Results 131 to 140 of about 3,194 (299)
Understanding the Milky Way with Stars
"How do galaxies form?" is one of the most important questions in modern astrophysics. Hierarchical growth, the most plausible theory behind galaxy formation, suggests that galaxies, including the Milky Way, assemble through the accretion of smaller ...
Ou, Xiaowei
core
Early Coformation of the Milky Way’s Thin and Thick Disks at Redshift z > 2
The Astrophysical JournalThe Milky Way serves as a template for understanding the formation and evolution of late-type massive disk galaxies since we can obtain detailed chemical and kinematic information for large samples of individual stars. However, the early formation of the
Lais Borbolato +10 more
doaj +1 more source
Advanced Science, EarlyView.ABSTRACT Inflammatory bowel disease (IBD) is characterized by dysregulated T cell responses. RNA helicases, including DExD‐box helicase 21 (DDX21), are pivotal in RNA metabolism, but their role in T cell‐mediated pathology during IBD remains unclear. Here, we demonstrate that DDX21 expression in CD4+ T cells correlates with cell cycle and translation ...
Yujuan Zhang +11 more
wiley +1 more source
The Astrophysical JournalAge is the most difficult fundamental stellar parameter to infer for isolated stars. While isochrone-based ages are in general imprecise for both main-sequence dwarfs and red giants, precise isochrone-based ages can be obtained for stars on the subgiant ...
David M. Nataf +3 more
doaj +1 more source
PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe
Advanced Science, EarlyView.This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao +14 more
wiley +1 more source
Stellar Paternity Tests: Matching High-latitude B Stars to the Open Clusters of their Birth
The Astrophysical JournalOB stars generally form in open clusters within the Milky Way’s thin disk, so when they are found at high Galactic latitudes, it is thought that they were ejected from their birth clusters during the past few tens of millions of years.
Brandon Schweers, M. Virginia McSwain
doaj +1 more source
Advanced Science, EarlyView.Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng +8 more
wiley +1 more source
Formation of the Two-armed Phase Spiral from Multiple External Perturbations
The Astrophysical JournalRecent studies using the Gaia DR3 data have revealed a two-armed phase spiral in the Z – V _Z phase space in the inner disk. In this study, we present new features of the two-armed phase spiral revealed by the Gaia data and a new mechanism to explain ...
Junxian Lin +5 more
doaj +1 more source
The Chemo-Dynamical Evolution Of The Milky Way Disc
, 2016 The kinematic properties of the stellar subpopulations in the Milky Way disc are linked to their radial and vertical scale lengths. On the other hand, element abundances and abundance ratios are a signature of the evolution history of the stellar components.
openaire +2 more sources
Advanced Science, EarlyView.Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu +18 more
wiley +1 more source