Meldonium – A High Potential Drug. Literature Review [PDF]
Introduction and purpose: Meldonium is a long-established substance. Initially, the substance was only available in the former Soviet Union; now the drug can be obtained, for example, in Poland.
Dąbek, Katarzyna +7 more
core +1 more source
The paper presents the results of 3 prospective, randomised, double-blind, placebo-controlled trials of patients with coronary heart disease (CHD) and peripheral artery disease (PAD).
V. Ya. Dzerve, Yu. M. Pozdnyakov
doaj
Obese Ningxiang pig-derived microbiota rewires carnitine metabolism to promote muscle fatty acid deposition in lean DLY pigs. [PDF]
Yin J +11 more
europepmc +1 more source
In total, 60 45-70-year-old patients with Functional Class II-III chronic heart failure (CHF) after a myocardial infarction, compensated or sub-compensated Type 2 diabetes mellitus (DM-2), and autonomous cardiac neuropathy were examined.
M. E. Statsenko +2 more
doaj
Mildronate improves carotid baroreceptor reflex function in patients with chronic heart failure [PDF]
Summary Objectives: The aim of the study was to compare the efficacy of combined treatment of chronic heart failure (CHF) patients with mildronate and ACEI (lisinopril) and the treatment with ACEI (lisinopril) used alone.
Andris Vitols +2 more
core
Development and validation of an UHPLC-Orbitrap-HRMS method for rapid determination of endogenous L-carnitine in patients on hemodialysis/peritoneal dialysis and its application to promote rational drug use. [PDF]
Jiang WT +7 more
europepmc +1 more source
Aim. To study fractional composition of red cell membrane (RCM) lipids in patients with severe iron-deficiency anemia (IDA) complicated by myocardiodystrophy prior to treatment and after 1-month combined treatment with sorbifer and mildronate.
E V Goncharova, A V Govorin
doaj
Meldonium Inhibits Cell Motility and Wound-Healing in Trabecular Meshwork Cells and Scleral Fibroblasts: Possible Applications in Glaucoma. [PDF]
Minnelli C +9 more
europepmc +1 more source
Changes in L-Carnitine Metabolism Affect the Gut Microbiome and Influence Sexual Behavior Through the Gut-Testis Axis. [PDF]
Babenkova P +9 more
europepmc +1 more source
L-Carnitine and Mildronate Demonstrate Divergent Protective Effects on Mitochondrial DNA Quality Control and Inflammation Following Traumatic Brain Injury. [PDF]
Gureev AP +5 more
europepmc +1 more source

