Results 231 to 240 of about 1,701,267 (359)

Adiposity-dependent adipokine-immunoglobulin interplay in mature breast milk. [PDF]

Front Endocrinol (Lausanne)
Lis-Kuberka J, Humaj-Grysztar M, Apanasewicz A, Matyas M, Ziomkiewicz A, Orczyk-Pawiłowicz M.   +5 more
europepmc   +1 more source

Nanozyme‐Reinforced miR‐197‐3p Delivery Resets Metabolic and Senescence Pathways to Rejuvenate Osteoarthritic Cartilage

Advanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a progressive and disabling joint disease driven by oxidative stress, chondrocyte senescence and extracellular matrix (ECM) degradation, yet lacks effective disease‐modifying treatments. In this study, we identified miR‐197‐3p as a previously unrecognized, cartilage‐protective miRNA significantly downregulated in both ...
Xuejie Cai, Zehui Lv, Chen Zhang, Xingdong Yang, Ruoying Wang, Yixin Bian, Jiawei Xu, Han Wang, Yingjie Wang, Long Bai, Jiacan Su, Xisheng Weng   +11 more
wiley   +1 more source

The Effect of Resistance Training on Physical Function Is Associated With Changes in Serum Albumin Redox States in Middle-Aged and Older Japanese Adults

Current Developments in Nutrition
Takuya Shibasaki, Hirohiko Nakamura, Yuka Kurosaka, Shuji Sawada, Kazuhiro Miyaji, Shuichi Machida   +5 more
doaj   +1 more source

Effects of preterm birth and gestational diabetes on innate lymphoid cells (ILCs) in human breast milk. [PDF]

Mol Cell Pediatr
Raché M, Lükewille L, Vogelgesang A, Lange A, Ittermann T, Heckmann M, Ruhnau J.   +6 more
europepmc   +1 more source

Overview of Nutrients in Human Milk.

Advances in Nutrition, 2018
D. Dror, L. Allen
semanticscholar   +1 more source

Targeting NSUN2‐Mediated m5C Modification Attenuates Chondrocyte Senescence and NLRP3 Activation in Osteoarthritis

Advanced Science, EarlyView.
NSUN2‐mediated m5C modification cooperates with ALYREF to stabilize and export IP3R3 mRNA, increasing IP3R3 expression and Ca2 + overload in chondrocytes. This signaling promotes mitochondrial dysfunction, NLRP3 inflammasome activation, and senescence, thereby accelerating osteoarthritis progression.
Guping Mao, Wei Li, Zhencan Lin, Zengfa Deng, Ming Li, Zongrui Jiang, Changzhao Li, Dianbo Long, Yan Kang   +8 more
wiley   +1 more source

ncRNAs in breast milk of mothers with SLE: potential implications for neonatal immune development. [PDF]

Front Immunol
Chwatko JW, Rakhmetullina A, Zielenkiewicz P, Pączek L.   +3 more
europepmc   +1 more source

EpCAM+ Extracellular Vesicle PD‐L1 Dynamics as a Predictive Biomarker of Immune Checkpoint Blockade Response

Advanced Science, EarlyView.
A highly sensitive SERS‐based platform measures PD‐L1 expression on EpCAM+ circulating EVs from cancer patients undergoing immunotherapy. Monitoring dynamic changes after treatment reveals that reduced EpCAM+ EV PD‐L1 levels associate with improved long‐term clinical outcomes, establishing a non‐invasive approach for tracking immune checkpoint ...
Byeonggeol Mun, Jinyoung Kim, Chang Gon Kim, Seokhyeong Go, Mina Han, Yujin Ouck, Soojin Jang, Seong Uk Son, Gamin Kim, Wonrak Son, Eunjung Kim, Min Hee Hong, Ja Hyun Yeo, Eun‐Kyung Lim, Hye Ryun Kim, Seungjoo Haam   +15 more
wiley   +1 more source

Survey of Smallholder Dairy Cattle Farming System and Antibiotic Residues in Raw Cow's Milk in Bagamoyo District, Tanzania. [PDF]

Vet Med Sci
Ramadhani RI, Nonga HE.
europepmc   +1 more source

Pathological Copper Overload Reprograms SOD1 Activation via COMMD1 to Promote Senescence and Fibrosis

Advanced Science, EarlyView.
This study uncovers a previously unrecognized copper‐COMMD1‐SOD1 regulatory axis, revealing that pathological copper overload paradoxically suppresses SOD1 activity by promoting COMMD1‐dependent disruption of SOD1 homodimerization. These findings redefine the regulatory role of copper in SOD1 biology and provide novel mechanistic insight into the ...
Yuqing Liu, Jing Liu, Wenqian Zhou, Yangyang Niu, Yan Zheng, Yiguo Liu, Yingying Zhang, Chen Yu   +7 more
wiley   +1 more source