Results 111 to 120 of about 474,198 (345)

Advanced Oral Delivery Systems for Nutraceuticals

Advanced Healthcare Materials, EarlyView.
Emerging delivery technologies are explored to overcome barriers to oral nutraceutical absorption. Traditional carriers are compared with novel platforms including biodegradable polymers, MOFs, MPNs, and 3D printing. These systems enhance bioavailability, control release, and enable personalized nutrition.
Xin Yang, Linzixuan Zhang, Zhiling Zheng, Robert Langer, Ana Jaklenec   +4 more
wiley   +1 more source

Regional metabolic patterns in mild cognitive impairment and Alzheimer’s disease [PDF]

, 2000
Kejal Kantarci, Clifford R. Jack, Yun Xu, Norberg G. Campeau, Peter C. O’Brien, Glenn E. Smith, Robert J. Ivnik, Bradley F. Boeve, E. Kokmen, Eric G. Tangalos, R. C. Petersen   +10 more
openalex   +1 more source

Functional hubs in mild cognitive impairment [PDF]

, 2015
We investigate how hubs of functional brain networks are modified as a result of mild cognitive impairment (MCI), a condition causing a slight but noticeable decline in cognitive abilities, which sometimes precedes the onset of Alzheimer's disease.
Bajo Breton, Ricardo, Boccaletti, Stefano, Buldú, J.M., Gil, Pablo, Maestú, Fernando, Navas Santo-Tomas, Adrian, Papo, David, Pozo Guerrero, Francisco del, Sendiña Nadal, Irene   +8 more
core   +2 more sources

Redox‐Active Polyphenol Red Molecularly Imprinted Polymers on Porous Gold Electrodes for Ultrasensitive, AI‐Assisted Detection of Alzheimer's Biomarkers in Undiluted Biofluids

Advanced Healthcare Materials, EarlyView.
This work presents a low‐cost, reagent‐free point‐of‐care biosensor integrating redox‐active polyphenol red molecularly imprinted polymers (pPhR MIPs) on highly porous gold (HPG) electrodes for ultrasensitive detection of phosphorylated tau 181 (p‐Tau 181), an Alzheimer’s disease biomarker, in undiluted biofluids.
Sudhaunsh Deshpande, Ajith Mohan Arjun, Guoyi Liu, Kryztof Pawlak, Sanjiv Sharma   +4 more
wiley   +1 more source

Network Structure of Depressive Symptomatology in Elderly with Cognitive Impairment

Medicina
Objective and objectives: Patients with cognitive disorders such as Alzheimer’s disease (AD) and mild cognitive impairment (MCI) frequently exhibit depressive symptoms. Depressive symptoms can be evaluated with various measures and questionnaires.
Jeehyung Pyo, Hyukjun Lee, Jakyung Lee, Daseul Lee, Hyeona Yu, Shinn-Won Lim, Woojae Myung, Doh-Kwan Kim   +7 more
doaj   +1 more source

Spontaneous speech based web screening test for MCI. [PDF]

, 2014
Background / Aim Even today there is a great diagnostic uncertainty in the prodromal stages of Alzheimer’s disease (AD). Our recent effort has focused on the very earliest detectable indicators of cognitive decline in mild cognitive impairment (MCI ...
Hegyi, Ágnes, Hoffmann, Ildikó, Kálmán, János, Pákáski, Magdolna, Szatlóczki, Gréta   +4 more
core  

Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics

Advanced Materials, EarlyView.
Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi, Yadi Fan, Qin Zhang, Yingying Huang, Mo Yang   +4 more
wiley   +1 more source

Linear and Symmetric Artificial Synapses Driven by Hydrogen Bonding for Accurate and Reliable Neuromorphic Computing

Advanced Materials, EarlyView.
Hydrogen‐bond‐driven interface engineering enables highly linear and symmetric artificial synapses based on CsPbI3–PVA hybrids. This strategy suppresses trap states and guides directional ion migration, yielding stable optoelectronic plasticity. The devices achieve ultralow power operation and human‐like learning in neuromorphic networks, offering a ...
Min Jong Lee, Sang Heon Lee, Dong Gyu Lee, Tae Hyuk Kim, Yubhin Cho, Gyeong Min Lee, Sung Su Yoon, Seon Joong Kim, Hyungju Ahn, Tae Kyung Lee, Jae Won Shim   +10 more
wiley   +1 more source

Practice parameter: Early detection of dementia: Mild cognitive impairment (an evidence-based review) [RETIRED] [PDF]

, 2001
Ronald C. Petersen, J E Stevens, Mary Ganguli, Eric G. Tangalos, Jeffrey L. Cummings, Steven T. DeKosky   +5 more
openalex   +1 more source

Lithium‐Charged Gold Nanoparticles: A New Powerful Tool for Lithium Delivery and Modulation of Glycogen Synthase Kinase 3 Activity

Advanced Materials, EarlyView.
This study introduces glutathione‐stabilized gold nanoparticles for targeted lithium delivery (LiG‐AuNPs), enabling the controlled modulation of Glycogen Synthase Kinase‐3 (GSK‐3β). These non‐toxic, 2‐nm particles release lithium intracellularly, effectively inhibiting GSK‐3β in the brain without significant plasma lithium alterations.
Antonio Buonerba, Giulia Puliatti, Domenica Donatella Li Puma, Bruno Bandiera, Beatrice Cannata, Maria Elena Marcocci, Nicolina Castagno, Irene Contento, Salvatore Impemba, Mariarosa Scognamiglio, Rocco Di Girolamo, Vincenzo Naddeo, Patrizia Canton, Carmine Capacchione, Laura Sposito, Martina Albini, Francesco Pastore, Silvia Baroni, Alfonso Grassi, Claudio Grassi, Roberto Piacentini   +20 more
wiley   +1 more source