Results 131 to 140 of about 624 (180)

Mildronate: An Antiischemic Drug for Neurological Indications [PDF]

open access: yesCNS Neuroscience & Therapeutics, 2005
ABSTRACTMildronate (3‐(2,2,2‐trimethylhydrazinium)propionate; MET‐88; meldonium, quaterine) is an antiischemic drug developed at the Latvian Institute of Organic Synthesis. Mildronate was designed to inhibit carnitine biosynthesis in order to prevent accumulation of cytotoxic intermediate products of fatty acid β‐oxidation in ischemic tissues and to ...
Aleksandrs Gutcaits   +2 more
exaly   +3 more sources

Protective effects of mildronate in an experimental model of type 2 diabetes in Goto-Kakizaki rats [PDF]

open access: yesBritish Journal of Pharmacology, 2009
Background and purpose: Mildronate [3-(2,2,2-trimethylhydrazinium) propionate] is an anti-ischaemic drug whose mechanism of action is based on its inhibition of L-carnitine biosynthesis and uptake.
Baiba Svalbe   +2 more
exaly   +2 more sources

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