Results 71 to 80 of about 542,808 (329)

Continuous Monitoring of Bladder Dysfunction in People With Multiple Sclerosis: Wearables for the Bladder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Bladder dysfunction affects over 85% of people with multiple sclerosis (PwMS), yet current assessment methods are limited to periodic in‐clinic evaluations or subjective patient reports, failing to capture real‐world symptom fluctuations.
Valerie J. Block, Shane Poole, Leah McIntyre, Nikki Sisodia, Chelyn Park, Gabby Joseph, Michelle E. Van Kuiken, Anne M. Suskind, Riley Bove   +8 more
wiley   +1 more source

White matter abnormalities and structural hippocampal disconnections in amnestic mild cognitive impairment and Alzheimer's disease. [PDF]

PLoS ONE, 2013
The purpose of this project was to evaluate white matter degeneration and its impact on hippocampal structural connectivity in patients with amnestic mild cognitive impairment, non-amnestic mild cognitive impairment and Alzheimer's disease.
Jared Rowley, Vladimir Fonov, Ona Wu, Simon Fristed Eskildsen, Dorothee Schoemaker, Liyong Wu, Sara Mohades, Monica Shin, Viviane Sziklas, Laksanun Cheewakriengkrai, Amir Shmuel, Alain Dagher, Serge Gauthier, Pedro Rosa-Neto, Alzheimer's Disease Neuroimaging Initiative   +14 more
doaj   +1 more source

Molecular Screening of SCN1A‐Related Seizures in Children With Febrile Seizures: Diagnostic Yield and Variant Distribution

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SCN1A‐related seizures first present as febrile seizures (FS). Definitive features emerge later, making early diagnosis challenging. We evaluated the diagnostic yield and clinical characteristics of pathogenic SCN1A variants in FS, and analyzed the effect of variant characteristics on clinical phenotypes required for early ...
Jia Wang, Yang‐Yang Wang, Lin‐Yan Hu, Xiu‐Yu Shi, Wen He, Dan Sun, Baoguang Li, Xiaoming Liu, Sanqing Xu, Lijun Du, Chunhui Tang, Li‐Ping Zou   +11 more
wiley   +1 more source

Mini-Mental State Examination (MMSE) for the detection of Alzheimer's disease and other dementias in people with mild cognitive impairment (MCI).

Cochrane Database of Systematic Reviews, 2015
BACKGROUND Dementia is a progressive global cognitive impairment syndrome. In 2010, more than 35 million people worldwide were estimated to be living with dementia.
I. Arévalo-Rodriguez, N. Smailagic, Marta Roqué i Figuls, A. Ciapponi, E. Sanchez-Perez, Antri Giannakou, O. Pedraza, X. Bonfill Cosp, S. Cullum   +8 more
semanticscholar   +1 more source

Correlation Between Irisin and Cognitive Functions in Alzheimer Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The myokine irisin, a recent positive mediator of exercise in the brain, shows neuroprotective functions against Alzheimer's disease (AD). The association between irisin and cognition has never been explored in a biologically defined cohort of patients.
Patrizia Pignataro, Manuela Dicarlo, Chiara Zecca, Daniele Urso, Maria Teresa Dell'Abate, Davide Vilella, Francesco Borlizzi, Roberta Zerlotin, Angela Oranger, Graziana Colaianni, Silvia Colucci, Maria Grano, Giancarlo Logroscino   +12 more
wiley   +1 more source

The Risk of Incident Mild Cognitive Impairment and Progression to Dementia Considering Mild Cognitive Impairment Subtypes

Dementia and Geriatric Cognitive Disorders Extra, 2017
Background: It remains unclear how demographic and clinical characteristics are related to the risk of incident mild cognitive impairment (MCI) by its subtypes.
Tzeyu L. Michaud, Dejun Su, Mohammad Siahpush, Daniel L. Murman   +3 more
doaj   +1 more source

Dementia and mild cognitive impairment in prisoners aged over 50 years in England and Wales: a mixed-methods study

Health Services and Delivery Research, 2020
Background: People aged ≥ 50 years constitute the fastest-growing group in the prison population of England and Wales. This population has complex health and social care needs.
Katrina Forsyth, Leanne Heathcote, Jane Senior, Baber Malik, Rachel Meacock, Katherine Perryman, Sue Tucker, Rachel Domone, Matthew Carr, Helen Hayes, Roger Webb, Laura Archer-Power, Alice Dawson, Sarah Leonard, David Challis, Stuart Ware, Richard Emsley, Caroline Sanders, Salman Karim, Seena Fazel, Adrian Hayes, Alistair Burns, Mary Piper, Jenny Shaw   +23 more
doaj   +1 more source

Is the Montreal Cognitive Assessment (MoCA) test better suited than the Mini-Mental State Examination (MMSE) in mild cognitive impairment (MCI) detection among people aged over 60? Meta-analysis.

Psychiatria Polska, 2016
OBJECTIVES Screening tests play a crucial role in dementia diagnostics, thus they should be very sensitive for mild cognitive impairment (MCI) assessment.
Natalia Ciesielska, Remigiusz Sokołowski, E. Mazur, Marta Podhorecka, A. Polak-Szabela, K. Kędziora–Kornatowska   +5 more
semanticscholar   +1 more source

Glial Fibrillary Acidic Protein Astrocytopathy Based on a Two‐Center Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glial fibrillary acidic protein astrocytopathy (GFAP‐A) is a recently defined nosological form belonging to the class of autoimmune inflammatory disorders affecting the central nervous system (CNS). Here, we report the clinical and MRI characteristics, treatment, and prognosis of a GFAP‐A cohort from two centers in China.
Ti Wu, Hao Zhang, Chao Gao, Qiuhua Yu, Moli Fan, Lin‐Jie Zhang, Haipeng Zhang, Hengri Cong, Yuzhen Wei, Chotima Böttcher, Alexej Verkhratsky, Friedemann Paul, Fu‐Dong Shi, Tian Song   +13 more
wiley   +1 more source

Prevalence of sarcopenia in multi ethnics adults and the association with cognitive impairment: findings from West-China health and aging trend study

BMC Geriatrics, 2020
Background Sarcopenia is a condition that is characterized by loss of muscle mass, muscle strength and muscle functional impairment with ageing. It is associated with poor health outcomes, premature death and a significant burden on the global health ...
Xiaolei Liu, Lisha Hou, Xin Xia, Yang Liu, Zhiliang Zuo, Yan Zhang, Wanyu Zhao, Qiukui Hao, Jirong Yue, Birong Dong   +9 more
doaj   +1 more source