Results 61 to 70 of about 3,751,517 (253)
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
In this paper we prove the existence of a mild solution for a semilinear evolution differential inclusion with nonlocal condition and governed by a family of linear operators, not necessarily bounded or closed, in a Banach space.
Reem A. Al-Omair, Ahmed G. Ibrahim
doaj
Existence of mild solutions for nonlocal perturbed evolution equations with infinite state-dependent delay in Fréchet spaces [PDF]
In this work, we give sufficient conditions to get the existence of mild solutions for two classes of first-order semilinear functional and neutral functional perturbed evolution equations with infinite state-dependent delay when the conditions are ...
Selma Baghli-Bendimerad, Imane Abibssi
doaj +1 more source
Comparing the paths of Hedgehog release in artificial and natural settings
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
Mild and classical solutions to a fractional singular second order evolution problem
Existence and uniqueness of mild and classical solutions are discussed for an abstract second-order evolution problem. The nonlinearity contains a local term and a non-local term.
Nasser-Eddine Tatar
doaj +1 more source
Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim +4 more
wiley +1 more source
Propagation of Chaos for Weakly Interacting Mild Solutions to Stochastic Partial Differential Equations [PDF]
This article investigates the propagation of chaos property for weakly interacting mild solutions to semilinear stochastic partial differential equations whose coefficients might not satisfy Lipschitz conditions.
Criens, David
core +1 more source
Spatial asymptotics of mild solutions to the time-dependent Oseen system
We consider mild solutions to the 3D time-dependent Oseen system with homogeneous Dirichlet boundary conditions, under weak assumptions on the data. Such solutions are defined via the semigroup generated by the Oseen operator in L^q.
Deuring, Paul
core
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Strong, Mild and Weak Solutions
Prévôt C, Röckner M. Strong, Mild and Weak Solutions. In: Prévôt C, Röckner M, eds. A Concise Course on Stochastic Partial Differential Equations. Lecture Notes in Mathematics. Vol 1905.
Prévôt, Claudia, Röckner, Michael
core

