Results 41 to 50 of about 13,742 (189)

Mifepristone Followed by Misoprostol Compared with Placebo Followed by Misoprostol as Medical Treatment for Early Pregnancy Loss (the Triple M trial): A Double-Blind Placebo-Controlled Randomised Trial

Fertility & Reproduction, 2022
Background: Worldwide, millions of women seek treatment for early pregnancy loss (EPL) annually. Medical management with misoprostol is widely used, but only effective 60% of the time.
Charlotte HAMEL, Sjors COPPUS, Joyce VAN DEN BERG, Esther HINK, Jacoba VAN SEETERS, Paul VAN KESTEREN, Ashley MERIEN, Bas TORRENGA, Rafli VAN DE LAAR, Josien Terwisscha VAN SCHELTINGA, Ingrid GAUGLER-SENDEN, Peppino GRAZIOSI, Minouche VAN RUMSTE, Ewka NELISSEN, Frank VANDENBUSSCHE, Marcus SNIJDERS   +15 more
doaj   +1 more source

Glucocorticoids and HPA axis regulation in the stress–obesity connection: A comprehensive overview of biological, physiological and behavioural dimensions

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton, Myrte Schoenmakers, Brenda W. J. H. Penninx, Mariëtte R. Boon, Elisabeth F. C. van Rossum   +4 more
wiley   +1 more source

The Knowledge, Attitudes and Practices of Practice Nurses in the Provision of Medication Abortion: A Cross‐Sectional Survey

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To examine practice nurse knowledge, attitudes, and practices about medication abortion in Australia. Design Cross‐sectional survey. Methods A national online survey was conducted from July to December 2021. Nurses working in general practice were recruited using convenience sampling.
Sharon James, Satish Melwani, Stella May Gwini, Kirsten I. Black, Angela Taft, Deborah Bateson, Wendy V. Norman, Danielle Mazza   +7 more
wiley   +1 more source

Use of mifepristone in preparation of uterine cervix for delivery

Медицинский совет, 2013
The effectiveness of mifepristone in the preparation of cervix uteri to delivery was evaluated. Data on pregnancy, delivery and perinatal outcomes in 120 women with full-term births was analyzed. Mifepristone was most efficient in patients with Bishop's
V. A. Petrukhin, T. S. Kovalenko, K. N. Akhvlediani, M. V. Kapustina, E. V. Magilevskaya   +4 more
doaj   +1 more source

Mifepristone therapy in symptomatic leiomyomata using a variable dose pattern with a favourable outcome

Journal of Mid-Life Health, 2018
Background: Leiomyomata causing symptoms have a deleterious effect on the health of women during reproductive age. Mifepristone, a progesterone antagonist was studied for reduction of symptoms in leiomyomata in perimenopausal women. Material and Methods:
Deepti Jain
doaj   +1 more source

Educating Midwives as Abortion Providers: Implementing Innovative Models for Standardized Training in Abortion Care

Journal of Midwifery &Women's Health, EarlyView.
Abstract The Dobbs v Jackson Women's Health Organization US Supreme Court decision significantly limited patients' access to abortion services, and the providers who can legally deliver this care. Currently 22 states license providers other than physicians to provide medication or procedural abortion.
Nicole Quinones, Samantha Auerbach, Nikki Lanshaw, Nikia Grayson, Julie Blumenfeld, Becca Neuwirth, Pamela Pearson, Ellen Chaney Solis, Robyn Nisi, Kylea L. Liese   +9 more
wiley   +1 more source

Development of specific glucocorticoid receptor antagonists

European Journal of Psychotraumatology, 2012
Background / Methods : Mifepristone, a potent glucocorticoid receptor (GR) and progesterone receptor (PR) antagonist, has recently become the first medication approved for the treatment of Cushing's syndrome, the archetypal illness of cortisol ...
Joseph K. Belanoff
doaj   +1 more source

Oxycodone alleviates mifepristone‐stimulated human endometrial stromal cell injury by activating the Keap1/Nrf2/HO‐1 signaling pathway

Immunity, Inflammation and Disease, 2023
Background Endometrial injury is a common disease in women caused by intrauterine inflammation, infections, and endocrine disorders. Human endometrial stromal cells (hEndoSCs) can maintain endometrial homeostasis and play an important role in repairing ...
Aibing Zhu, Fei Yao, Mingkun Shen
doaj   +1 more source

“Just Stay Home and Wait It Out”: Exploring Challenges Accessing Care for Miscarriage in Indiana

Perspectives on Sexual and Reproductive Health, EarlyView.
ABSTRACT Introduction Qualitative research on miscarriage in the United States primarily draws on the experiences of participants recruited from healthcare settings which may fail to robustly illuminate how people navigate to care. We aimed to explore the miscarriage experiences of Indiana residents, identify barriers to access, and generate ...
Kathryn J. LaRoche, Anayra Maldonado Quiles, Oluwapamimo J. Fafowora, Fatimah Lawal   +3 more
wiley   +1 more source

C‐X‐C chemokine receptor CXCR4 mediates diurnal changes in the aggregation and dispersion of CD8+ T cells within the tumor microenvironment

International Journal of Cancer, Volume 158, Issue 6, Page 1740-1754, 15 March 2026.
What's new? In addition to governing daily variations in biological activity, the circadian clock regulates immune cell migration into tumors. Whether this influence extends to immune cell localization within the tumor microenvironment (TME) is unknown. Here, using cell and animal models, the authors investigated immune cell distribution within the TME
Akito Tsuruta, Marina Fujimoto, Yasuha Hiraoka, Aoi Taniguchi, Yuki Shiiba, Takuto Inoki, Tomoaki Yamauchi, Yuya Yoshida, Naoya Matsunaga, Shigehiro Ohdo, Satoru Koyanagi   +10 more
wiley   +1 more source