Results 101 to 110 of about 611,678 (362)

RIG‐I Mediated Neuron‐Specific IFN Type 1 Signaling in FUS‐ALS Induces Neurodegeneration and Offers New Biomarker‐Driven Individualized Treatment Options for (FUS‐)ALS

Advanced Science, EarlyView.
Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann, Theresa M. Wierschin, Stefanie Kretschmer, Banaja P. Dash, Aaron Held, Andrea Salzinger, Kevin Peikert, Anže Karlek, Hannes Glaß, Dajana Großmann, René Günther, Susanne Petri, Annekathrin Rödiger, David Brenner, Francisco Pan‐Montojo, Eleonora Aronica, Markus Kipp, Vitaly Zimyanin, Jared Sterneckert, Torsten Grehl, Noah D. Seebacher, Tobias M. Böckers, Alberto Catanese, Brian J. Wainger, Patrick Oeckl, Min Ae Lee‐Kirsch, Andreas Hermann   +26 more
wiley   +1 more source

A New Direction for the Payment of Milk: Technological and Seasonality Considerations in Multiple Component Milk Pricing of Milk (Liquid and Manufacturing) for a Diversifying Dairy Industry [PDF]

, 2007
End of project reportThe main objectives of this study were to compare a Multiple Component Pricing system with the current milk pricing practice in Ireland and to estimate the marginal values of the three main milk components (fat, protein and lactose ...
Breen, J., Crosse, Seamus, O'Callaghan, Donal, Wallace, Michael   +3 more
core  

Skinny on Low-fat and Fat-free Milk and Milk Products

EDIS, 2011
Whether you are young or old, consuming fat-free and low-fat milk products every day is important for good health. This 5-page fact sheet highlights the purpose of including foods from the Milk group in the diet and the daily amounts needed for children and adults. It also includes helpful hints for those who are lactose intolerant.
Lauren Headrick, Karla P. Shelnutt
openaire   +1 more source

NNMT Orchestrates Metabolic‐Epigenetic Reprogramming to Drive Macrophage‐Myofibroblast Transition in Hypertrophic Scarring

Advanced Science, EarlyView.
In macrophage‐myofibroblast transition, upregulated NNMT depletes S‐Adenosylmethionine‌ (SAM) and nicotinamide adenine dinucleotide(NAD+), thereby triggering epigenetic reprogramming via Histone H3 Lysine 27 acetylation (H3K27ac) accumulation at the promoter region of master transcription factor Prrx1.
Xiwen Dong, Weinan Guo, Yuxuan Qian, Wenyan Jin, Xiaozhen Li, Jingyuan Yang, Qingrong Ni, Shuang Wu, Fanni Li, Hua Wang, Chunying Li, Hong Cai   +11 more
wiley   +1 more source

PENGARUH PERBANDINGAN PEMANIS (SUKROSA, FRUKTOSA DANGLUKOSA) TERHADAP KUALITAS PERMEN SUSU KAMBING PERANAKAN ETAWA (PE) SECARA FERMENTASI [PDF]

, 2009
Milk is the valuable and perfect food-stuff of high nutrition, because containing most of food subtance like carbohydrate, protein, fat, vitamin and mineral.
Pramesti Wijaya, Vera
core  

Bisphenol B Exposure Induces Miscarriage by Suppressing Migration/Invasion and Migrasome Formation

Advanced Science, EarlyView.
BPB (Bisphenol B) exposure up‐regulates ER (estrogen receptor) levels, enhances its interactions with the lnc‐HZ04 promoter region, and thus promotes ER‐mediated lnc‐HZ04 transcription. Subsequently, lnc‐HZ04 suppresses TCF4 (transcription factor 4)‐mediated PKCA (protein kinase C alpha) transcription and subsequently suppresses migration/invasion and ...
Wenxin Huang, Manli Wang, Yi Sun, Xiaoping Yue, Xun Li, Yanbing Lin, Geng Guo, Depeng Zhao, Qigang Fan, Xiaoling Ma, Zhihong Zhang, Shuaishuai Xing, Xiaoting Shen, Huidong Zhang   +13 more
wiley   +1 more source

Effects of dietary sources of vegetable fats on performance of dairy ewes and conjugated linoleic acid (CLA) in milk. [PDF]

, 2009
Two experiments were carried out to study the effects of supplementing the ration of lactating ewes with vegetable fats (sunflower oil, SO or hydrogenated palm oil, HPO; HIDROPALM (R)) on diet digestibility, milk yield and milk composition, and on the ...
A.R. Mantecón, Allred, AOAC, Appeddu, Bell, Bernard, Bocquier, Bouattour, Bouattour, Bu, Casals, Casals, Chilliard, Chiofalo, Corl, Doreau, Eastridge, Gargouri, Griinari, Griinari, Grummer, Harvatine, Hogan, Huang, Ip, Kalscheur, Kitessa, Lock, Lock, M. Del Alamo, Mir, Ntambi, Ohajuruka, Palmquist, Palmquist, Park, Perfield, Peterson, Pérez Alba, Reddy, Salado, Sanz Sampelayo, Schmidely, Soyeurt, T. Castro, T. Manso, Ulbright, V. Jimeno, Van Soest, Wachira, Wolff, Wu, Zervas, Zhang, Zheng   +54 more
core   +2 more sources

Effect of a blend of palmitic and stearic acid on transfer of preformed fatty acids into milk fat using an 18 C n-3 fatty acid perturbation model

Journal of Dairy Science
: The transfer of dietary fatty acids (FA) into milk fat is variable and has been reported to be higher on lower fat diets, which may be a homeorhetic adaptation to support milk fat production.
Y.A. Adeniji, S.L. Burtnett, M.I. Ibrahim, K.J. Harvatine   +3 more
doaj   +1 more source

Perfluorooctanoic Acid Exposure Causes Macrophage Ammonia Retention and Induces Spontaneous Miscarriages

Advanced Science, EarlyView.
PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao, Yijun Zhang, Hanyu Rao, Jiani Sun, Zhiyi Pan, Liping Jin, Yan Zhao   +6 more
wiley   +1 more source

PERSPECTIVE OF USE OF MILK SUBSTITUTOR ON DAIRY PRODUCTION

Алматы технологиялық университетінің хабаршысы, 2021
The article provides information on the use of milk fat substitutes in dairy production and its future prospects. Presents physico-chemical characteristics of fat substitutes "Ecolect" company "EFKO".

doaj