Results 51 to 60 of about 474,198 (345)

Clinical Characteristics of Parkinsonism in HTLV‐1‐Associated Myelopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Human T‐lymphotropic virus type 1 (HTLV‐1)‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) is the classic neurological manifestation of HTLV‐1 infection; however, this virus has also been associated with other neurological disorders. Concurrent parkinsonism is relatively rare and presents diagnostic challenges.
Mika Dozono, Satoshi Nozuma, Shota Hirakata, Takashi Yoshida, Daisuke Kodama, Masakazu Tanaka, Eiji Matsuura, Ryuji Kubota, Hiroshi Takashima   +8 more
wiley   +1 more source

Application of Deep Learning in Classification and Diagnosis of Mild Cognitive Impairment [PDF]

Jisuanji kexue yu tansuo
Alzheimer's disease is an irreversible neurodegenerative disease that has not been completely cured, but its progression can be delayed by early intervention. Mild cognitive impairment is the initial stage of Alzheimer??s disease.
ZHOU Qixiang, WANG Xiaoyan, ZHANG Wenkai, HE Xin
doaj   +1 more source

Understanding Mechanisms of Whole Brain and Regional Grey Matter Atrophy in Children With MOGAD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the mechanisms driving whole brain and regional grey matter (GM) volume changes along with their clinical correlates in paediatric myelin oligodendrocyte glycoprotein antibody (MOG‐Ab)–associated disease (MOGAD). Methods One‐hundred‐nine paediatric MOGAD patients from two UK centres underwent MRI at attack nadir and ...
Ermelinda De Meo, Riccardo Nistri, Michael Eyre, Cheryl Hemingway, Ming Lim, Thomas Rossor, Asthik Biswas, Kshitij Mankad, Ata Siddiqui, Sniya Sudhakar, Declan Chard, Frederik Barkhof, Arman Eshaghi, Olga Ciccarelli, Yael Hacohen   +14 more
wiley   +1 more source

Cognitive function in patients undergoing cystectomy for bladder cancer – results from a prospective observational study

Therapeutic Advances in Urology, 2022
Background: Impaired cognitive function of bladder cancer patients plays a role in coping with the kind of urinary diversion and may impact perioperative morbidity. In this study we therefore aimed to assess the prevalence of mild cognitive impairment in
Camilla M. Grunewald, Vera Feldmeier, Tillmann Supprian, Peter Albers, Markus Giessing, Günter Niegisch   +5 more
doaj   +1 more source

Cognitive Resilience in Apolipoprotein ε4 Carrier Women Predicted by Neuron‐Derived Extracellular Vesicles

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Apolipoprotein (APOE) ε4 allele is the strongest genetic risk factor for late‐onset Alzheimer's disease (AD); however, many ε4 carriers remain cognitively intact into old age. Leveraging plasma neuron‐derived extracellular vesicles (NDEVs), we sought to identify biomarkers of cognitive resilience and their interplay with APOE ...
Apostolos Manolopoulos, Maja Mustapic, Carlos Nogueras‐Ortiz, Francheska Delgado‐Peraza, Krishna A. Pucha, Pamela J. Yao, Joseph Blommer, Michael P. Vreones, William York, De' Larrian Knight, Stephen R. Rapp, Aladdin H. Shadyab, JoAnn E. Manson, Ramon Casanova, Robert B. Wallace, Luigi Ferrucci, Susan M. Resnick, Dimitrios Kapogiannis   +17 more
wiley   +1 more source

Non-pharmacological interventions on cognitive functions in mild cognitive impairment and their efficacy in the light of meta-analyses and systematic reviews

Aktualności Neurologiczne, 2019
Recent decades have witnessed a growing interest in the possibilities of non-pharmacological modulation of cognitive functions in older patients using cognitive interventions, such as cognitive training, cognitive stimulation and cognitive rehabilitation.
Ludmiła Zając-Lamparska
doaj   +1 more source

Effect of ApoE E4 Variant on Progression from Mild Cognitive Impairment to Alzheimer’s Disease [PDF]

, 2016
Alzheimer’s disease is a very prevalent and fatal disorder in older adults, and Mild Cognitive Impairment is often seen as a precursor to Alzheimer’s disease.
Taylor, Brad P
core   +1 more source

Risk factors for the progression of mild cognitive impairment to dementia [PDF]

, 2013
The increasing prevalence of cognitive impairment among the older adult population warrants attention to the identification of practices that may minimize the progression of early forms of cognitive impairment, including the transitional stage of mild ...
Boustani, Malaz A., Campbell, Noll L., Khan, Babar A., LaMantia, Michael A., Unverzagt, Fred   +4 more
core   +1 more source

NOTCH2NLC Repeat Expansions in Parkinsonian Disorders: Clinical and Neuroimaging Characteristics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuronal intranuclear inclusion disease (NIID) is a neurodegenerative disorder caused by NOTCH2NLC GGC repeat expansions, with heterogeneous clinical manifestations, including parkinsonism. Recent studies have identified NOTCH2NLC repeat expansions in patients with Parkinson's disease (PD) and atypical parkinsonism (aPM), suggesting ...
Han‐Lin Chiang, Kang‐Yang Jih, Cheng‐Tsung Hsiao, Fu‐Pang Chang, Justus Chunyu Chen, Yi‐Chu Liao, Yih‐Ru Wu, Yi‐Chung Lee   +7 more
wiley   +1 more source

Association of reported sleep disturbances with objectively assessed mild cognitive impairment among adults in the United States

SAGE Open Medicine
Background: Sleep is a multifaceted phenomenon influenced by both duration and quality. Various sleep disturbances have been associated with mild cognitive impairment, but the role of specific disturbances in mild cognitive impairment pathophysiology ...
Chan Shen, Hao Wang, Arthur Nguimatsa Djiotsop, R. Constance Wiener, Mona Pathak, Sophie Mitra, Patricia A Findley, Usha Sambamoorthi   +7 more
doaj   +1 more source