Results 141 to 150 of about 3,194 (299)

Sex‐Specific Regulation of Glycemic Homeostasis by Theabrownin from Pu‐erh Tea

Advanced Science, EarlyView.
Pu‐erh tea's key component, theabrownin (TB), lowers blood glucose in a sex‐specific manner. In females, estrogen boosts intestinal MUC2 production, which dramatically enhances TB's ability to inhibit the carbohydrate‐digesting enzyme α‐glucosidase.
Yang Li, Junliang Kuang, Dan Zheng, Jieyi Wang, Kun Ge, Chun Qu, Xiaojiao Zheng, Zhenxing Ren, Fengjie Huang, Mingliang Zhao, Yimin Sun, Huiheng Zhang, Keke Ding, Xixi Xia, Yajun Tang, Lu Liu, Jian Zhou, Fei Gao, Xiaohui Ma, Yongquan Xu, Guoxiang Xie, Aihua Zhao, Wei Jia   +22 more
wiley   +1 more source

Four-hundred Very Metal-poor Stars Studied with LAMOST and Subaru. III. Dynamically Tagged Groups and Chemodynamical Properties

The Astrophysical Journal
Very metal-poor (VMP) stars record the signatures of early accreted galaxies, making them essential tools for unraveling the early stages of Galaxy formation.
Ruizhi Zhang, Tadafumi Matsuno, Haining Li, Wako Aoki, Xiang-Xiang Xue, Takuma Suda, Gang Zhao, Yuqin Chen, Miho N. Ishigaki, Jianrong Shi, Qianfan Xing, Jingkun Zhao   +11 more
doaj   +1 more source

Dynamical modelling of the Milky Way Bar/Bulge

, 2019
I review the recent progresses on the properties of the Galactic bar and bulge, and the major theoretical models and techniques to understand the Milky Way bulge. Despite these recent advances, a complete bulge formation model that explains the full kinematics and metallicity distribution is still not fully understood.
openaire   +2 more sources

A Soft, Flexible Implant for Wireless Photothermal–Pyroelectric Neurostimulation

Advanced Science, EarlyView.
A replication strategy is used to enlarge the exposed surface area of barium titanate within flexible films with embedded carbon nanotubes, enabling efficient photothermal‐pyroelectric stimulation. Polar crystalline nanosheets show superior performance in guiding neural progenitor cells toward neuronal differentiation.
Jiang Wu, Minmin Mao, Beltzane Garcia Cirera, Hao Ye, Xiangzhong Chen, Josep Puigmartí‐Luis, Ni Qin, Salvador Pané   +7 more
wiley   +1 more source

The Rotating Bulge and Halo in the Milky Way: Evidence of Angular Momentum Transferred from the Decelerating Bar

The Astrophysical Journal
Recent observations indicate that both the Milky Way bulge and inner halo exhibit angular momentum, although the origin and evolution of this prograde signature remain ambiguous.
Zhuohan Li, Chengdong Li, Gang Zhao, Ruizhi Zhang, Xiang-Xiang Xue   +4 more
doaj   +1 more source

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

Advanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang, Cancan Yao, Yan Chen, Ke Cai, Zhouping Lu, Boxuan Wu, Kun Yu, Yan Shi, Jianyuan Zhao, Xiangyu Zhou   +9 more
wiley   +1 more source

The effect of environment on the mass assembly history of the Milky Way and M31

International audienceWe study the mass growth histories of the halos of Milky Way and M31 analogues formed in constrained cosmological simulations of the Local Group.
Ewoud Wempe, White, Simon D.M, Lavaux, G., Jasche, J., Helmi, Amina, Simon D.M. White, Lavaux, Guilhem, Wempe, Ewoud, Wempe, E., White, S., Jasche, Jens, Jens Jasche, Amina Helmi, Guilhem Lavaux, Helmi, A.   +14 more
core   +1 more source

Characteristic radii of the Milky Way globular clusters

, 2019
We report on the extent of the effects of the Milky Way gravitational field in shaping the structural parameters and internal dynamics of its globular cluster population.We make use of a homogeneous, up-to-date data set with kinematics, structural ...
Carlberg, Raymond G., Webb, Jeremy J., Piatti, Andres Eduardo   +2 more
core   +1 more source

He Awa Whiria: The Tidal Streams of Interstellar Objects

The Astrophysical Journal
Upcoming surveys are likely to discover a new sample of interstellar objects (ISOs) within the solar system, but questions remain about the origin and distribution of this population within the Galaxy.
John C. Forbes, Michele T. Bannister, Chris Lintott, Angus Forrest, Simon Portegies Zwart, Rosemary C. Dorsey, Leah Albrow, Matthew J. Hopkins   +7 more
doaj   +1 more source

Tumor‐Derived LAMB3 Drives Immunosuppressive LRRC15+ Fibroblast Formation During Pancreatic Ductal Adenocarcinoma Development

Advanced Science, EarlyView.
A single‐cell atlas of pancreatic ductal adenocarcinoma development reveals progressive ductal‐fibroblast‐immune crosstalk. Tumor‐derived LAMB3 drives the formation of immunosuppressive LRRC15+ fibroblasts through the ITGB1/FAK/MAPK/FOSL2 signaling. Glycolytic reprogramming upregulates LAMB3 and correlates with LRRC15+ fibroblast enrichment.
Xuqing Shi, Hangqi Liu, Jianru Sun, Xiaoding Liu, Xinping Jv, Longyun Chen, Yuhan Zhang, Hui Zhang, Xudong Xing, Ruiyu Li, Xinyi Ke, Jun Wang, Xianglin Yin, Bohan Liu, Qixian Liu, Yuan Wang, Junliang Lu, Shiyi Liu, Junyi Pang, Yumeng Cai, Menghua Dai, Fan Bai, Huanwen Wu, Zhiyong Liang   +23 more
wiley   +1 more source