Results 251 to 260 of about 611,678 (362)

Milk fat globule stability

open access: yes, 2005
The implementation of automatic milking systems (AMS) initially caused a lowering of the milk quality regarding free fatty acids (FFA). A high level of FFA increases the risk of rancid flavour in dairy products. The objective of the present thesis was to evaluate different factors in AMS which could potentially cause an increased level of FFA.
openaire   +1 more source

Conversion of Transplanted Mature Hepatocytes into Afp+ Reprogrammed Cells for Liver Regeneration After Injury

open access: yesAdvanced Science, EarlyView.
Donor‐derived tdTomato+ mature hepatocytes were FACS‐isolated and transplanted into Fah−/− host mice. During regeneration, these cells convert into proliferative, unipotent Afp+ rHeps. Their plasticity is governed by a PPARγ/AFP‐dependent metabolic switch, segregating into pro‐proliferative Afplow and pro‐survival Afphigh subpopulations.
Ting Fang   +12 more
wiley   +1 more source

Cidea Targeting Protects Cochlear Hair Cells and Hearing Function From Drug‐ and Noise‐Induced Damage

open access: yesAdvanced Science, EarlyView.
Acquired sensorineural hearing loss is primarily caused by the damage or loss of cochlear hair cells, induced by factors such as noise exposure and ototoxic drugs. The deficiency of apoptosis‐inducing gene Cidea in Cidea KO mice or by delivering CRISPR/SlugCas9‐HF via AAV to edit Cidea effectively alleviated hair cell damage and hearing loss caused by ...
Shasha Zhang   +14 more
wiley   +1 more source

Automatic determination of fat in milk by use of a flow injection system with a piezoelectric detector

open access: green, 2000
Lisbeth Manganiello   +4 more
openalex   +2 more sources

Smart Nanoparticles Disrupting Energy Supply through Triple Mechanisms to Kill Tumors via Dual Disruption of Mitochondria and Lysosomes

open access: yesAdvanced Science, EarlyView.
This study introduces a biomimetic nanoplatform (MTCA@C) designed for precise cancer therapy. It targets mitochondria to induce dysfunction through photodynamic activation, while concurrently blocking mitophagy via lysosomal alkalinization. The platform further triggers methuosis, resulting in tumor cell death through vacuolization and energy pathway ...
Xiao Xu   +6 more
wiley   +1 more source

Gabpα‐Pparγ Complex Determines Glycolytic Capacity and Lactic Acid Homeostasis in Brown Fat

open access: yesAdvanced Science, EarlyView.
This study identifies the Gabpα–Pparγ complex as a key transcriptional regulator that couples glycolysis to lactate‐driven thermogenesis in brown adipose tissue by directly activating Eno1 transcription. ‌Competitive disruption of this interaction impairs lactate metabolism and thermogenic capacity.
Zhihan Wang   +22 more
wiley   +1 more source

Home - About - Disclaimer - Privacy