Results 141 to 150 of about 354 (165)

[Efficacy and safety of mildronate in emergency medical care].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2014
Detailed clinical data about patients who used emergency services during 2011 are presented. The main attention is focused on the state of patients with acute and chronic brain ischemia before and after treatment with mildronate. Mean age of patients with ischemic stroke and chronic brain ischemia was 63.4 and 57.7 years, respectively.
N M, Nevzorov, Yu N, Markevich
openaire   +1 more source

MILDRONATE

Drugs of the Future, 1989
J. Prous, J. Castañer
openaire   +1 more source

[Evaluation of effectiveness of treatment of cochleovestibular disorders with mildronate].

Vestnik otorinolaringologii, 1991
The results of mildronate treatment of 67 patients with acute (23 patients) and chronic (44 patients) cochleovestibular disorders of different origin are discussed. The efficacy was evaluated in terms of subjective reports and objective parameters. The therapy proved effective in 53 (79.1%) patients, out of which it was good in 30 (44.8%) patients and ...
L A, Luchikhin, T B, Pankova, M I, Kakymov   +2 more
openaire   +1 more source

Meldonium (Mildronate): A Performance‐Enhancing Drug?

Clinical Pharmacology in Drug Development, 2016
H Karl, Greenblatt, David J, Greenblatt
openaire   +2 more sources

The in vivo disposition of mildronate and its regulatory effects on L-carnitine in rats

Naunyn-Schmiedeberg's Archives of Pharmacology
To develop an LC-MS/MS method for simultaneous quantification of mildronate and L-carnitine, and to investigate the pharmacokinetic profile of mildronate in rats, its effect on L-carnitine homeostasis, as well as the exposure characteristics, underlying mechanisms, and their associations with therapeutic efficacy and toxicity risks.
Qiannan, Zhang, Junwen, Hu, Chuyao, Yang, Jingtao, Wang, Xia, Wu, Lingchao, Wang, Wenpeng, Zhang, Xiaomei, Zhuang   +7 more
openaire   +2 more sources

Structures of Mildronate Polymorphic and Pseudopolymorphic Forms

Latvian Journal of Chemistry, 2011
A. Zvirgzdiņš, K. Veldre, A. Actiņš
openaire   +1 more source

[The effect of mildronate on carnitine-dependent and carnitine-independent ketogenesis in rats].

Farmakologiia i toksikologiia, 1992
Mildronate of 3-(2,2,2-trimethylhydrozinium)propionate, a novel anti-ischemic drug, inhibits the biosynthesis of carnitine from Y-butyrobetaine. Continuous administration of mildronate (200, 400 mg/kg for 10 days orally) to rats exerted a marked antiketogenic action on the animals deprived of food for 48 hours.
B Z, Simkhovich, D V, Meĭrena, Kh B, Khagi, Zh V, Shutenko, T N, Molodchina, I Ia, Kalvin'sh, E Ia, Lukevits   +6 more
openaire   +1 more source

[The efficacy of the mildronate treatment of patients with ischemic stroke].

Vrachebnoe delo, 1992
A study is presented of the clinico-hemodynamic efficacy of mildronate in 38 patients with ischemic stroke. The drug produces a positive inotropic effect on the myocardium, improves the cerebral hemodynamics in patients with stroke and postischemic hypo- and hyperperfusion of the brain tissue.
openaire   +1 more source

The Cardioprotective Effect of Mildronate is Diminished After Co-Treatment With l -Carnitine

Journal of Cardiovascular Pharmacology and Therapeutics, 2012
Osvalds Pugovics, Reinis Vilskersts, Jänis Kuka   +2 more
exaly  

Anti-diabetic effects of mildronate alone or in combination with metformin in obese Zucker rats

European Journal of Pharmacology, 2011
Baiba Svalbe, Maija Dambrova, Edgars Liepinš   +2 more
exaly