Results 11 to 20 of about 13,742 (189)

Outpatient cervical ripening with Foley balloon or mifepristone: Insights into the time taken to reach the active phase of labor. [PDF]

open access: yesInt J Gynaecol Obstet
Abstract Objective To estimate the median time elapsed between the start of cervical ripening and the diagnosis of the active phase of labor, according to maternal and pregnancy characteristics, in low‐risk pregnancies submitted to outpatient cervical ripening with a Foley balloon catheter or oral mifepristone.
Carvalho-Afonso M   +3 more
europepmc   +2 more sources

Trends in medication abortion and the role of low-volume and nonmetropolitan mifepristone purchasers: 2008–2011 and 2014–2017

open access: yesContraception: X, 2020
Objective: The objective was to examine trends in the number of low-volume and nonmetropolitan mifepristone purchasers and their role in the expansion of medication abortion. Methods: We use deidentified data from Danco Laboratories, the sole distributor
Rachel K. Jones
doaj   +1 more source

Clinical management of patients with Cushing syndrome treated with mifepristone: consensus recommendations

open access: yesClinical Diabetes and Endocrinology, 2020
Background While surgery is the first-line treatment for patients with endogenous hypercortisolism (Cushing syndrome [CS]), mifepristone has been shown to be a beneficial medical treatment option, as demonstrated in the SEISMIC (Study of the Efficacy and
David R. Brown   +9 more
doaj   +1 more source

The effects of mifepristone on the structure of human decidua and chorion and Bax and Bcl-2 expression at early stage of pregnancy

open access: yesBMC Pharmacology and Toxicology, 2022
Background As a progesterone receptor antagonist, mifepristone combined with misoprostol is widely used to terminate early pregnancy in clinical practice.
Fei Tian   +7 more
doaj   +1 more source

Mifepristone Directly Disrupts Mouse Embryonic Development in Terms of Cellular Proliferation and Maturation In Vitro

open access: yesToxics, 2021
Mifepristone (RU-486), a synthetic steroid with potent antiprogestogen and anti-glucocorticoid properties, has been widely used in clinical practice. Its effect on the endometrium, ovary, and fallopian tube has been well reported in many human and animal
Yu-Ting Su   +5 more
doaj   +1 more source

Pharmacist direct dispensing of mifepristone for medication abortion in Canada: a survey of community pharmacists

open access: yesBMJ Open, 2022
Introduction Pharmacists were acknowledged as the most appropriate healthcare professional to dispense mifepristone for medication abortion shortly after the prescription therapy became available in January 2017 in Canada.Objective We aimed to identify ...
Wendy V Norman   +3 more
doaj   +1 more source

Determination of Mifepristone (RU-486) and Its Metabolites in Maternal Blood Sample after Pharmacological Abortion

open access: yesMolecules, 2022
The aim of the study was the development and validation of the UHPLC-QqQ-MS/MS method for the determination of mifepristone in human blood as well as the identification and quantification of its metabolites after self-induced pharmacological abortion ...
Paweł Szpot   +3 more
doaj   +1 more source

Mifepristone Treatment in Pregnant Murine Model Induced Mammary Gland Dysplasia and Postpartum Hypogalactia

open access: yesFrontiers in Cell and Developmental Biology, 2020
Mammary gland dysplasia and postpartum hypogalactia often occur in humans and in the livestock breeding industry. However, their underlying mechanisms are not clear yet.
Hongmei Zhu   +7 more
doaj   +1 more source

Optimized pharmacological control over the AAV-Gene-Switch vector for regulable gene therapy

open access: yesMolecular Therapy: Methods & Clinical Development, 2021
Gene therapy in its current design is an irreversible process. It cannot be stopped in case of unwanted side effects, nor can expression levels of therapeutics be adjusted to individual patient’s needs.
Shi Cheng   +4 more
doaj   +1 more source

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