Results 91 to 100 of about 1,251,485 (312)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

Development of Fermented Mare’s Milk Using Mixed Probiotic Cultures

open access: yesMedia Peternakan, 2016
Mare’s milk has good nutrient composition for human being in the form of natural milk or milk products. It can be used to replace cow’s milk, especially in the regions outside of Java Island which are rarely found dairy cow.
T. W. Murti   +5 more
doaj   +1 more source

Milk somatic cells, factors influencing their release, future prospects, and practical utility in dairy animals: An overview

open access: yesVeterinary World, 2018
Milk somatic cells (SCs) are a mixture of milk-producing cells and immune cells. These cells are secreted in milk during the normal course of milking and are used as an index for estimating mammary health and milk quality of dairy animals worldwide. Milk
Mohanned Naif Alhussien, A. Dang
semanticscholar   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Human breast milk: A review on its composition and bioactivity.

open access: yesEarly Human Development, 2015
Breast milk is the perfect nutrition for infants, a result of millions of years of evolution, finely attuning it to the requirements of the infant. Breast milk contains many complex proteins, lipids and carbohydrates, the concentrations of which alter ...
Nicholas J. Andreas   +2 more
semanticscholar   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

open access: yesAdvanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio   +11 more
wiley   +1 more source

Synbiotic combination of Bifidobacterium longum BB536 and lactulose improves the presenteeism of healthy adults associated with aromatic lactic acids - A single-arm, open-label study

open access: yesGut Microbes Reports
Gut microbiota and their metabolites are crucial for metabolic regulation, immunomodulation, and brain and mental functions via the brain-gut axis. Synbiotics offer an effective strategy for improving gut health by modulating gut microbiota, leading to ...
Riko Mishima   +14 more
doaj   +1 more source

Human Milk Oligosaccharides: 2′-Fucosyllactose (2′-FL) and Lacto-N-Neotetraose (LNnT) in Infant Formula

open access: yesNutrients, 2018
The authors reviewed the published evidence on the presence of oligosaccharides in human milk (HMO) and their benefits in in vitro and in vivo studies.
Y. Vandenplas   +11 more
semanticscholar   +1 more source

Engineered Mycelial Scaffolds With Tunable Ultraviolet Protection, Wettability, Thermal Stability, and Spatial Mechanics

open access: yesAdvanced Engineering Materials, EarlyView.
Fungal mycelia grown into biodegradable scaffolds and infused with titania nanoparticles show enhanced ultraviolet shielding, thermal protection, and surface nonwettability. Properties were tuned by drying methods, revealing structure–function relationships.
Juwon S. Afolayan   +2 more
wiley   +1 more source

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