Оn-pump coronary bypass surgery was performed in 58 stable angina patients aged 43-72. Group I (n = 19) received standard coronary heart disease (CHD) treatment, together with mildronate: before the surgery, 750 mg/d for 3 days, then 750 mg/d twice a ...
I. G. Gordeev +5 more
doaj
Structure of mildronate, its pharmaceutical salts and cocrystals [PDF]
A. Mishnev +3 more
openaire +1 more source
Synthesis and in silico research of derivatives of 3-allyl-4-(R-phenyl)-N-(R1-phenyl)thiazole-2-imine [PDF]
The synthesis of those new derivatives of 3-allyl-4-(R-phenyl)-N-(R1-phenyl)-thiazole-2-imine was conducted which consist substituted aromatic radicals. Structure of the compounds synthesized has proved by means of a comprehensive use of modern physical ...
Drapak, I. V. +12 more
core
The paper presents the results of 3 prospective, randomised, double-blind, placebo-controlled trials of patients with coronary heart disease (CHD) and peripheral artery disease (PAD).
V. Ya. Dzerve, Yu. M. Pozdnyakov
doaj
In total, 60 45-70-year-old patients with Functional Class II-III chronic heart failure (CHF) after a myocardial infarction, compensated or sub-compensated Type 2 diabetes mellitus (DM-2), and autonomous cardiac neuropathy were examined.
M. E. Statsenko +2 more
doaj
Obese Ningxiang pig-derived microbiota rewires carnitine metabolism to promote muscle fatty acid deposition in lean DLY pigs. [PDF]
Yin J +11 more
europepmc +1 more source
Aim. To study fractional composition of red cell membrane (RCM) lipids in patients with severe iron-deficiency anemia (IDA) complicated by myocardiodystrophy prior to treatment and after 1-month combined treatment with sorbifer and mildronate.
E V Goncharova, A V Govorin
doaj
Meldonium Inhibits Cell Motility and Wound-Healing in Trabecular Meshwork Cells and Scleral Fibroblasts: Possible Applications in Glaucoma. [PDF]
Minnelli C +9 more
europepmc +1 more source
Development and validation of an UHPLC-Orbitrap-HRMS method for rapid determination of endogenous L-carnitine in patients on hemodialysis/peritoneal dialysis and its application to promote rational drug use. [PDF]
Jiang WT +7 more
europepmc +1 more source
Changes in L-Carnitine Metabolism Affect the Gut Microbiome and Influence Sexual Behavior Through the Gut-Testis Axis. [PDF]
Babenkova P +9 more
europepmc +1 more source

