Results 231 to 240 of about 1,251,485 (312)

Response of mid-lactation primiparous Holstein cows to the supplementation of rumen-protected methionine during the summer. [PDF]

PLoS One
Monteiro CR, de Oliveira VA, Schmith R, Rezende JPA, Resende TL, Negrão JA, Danés MAC.   +6 more
europepmc   +1 more source

Amodiaquine Enhances Anti‐Melanoma Efficacy of Attenuated Salmonella via Targeting Glutathione Reductase in Neutrophils

Advanced Science, EarlyView.
This study shows that Salmonella VNP20009 recruits pro‐tumor neutrophils that reduce its anticancer efficacy. Combining VNP with amodiaquine selectively eliminates these neutrophils by targeting glutathione reductase. A GR‐shRNA‐loaded VNP strain was further developed, demonstrating an innovative strategy integrating drug repurposing with synthetic ...
Wanfa Dong, Chunyuan Zhao, Chengxi Li, Lin Weng, Zehan Ji, Peiqi Li, Jiqiang Lu, Danni Liu, Anni Yu, Tianyi Jiang, Shaokai Huang, Heng Liu, Xiao Chen, Zichun Hua   +13 more
wiley   +1 more source

Dietary supplementation with microbially fermented rice bran promotes lactation performance in dairy cows by increasing rumen fermentation performance and nutrient digestibility. [PDF]

Front Vet Sci
Zhang Z, Cai W, Wei X, He B, Liu Y, Zhang X, Yang J, Li F, Li Z, Wang C.   +9 more
europepmc   +1 more source

Discovery of SKP2‐Recruiting PROTACs for Target Protein Degradation

Advanced Science, EarlyView.
Based on the SKP2‐targeting ligand SL1, we designed non‐covalent PROTACs by linking it with the BRD4 inhibitor JQ1 and the AR antagonist AL through a linker. These PROTACs successfully induced the ubiquitination of BRD4 and AR, followed by proteasome‐mediated degradation.
Guanjun Dong, Aima Huang, Ziqing Zhao, Bikai Lai, Xin Pan, Huiyu Yang, Xiaohan Xu, Tianwei Wang, Fangchen Zhao, Zhimin Zhang, Yongbo Xue, Guanjun Deng, Wenbin Deng, Jianwei Chen   +13 more
wiley   +1 more source

A pilot study of maternal vitamin D status and its association with breast milk and infant gut metabolites. [PDF]

Physiol Rep
Gutierrez AS, Chetta KE, Thapa S, Haidacher SJ, Hoch KM, Baatz JE, Haag AM, Oezguen N, Horvath TD, Wagner CL, Engevik MA.   +10 more
europepmc   +1 more source

A Prospective and Cost-Effective Voltammetric-Chemometric Approach for the Discrimination and Quantification of Melamine and Urea in Milk. [PDF]

ACS Omega
Putra BR, Nikma SH, Rafi M, Wahyuni WT.
europepmc   +1 more source

Climate-Driven Aflatoxin M₁ Risks in Serbia: Implications for Integrated Food Safety Management Along the Dairy Chain. [PDF]

Toxins (Basel)
Milićević DR, Udovički B, Šuša A, Rajković A, Pleadin J.   +4 more
europepmc   +1 more source