis Treatment and Early Vasopressor Weaning (MID-STEP): protocol for a pragmatic randomised clinical trial [PDF]

BMJ Open
Introduction Sepsis is a global health priority with nearly 50 million cases annually. Cardiovascular dysfunction is common, frequently manifesting as hypotension that persists despite fluid resuscitation.
Amos Lal, Rodrigo Cartin-Ceba, Vikas Bansal, Devang Sanghavi, Ognjen Gajic, Aryan Shiari, Erin F Barreto, Aysun Tekin, Gabriele Halpern, Diksha Gowda, Amy Schuchard, Anes Joguncic, Phillip Schulte, Yewande E Odeyemi, Sumera Ahmad, Bo Madsen, Zeeshan Rizwan, Swetha Reddy, Vatsa Bhavsar, Juan Pablo Domecq Garces, Syed Anjum Khan   +20 more
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Midodrine hydrochloride Form A, C12H19N2O4+·Cl− [PDF]

Acta Crystallographica Section E: Crystallographic Communications
The crystal structure of midodrine hydrochloride Form A (systematic name: {[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]carbamoyl}methanaminium chloride, C12H19N2O4+·Cl−) has been solved and refined using synchrotron X-ray powder diffraction data, and ...
Jacob K. Salazar, James A. Kaduk, Anja Dosen, Thomas N. Blanton   +3 more
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Reversible cerebral vasoconstriction syndrome following ciltacabtagene autoleucel therapy for relapsed multiple myeloma: a case report [PDF]

Frontiers in Immunology
Ciltacabtagene autoleucel (cilta-cel), a BCMA-directed CAR-T therapy, is approved for relapsed/refractory multiple myeloma (RRMM). Cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS) are common, but ...
Tuan L. Phan, Adel Hijazi, Romi Xi, Mohamed Ridha, Tirisham V. Gyang, Monica Sarkar, Mohammad Shujaat, Shahid Nimjee, Andrew Slivka, Mhd Ezzat Zaghlouleh, Allison Jordan, James S. Blachly, Jonathan Brammer, Evandro Bezerra, Naresh Bumma, Don Benson, Elvira Umyarova, Abdullah Khan, Srinivas Devarakonda, Francesca Cottini, Ashley E. Rosko   +20 more
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Control, Fludrocortisone or Midodrine for the treatment of Orthostatic Hypotension: CONFORM-OH pilot RCT and economic evaluation

Health Technology Assessment
Background Orthostatic hypotension is a significant drop in blood pressure upon standing upright. It is very common and can result in symptoms such as postural dizziness, fainting and falls.
Helen Mossop, Sarah Al Ashmori, Tumi Sotire, Emma Clark, Gillian Watson, Miles Witham, Luke Vale, Naomi McGregor, Julia Phillipson, James MS Wason, Alison J Yarnall, Helen Hancock, Rose Anne Kenny, James Frith   +13 more
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The effects of midodrine on patients with liver cirrhosis and refractory ascites: a randomized controlled trial [PDF]

African Journal of Gastroenterology and Hepatology, 2023
Background: Splanchnic vasodilation is a significant contributor to the development of ascites in cirrhotic patients. So, midodrine, an alpha-one agonist, may improve circulatory abnormality in cirrhotic patients via its vasoconstrictive action, thus ...
Essam Aboelnasr, Sahar Elyamani, Amira Ahmed, Samah Soliman   +3 more
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Hemodynamic Effects of an Increased Midodrine Dosing Frequency

Critical Care Explorations, 2021
Objectives:. In practice, midodrine has been used to reduce IV vasopressor requirements and decrease ICU length of stay. However, recent publications have failed to show clinical success when midodrine was administered every 8 hours.
Shea A. Macielak, PharmD, Nicholas J. Vollmer, PharmD, Natalie A. Haddad, PharmD, Christoph G. S. Nabzdyk, MD, Scott D. Nei, PharmD   +4 more
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Calcitonin gene-related peptide predicts therapeutic response to midodrine hydrochloride in children with vasovagal syncope

Frontiers in Neuroscience, 2022
The vasoconstriction agent midodrine hydrochloride is a vital treatment for pediatric patients diagnosed with vasovagal syncope (VVS), although the efficacy is variable.
Lintian Li, Huacai Zhao, Xiuxiu Ma, Fuyong Jiao, Jing Lin   +4 more
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