Results 241 to 250 of about 1,701,267 (359)

Maternal diet and fatty acids in human milk: results of the MELK study. [PDF]

Eur J Nutr
Petersohn I, Zock PL, Knipping K, Brouwer-Brolsma EM, Feskens EJM.   +4 more
europepmc   +1 more source

Porcine Deltacoronavirus M Protein Binds NLRP3 to Promote Inflammasome Assembly via Competition with TRIM31

Advanced Science, EarlyView.
Porcine deltacoronavirus (PDCoV) infection induces severe intestinal inflammation and acute diarrhea in piglets, yet the molecular mechanism remains incompletely understood. The M protein activates NLRP3 inflammasome through dual mechanisms: direct binding to the NLRP3 LRR domain and disruption of TRIM31‐mediated K48‐linked ubiquitination.
Jinhui Hou, Fangfang Han, Anqi Liu, Yang Yu, Rui Zhao, Zhengting Shi, Yanrong Lv, Jinli Liu, Shaopo Zu, Zhanyong Wei, Jin Yuan, Hui Hu   +11 more
wiley   +1 more source

Milk-Sickness [PDF]

Science, 1886
openaire   +3 more sources

Cerium Nanoparticle‐Mediated Inhibition of the NSUN2/m5C Axis Suppresses Synovial Aggression in Rheumatoid Arthritis

Advanced Science, EarlyView.
A novel epitranscriptomic mechanism in rheumatoid arthritis is uncovered: NSUN2 promotes disease via m5C‐dependent stabilization of ICMT mRNA, fueling the migration and invasion of pathogenic RA FLS. Targeting this axis with engineered nanoparticles (Ce/SAA NPs) effectively inhibits disease progression, presenting a precise therapeutic strategy ...
Ruiru Li, Simin Chen, Huijuan Hu, Shiyao Wu, Jingnan Wang, Kai Sun, Chenxi Peng, Suling Liu, Shuoyang Zhang, Yu Kuang, Wei Chen, Qian Qiu, Liuqin Liang, Yu Wen, Hanshi Xu, Youjun Xiao   +15 more
wiley   +1 more source

Mineral Profiling of Preterm, Term Breast Milk, and Commercial Infant Formula: Evaluating Nutritional Adequacy for Premature Neonates. [PDF]

Prev Nutr Food Sci
Latif S, Shafique MA, Khalid N.
europepmc   +1 more source

Sheep Milk: Physicochemical Characteristics and Relevance for Functional Food Development.

Comprehensive Reviews in Food Science and Food Safety, 2017
C. Balthazar, T. C. Pimentel, L. L. Ferrão, C. N. Almada, A. Santillo, M. Albenzio, N. Mollakhalili, A. Mortazavian, J. S. Nascimento, M. C. Silva, M. Q. Freitas, A. S. Sant'Ana, D. Granato, A. Cruz   +13 more
semanticscholar   +1 more source

Liver Endothelia Orchestrate MASH‐Associated Macrophage Zonation Through FSTL1‐ITGA4 Axis

Advanced Science, EarlyView.
Liver inflammation in MASH fundamentally hinges on the newly defined Kit/STAT2/FSTL1/ITGA4 axis. Declining endothelial Kit collapses normal hepatic zonation, driving an aberrant FSTL1 gradient that recruits pathogenic macrophages. Strikingly, targeting FSTL1‐ITGA4 with anti‐VLA4 restores spatial immune homeostasis and halts disease progression ...
Lin Sun, Zhensheng Yue, Zhiqiang Fang, Hao Xu, Wei Du, Yuwei Ling, Jingjing Liu, Ping Song, Fei He, Juanli Duan, Lin Wang   +10 more
wiley   +1 more source

Lipidomic Profiling of Milk Enables Identification of Novel Biomarkers for Subclinical Ketosis in Dairy Cows. [PDF]

Foods
Liu Z, Ezernieks V, Hemsworth JE, Reich CM, Bath CR, Berkhout MJ, Tahir MS, Marett LC, Chamberlain AJ, Goddard ME, Xiang R, Rochfort SJ.   +11 more
europepmc   +1 more source

LRRC4 Orchestrates AP2A1‐Containing Clathrin‐Coated Vesicles to Disrupt Mitochondrial Cristae and Restrict Glioblastoma Progression

Advanced Science, EarlyView.
LRRC4 suppresses GBM by regulating AP2A1‐containing Golgi‐derived clathrin‐coated vesicles. Low LRRC4 allows cytoplasmic AP2A1 to maintain mitochondrial fission‐fusion, MICOS integrity, and OXPHOS, promoting proliferation and invasion. High LRRC4 redirects AP2A1‐containing Golgi‐derived clathrin‐coated vesicles to mitochondria, disrupts MICOS, enhances
Yang Li, Cheng Huang, Liangqi Jiang, Zhen Li, Qing Liu, Minghua Wu   +5 more
wiley   +1 more source

Characterizing the Milk Microbiome in Subclinical Mastitis: A Pilot 16S rRNA-Based Study in Cattle and Water Buffalo. [PDF]

Vet Med Sci
Masum MHU, Nayem MR, Mahdeen AA, Sultana S, Barua A.   +4 more
europepmc   +1 more source