Results 61 to 70 of about 3,751,517 (253)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Existence of mild solutions of a semilinear evolution differential inclusions with nonlocal conditions

open access: yesElectronic Journal of Differential Equations, 2009
In this paper we prove the existence of a mild solution for a semilinear evolution differential inclusion with nonlocal condition and governed by a family of linear operators, not necessarily bounded or closed, in a Banach space.
Reem A. Al-Omair, Ahmed G. Ibrahim
doaj  

Existence of mild solutions for nonlocal perturbed evolution equations with infinite state-dependent delay in Fréchet spaces [PDF]

open access: yesArchives of Control Sciences
In this work, we give sufficient conditions to get the existence of mild solutions for two classes of first-order semilinear functional and neutral functional perturbed evolution equations with infinite state-dependent delay when the conditions are ...
Selma Baghli-Bendimerad, Imane Abibssi
doaj   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Mild and classical solutions to a fractional singular second order evolution problem

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2012
Existence and uniqueness of mild and classical solutions are discussed for an abstract second-order evolution problem. The nonlinearity contains a local term and a non-local term.
Nasser-Eddine Tatar
doaj   +1 more source

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim   +4 more
wiley   +1 more source

Propagation of Chaos for Weakly Interacting Mild Solutions to Stochastic Partial Differential Equations [PDF]

open access: yes, 2022
This article investigates the propagation of chaos property for weakly interacting mild solutions to semilinear stochastic partial differential equations whose coefficients might not satisfy Lipschitz conditions.
Criens, David
core   +1 more source

Spatial asymptotics of mild solutions to the time-dependent Oseen system

open access: yes, 2022
We consider mild solutions to the 3D time-dependent Oseen system with homogeneous Dirichlet boundary conditions, under weak assumptions on the data. Such solutions are defined via the semigroup generated by the Oseen operator in L^q.
Deuring, Paul
core  

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Strong, Mild and Weak Solutions

open access: yes, 2007
Prévôt C, Röckner M. Strong, Mild and Weak Solutions. In: Prévôt C, Röckner M, eds. A Concise Course on Stochastic Partial Differential Equations. Lecture Notes in Mathematics. Vol 1905.
Prévôt, Claudia, Röckner, Michael
core  

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