Results 61 to 70 of about 45,061 (325)

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

open access: yesAdvanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio   +11 more
wiley   +1 more source

Mapping the Hidden Universe: The Galaxy Distribution in the Zone of Avoidance [PDF]

open access: yes, 1999
Due to the foreground extinction of the Milky Way, galaxies become increasingly faint as they approach the Galactic Equator creating a ``zone of avoidance'' (ZOA) in the distribution of optically visible galaxies of about 25%.
Cameron   +21 more
core   +2 more sources

Dynamical evidence of the age-metallicity relation in the Milky Way disk [PDF]

open access: yesAstronomy & Astrophysics, 2006
We studied the relationship between the average stellar abundance of several elements and the orbital evolution of stars in the neighbourhood of the Sun, using both observational data for 325 late-type dwarfs in a volume-complete sample and simulations of the orbital diffusion.
Rocha-Pinto, H. J.   +4 more
openaire   +2 more sources

NanoMOF‐Based Multilevel Anti‐Counterfeiting by a Combination of Visible and Invisible Photoluminescence and Conductivity

open access: yesAdvanced Functional Materials, EarlyView.
This study presents novel anti‐counterfeiting tags with multilevel security features that utilize additional disguise features. They combine luminescent nanosized Ln‐MOFs with conductive polymers to multifunctional mixed‐matrix membranes and powder composites. The materials exhibit visible/NIR emission and matrix‐based conductivity even as black bodies.
Moritz Maxeiner   +9 more
wiley   +1 more source

Minimum-entropy Constraints on Galactic Potentials

open access: yesThe Astrophysical Journal
A tracer sample in a gravitational potential, starting from a generic initial condition, phase-mixes toward a stationary state. This evolution is accompanied by an entropy increase, and the final state is characterized by a distribution function (DF ...
Leandro Beraldo e Silva   +5 more
doaj   +1 more source

The Milky Way's bright satellites as an apparent failure of LCDM

open access: yes, 2012
We use the Aquarius simulations to show that the most massive subhalos in galaxy-mass dark matter halos in LCDM are grossly inconsistent with the dynamics of the brightest Milky Way dwarf spheroidal galaxies.
Ando   +135 more
core   +1 more source

Dark Matter distribution in the Milky Way: microlensing and dynamical constraints [PDF]

open access: yesJournal of Cosmology and Astroparticle Physics, 2011
We show that current microlensing and dynamical observations of the Galaxy permit to set interesting constraints on the Dark Matter local density and profile slope towards the galactic centre. Assuming state-of-the-art models for the distribution of baryons in the Galaxy, we find that the most commonly discussed Dark Matter profiles (viz. Navarro-Frenk-
Iocco F., Pato M., Bertone G., Jetzer P.
openaire   +4 more sources

Reconfigurable Nucleic Acid Nanoparticles with Therapeutic RNAi Responses to Intracellular Disease Markers

open access: yesAdvanced Functional Materials, EarlyView.
Many known diseases arise from dysregulated gene expression, and differentially expressed genes can serve as biomarkers to distinguish diseased cells from healthy tissues. In this study, reconfigurable nucleic acid nanoparticles (recNANPs) are introduced that can detect overexpressed cancer biomarkers and subsequently release RNAi inducers to silence ...
Yelixza I. Avila   +7 more
wiley   +1 more source

On the Migration Origin of the Hercules Moving Group with GAIA, LAMOST, APOGEE, and GALAH Surveys

open access: yesThe Astrophysical Journal, 2023
Using Gaia DR3 data and the wavelet transformation technique, we study the substructures of the Hercules moving group (HMG): Hercules 1 (H1) and Hercules 2 (H2).
Xilong Liang   +5 more
doaj   +1 more source

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