Results 71 to 80 of about 28,645 (286)

The connection between the host halo and the satellite galaxies of the Milky Way [PDF]

, 2016
Many properties of the Milky Way's dark matter halo, including its mass assembly history, concentration, and subhalo population, remain poorly constrained.
Benson, Andrew, Boylan-Kolchin, Michael, Lu, Yu, Mao, Yao-Yuan, Peter, Annika H. G., Tonnesen, Stephanie, Wechsler, Risa H., Wetzel, Andrew R.   +7 more
core   +3 more sources

Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53

Advanced Science, EarlyView.
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore, Andrea Basile, Stefano Freddi, Irene Schiano Lomoriello, Carlo Ribelle Zucca, Giuseppe Ciossani, Luigi Scietti, Alessandro Cuomo, Simona Ronzoni, Simone Pelicci, Mario Faretta, Elena Zaccheroni, Giuliana Pelicci, Vittoria Matafora, Angela Bachi, Rosalind Helen Gunby, Salvatore Pece, Sara Sigismund, Letizia Lanzetti, Ivan Nicola Colaluca, Pier Paolo Di Fiore   +20 more
wiley   +1 more source

Investigating halo substructures with annual modulation signature [PDF]

, 2006
Galaxy hierarchical formation theories, numerical simulations, the discovery of the Sagittarius Dwarf Elliptical Galaxy (SagDEG) in 1994 and more recent investigations suggest that the dark halo of the Milky Way can have a rich phenomenology containing ...
Belli, P., Bernabei, R., Cappella, F., Cerulli, R., Dai, C. J., Giuffrida, G., He, H. L., Incicchitti, A., Kuang, H. H., Ma, J. M., Martinez, M., Montecchia, F., Nozzoli, F., Prosperi, D., Sheng, X. D., Ye, Z. P.   +15 more
core   +2 more sources

On the edge: the relation between stellar and dark matter haloes of Milky Way-mass galaxies

Monthly Notices of the Royal Astronomical Society, 2023
ABSTRACTWe investigate the build-up of the accreted stellar and dark matter haloes of Milky Way-like galaxies in APOSTLE suite of cosmological hydrodynamics simulations. We show that the stellar halo is made up primarily of stars stripped from a small number of massive dwarfs, most of which are disrupted by the present day. The dark matter halo, on the
A Genina, A J Deason, C S Frenk
openaire   +4 more sources

CRP Deficiency Rescues Periodontitis‐Induced Hippocampal Neurogenesis Impairment by Suppressing OPC‐Derived BMP4 Signaling in Rats

Advanced Science, EarlyView.
Chronic periodontitis elevates circulating CRP, which enters the hippocampus to upregulate BMP4 in oligodendrocyte precursor cells (OPCs), thereby impairing neurogenesis and inducing anxiety/depression‐like behaviors in rats. Counteracting this pathway, CRP deficiency helps confer functional resilience to OPCs.
Lingjie Li, Ping Deng, Siyu Hou, Xianbo Xia, Wei Zhao, Xingyu Zhu, Yang Zhang, Chao Wang, Ling Xu, Jinlin Song   +9 more
wiley   +1 more source

Assembly of the outer Galactic stellar halo in the hierarchical model

, 2010
We provide a set of numerical N-body simulations for studying the formation of the outer Milky Ways's stellar halo through accretion events. After simulating minor mergers of prograde and retrograde orbiting satellite halo with a Dark Matter main halo ...
Adelman-McCarthy, Belokurov, Binney, Boylan-Kolchin, Bullock, Chiba, Curir, Grillmair, Huang, Miceli, Moore, Navarro, Press, White, Yanny, Zolotov   +15 more
core   +1 more source

Fibronectin1‐Expressing Subicular Circuits Selectively Govern the Retrieval of Novel Object Recognition

Advanced Science, EarlyView.
Fibronectin 1 (FN1)‐expressing subicular subpopulations encode novel object preference and selectively govern retrieval of novel object recognition (NOR) via affecting excitability of entorhinal‐projecting circuit through large conductance Ca2+‐activated potassium (BK) channel. ABSTRACT Novel object recognition (NOR), referring to the cognitive ability
Fan Fei, Jiaying Shi, Jing Xi, Yixiang Xu, Shuye Ying, Xukun Fan, Wangjialu Lu, Zhisheng Li, Menghan Li, Yu Wang, Li Cheng, Lin Yang, Lingyu Xu, Zhong Chen, Cenglin Xu, Yi Wang   +15 more
wiley   +1 more source

Minimum-entropy Constraints on Galactic Potentials

The Astrophysical Journal
A tracer sample in a gravitational potential, starting from a generic initial condition, phase-mixes toward a stationary state. This evolution is accompanied by an entropy increase, and the final state is characterized by a distribution function (DF ...
Leandro Beraldo e Silva, Monica Valluri, Eugene Vasiliev, Kohei Hattori, Walter de Siqueira Pedra, Kathryne J. Daniel   +5 more
doaj   +1 more source

Tilted Dark Halos Are Common and Long-lived, and Can Warp Galactic Disks

The Astrophysical Journal Letters, 2023
In the Lambda cold dark matter paradigm, the dark halo governs the gravitational potential within which a galaxy can form and evolve. In this Letter we show that the present-day inner ( r < 50 kpc) dark halo can be significantly misaligned with the ...
Jiwon Jesse Han, Vadim Semenov, Charlie Conroy, Lars Hernquist   +3 more
doaj   +1 more source

Testing two alternatives theories to dark matter with the Milky Way dynamics

, 2015
Two alternative theories to dark matter are investigated by testing their ability to describe consistently the dynamics of the Milky Way. The first one refers to a modified gravity theory having a running gravitational constant and the second assumes ...
de Oliveira, P. L. C., Pacheco, J. A. de Freitas, Reinisch, G.   +2 more
core   +1 more source