Comparative effectiveness of myocardial cytoprotectors in chronic heart failure treatment
The study is focused on comparative effectiveness of myocardial cytoprotectors in chronic heart failure (CHF) treatment. In total, 120 patients with Functional Class (FC) II-III CHF were divided into two groups.
G. G. Semenkova, L. V. Kokoreva
doaj
Importance of the Pharmacological Synergismin Modern Concept of Anti-Ischemic Therapy [PDF]
Nowadays, the increase of therapy efficacy of ischemic conditions in cardiology and neurology is one of the top trends in clinical, pharmaceutical and pharmacological studies on a global scale.
I A Zupanets
core
New views of mildronate use for the prevention and correction of impairment of adaptive processes
Protective and normalizing mildronate action on the level of non enzyme kation proteins in the neurophils and contents of kateholamins in erythrocytes were revealed on the experimental model of the emotional-pain stress.
L V Logunova
doaj
COMPUTATIONAL ANALYSIS OF INTERACTIONS BETWEEN ANTI-EPILEPTIC DRUGS AND IMPORTANT PLACENTAL PROTEINS-A POSSIBLE ROUTE FOR NEURAL TUBE DEFECTS IN HUMANS [PDF]
Objective: The reason behind the occurrence of Neural Tube Defects (NTDs) in pregnant women treated with certain Anti-Epileptic Drugs (AEDs) such as Carbamazepine, Valproate, Lamotrigine, Phenobarbital, etc., is not yet known.
Agrawal, Arvind +3 more
core +1 more source
Mildronate (meldonium): First, do no harm
Meldonium (Mildronate) is used as a cardioprotective drug; however, it has not been officially approved anywhere outside the former Soviet Union (SU). The supposed action mechanism is based on the carnitine (Lcarnitine) lowering effect in muscular and cardiac tissues.
openaire +1 more source
Study of the cardioprotective metabolic effects of mildronate [PDF]
Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, Disciplina de medicină internă-semiologie, Chișinău, Republica Moldova, Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină și Farmacie „Nicolae ...
Chetruș, Olga
core
MAIN THERAPEUTIC PRINCIPLES IN PREMENOPAUSAL WOMEN
The review outlines the main mechanisms of protective estrogen effects on cardiovascular system and the role of estrogen deficiency in cardiovascular disease (CVD) development. The position of the International Menopause Society (2009) on CVD in women is
S. N. Tolstov +5 more
doaj
Introduction: Currently, chronic heart failure (CHF) is one of the leading problems of modern healthcare. Its most common manifestation is the deterioration of the inotropic reserves of the heart muscle, which over time leads to decompensation and damage
Valentin Kataev +8 more
doaj +1 more source
In total, 149 patients, aged 41–75 years, with Functional Class (FC) II-III stable angina, who underwent coronary artery bypass graft surgery (CABG) or percutaneous coronary intervention (PCI), were examined.
I. G. Gordeev +2 more
doaj
Inhibition of mitochondrial fatty acid β-oxidation activates mTORC1 pathway and protein synthesis via Gcn5-dependent acetylation of Raptor in zebrafish. [PDF]
Zhou WH +8 more
europepmc +1 more source

