Results 171 to 180 of about 772,479 (371)

The diagnosis of mild cognitive impairment due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

Alzheimer's & Dementia, 2011
M. Albert, S. DeKosky, D. Dickson, B. Dubois, H. Feldman, Nick C Fox, A. Gamst, D. Holtzman, W. Jagust, R. Petersen, P. Snyder, M. Carrillo, B. Thies, C. Phelps   +13 more
semanticscholar   +1 more source

Bidirectional Interaction Between the Brain and Bone in Traumatic Brain Injury

Advanced Science, EarlyView.
Traumatic brain injury (TBI) disrupts the blood–brain barrier and activates neuroimmune responses, causing metabolic disturbances and long‐term bone mass loss. Concurrent fractures accelerate healing and enhance osteogenesis but disrupt regulatory mechanisms, leading to altered bone dynamics and exacerbating neuroinflammation, complicating recovery ...
Wei Zhang, Jun Zou, Lingli Zhang
wiley   +1 more source

Preventing disability in older adults with mild cognitive impairment: A Strategy Training intervention study

Contemporary Clinical Trials Communications, 2019
Non-pharmacological interventions designed to change cognitive function in older adults with Mild Cognitive Impairment have shown mixed results. Few studied interventions directly address preclinical disability. Slowing changes in disability are critical
Juleen Rodakowski, Katlyn W. Golias, Charles F. Reynolds, III, Meryl A. Butters, Oscar L. Lopez, Mary Amanda Dew, Elizabeth R. Skidmore   +6 more
doaj  

Screening algorithm for predementia cognitive impairment in cardiovascular patients at a general practitioner's appointment. Expert Consensus Statement

Кардиоваскулярная терапия и профилактика
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O. M. Drapkina, S. A. Berns, S. Yu. Nikulina, E. Yu. Solovieva   +3 more
doaj   +1 more source

Challenging assumptions about Alzheimer's disease: Mild cognitive impairment and the cholinergic hypothesis [PDF]

, 2002
John C. Morris
openalex   +1 more source

Mild cognitive impairment as a diagnostic entity

Journal of Internal Medicine, 2004
R. Petersen
semanticscholar   +1 more source

Sleep Deprivation Activates a Conserved Lactate‐H3K18la‐RORα Axis Driving Neutrophilic Inflammation Across Species

Advanced Science, EarlyView.
Sleep deprivation triggers systemic immune activation characterized by neutrophil accumulation and cytokine release. This study reveals a conserved metabolic‒epigenetic mechanism whereby lactate‐induced H3K18 lactylation upregulates RORα expression, promoting neutrophilic inflammation.
Ren Zhou, Keyun Li, Xiezong Hu, Shuhao Fan, Yuxuan Gao, Xiaoshu Xue, Yu Bu, Haoyi Zhang, Yili Wang, Chunjiao Wei, Shangrong Zhang, Zhongwen Xie, Chao Liu, Peng Chen, Zongjun Yin, Dalong Ren   +15 more
wiley   +1 more source

Modeling Big Medical Survival Data Using Decision Tree Analysis with Apache Spark [PDF]

, 2019
In many medical studies, an outcome of interest is not only whether an event occurred, but when an event occurred; and an example of this is Alzheimer’s disease (AD).
Abdelqader, Ikhlas, Alsaedi, Abdalrahman, Altaie, Khulud, Delano, Mohammed Niaz, Fong, Alvis   +4 more
core   +1 more source

A Systematic Computational Framework for Practical Identifiability Analysis in Mathematical Models Arising from Biology

Advanced Science, EarlyView.
A systematic computational framework is developed for practical identifiability analysis in biological models. The framework establishes a rigorous definition, introduces efficient coordinate‐based identifiability metrics, and proposes novel regularization strategies.
Shun Wang, Wenrui Hao
wiley   +1 more source

Mild cognitive impairment: prevalence and incidence according to different diagnostic criteria: Results of the Leipzig Longitudinal Study of the Aged (LEILA75+) [PDF]

, 2003
Anja Busse, Jeannette Bischkopf, Steffi G. Riedel‐Heller, M C Angermeyer   +3 more
openalex   +1 more source