<i>In Vitro</i> Gastrointestinal Digestion of Fresh Cheese: Effect of ω-3 Fatty Acids and Milk Fat Globule Membrane Enrichment on Nutrient Digestibility and Antioxidant Activity. [PDF]
Hueso D +6 more
europepmc +1 more source
Nanoparticle Immunoadjuvant Complexes Augment Germinal Center Responses to Vaccination
Scaffolding IL‐21 on the surface of a self‐assembling nanoparticle immunogen drives improved germinal center and humoral immune responses. These nanoparticle immunoadjuvant complexes (NICs) functionally modulate the germinal center driving improved somatic hypermutation and antibody maturation, suggesting this platform has potential utility as a ...
Nicholas J. Tursi +21 more
wiley +1 more source
Milk fat globule membrane ameliorates depressive-like behaviors in chronic unpredictable mild stress rats by modulating the microbiota-gut-brain axis. [PDF]
Huang L +13 more
europepmc +1 more source
Comparative Single‐Cell Transcriptomic Atlas Reveals the Genetic Regulation of Reproductive Traits
A cross‐species single‐cell transcriptomic atlas of reproductive and central nervous system tissues from sheep and humans reveals conserved cellular programs and regulatory networks that regulated fertility. Integration with GWAS for sheep lifetime average litter size identifies UNC5–SLIT–BMP signaling as a core pathway coordinating neuroendocrine ...
Bingru Zhao +8 more
wiley +1 more source
CRISPR/Cas9-Mediated <i>TARDBP</i> Knockout Reduces Triacylglycerol Content and Key Milk Fat Metabolism Gene Expression in MAC-T Cells. [PDF]
Zhang Y +10 more
europepmc +1 more source
A multifunctional mPDZM nanoplatform is developed in this study. mPDZM integrates chemotherapy‐induced senescence, selective senolysis, and STING‐mediated immune activation. mPDZM effectively clears senescent tumor cells, remodels the tumor immune microenvironment, and enhances antitumor T‐cell responses.
Shiji Fang +17 more
wiley +1 more source
Characterization of mammary glands and milk fat globule transcripts in lactating buffalo and goats. [PDF]
Jiang H +11 more
europepmc +1 more source

