Results 91 to 100 of about 273,070 (316)

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

open access: yesAdvanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio   +11 more
wiley   +1 more source

Opportunities to Improve Milk Quality

open access: yesJournal of Food Protection, 1979
Many opportunities exist to improve the bacterial quality of milk, particularly of manufacturing-grade milk. Test results, using plate counting procedures by 10 Iowa dairy laboratories, reflect a gradual improvement in recent years in manufacturing-grade milk quality.
openaire   +2 more sources

High‐Temperature Phase Transformation in a V‐9Si‐6.5B Alloy: The Kinetic and Crystallographic Pathway From V5SiB2 to V8SiB4

open access: yesAdvanced Engineering Materials, EarlyView.
In situ synchrotron high‐energy X‐ray diffraction reveals the real‐time high‐temperature phase evolution of a ternary V‐9Si‐6.5B alloy. The study uncovers a kinetically delayed V5SiB2 → V8SiB4 transformation governed by massive structural and chemical barriers.
Zahra Sabeti   +4 more
wiley   +1 more source

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

open access: yesAdvanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo   +7 more
wiley   +1 more source

Electrostatically‐Stabilized PEG‐Free Lipid Nanoparticles for Systemic Nucleic Acid Delivery

open access: yesAdvanced Functional Materials, EarlyView.
This work describes non‐PEGylated layered lipid nanoparticles (nonPEG LLNPs), a gene delivery platform that improves upon standard PEGylated LNPs via electrostatic adsorption of charged polymers. nonPEG LLNPs maintain colloidal stability under biological stresses, enhance circulation time, and mitigate accelerated blood clearance and hepatic ...
Namita Nabar   +4 more
wiley   +1 more source

Long-Term Feeding of Dairy Goats with Broccoli By-Product and Artichoke Plant Silages: Milk Yield, Quality and Composition [PDF]

open access: gold, 2020
Paula Monllor   +6 more
openalex   +1 more source

Halide Perovskite Integrated Photovoltaic Cathodes Incorporating Pt on ZIF‐8‐Derived Carbon for Solar Hydrogen Production

open access: yesAdvanced Functional Materials, EarlyView.
A low‐Pt catalyst supported on zeolitic imidazolate framework (ZIF‐8)‐derived porous carbon and graphite is integrated with a halide perovskite photovoltaic, yielding cathodes that achieve a high photocurrent density (∼20 mA cm−2) under simulated sunlight and exhibit remarkable stability in acidic media over several days, thereby demonstrating a ...
Na Yeong Oh   +12 more
wiley   +1 more source

Reconfigurable Au Nanoparticle Monolayers on Regenerated Cellulose Hydrogels: Highly Sensitive SERS Detection of Polystyrene Micro/Nanoplastics With Interpretable Deep Learning

open access: yesAdvanced Functional Materials, EarlyView.
A regenerated cellulose (RC) hydrogel‐based SERS substrate integrating a Marangoni‐transferred gold nanoparticle self‐assembled monolayer (Au‐SAM) is fabricated. Reswelling‐induced hotspot formation enhances polystyrene micro/nanoplastics (PS MNPs) detection in complex matrices, providing reproducible, high‐throughput SERS signals across diverse ...
Youngho Jeon   +5 more
wiley   +1 more source

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