Results 61 to 70 of about 540,184 (283)

Biomimetic Co‐delivery of Lenvatinib and FePt Nanoparticles for Enhanced Ferroptosis/Apoptosis Treatment of Hepatocellular Carcinoma

Advanced Healthcare Materials, EarlyView.
This study introduces a novel HCC treatment using poly lactic‐co‐glycolic acid (PLGA) nanoparticles encased in HCC cell membranes to co‐deliver Lenvatinib and FePt nanoparticles. This approach improves treatment efficacy by enhancing ferroptosis and apoptosis.
Feichao Xuan, Xingyang Zhao, Weiran Pang, Zirong Li, Xiangyi Yin, Weizhong Xie, Xiaojun Zeng, Liming Nie, Junying Yang, Shiying Li, Puxiang Lai, Chihua Fang   +11 more
wiley   +1 more source

Radial Wave in the Galactic Disk: New Clues to Discriminate Different Perturbations

The Astrophysical Journal
Decoding the key dynamical processes that shape the Galactic disk structure is crucial for reconstructing the Milky Way’s evolution history. The second Gaia data release unveils a novel wave pattern in the L _Z −〈 V _R 〉 space, but its formation ...
Chengye Cao, Zhao-Yu Li, Ralph Schönrich, Teresa Antoja   +3 more
doaj   +1 more source

Precision Photothermal Therapy at Mild Temperature: NIR‐II Imaging‐Guided, H2O2‐Responsive Stealth Nanobomb

Advanced Healthcare Materials, EarlyView.
The new generation nanobomb, termed the stealth nanobomb, is fabricated through self‐assembly using a polymeric carbon monoxide carrier (PLGA(CO)), small molecule near‐infrared‐active agents (2TT‐OC46B), and phospholipid polyethylene glycol (DSPE‐mPEG2000). The stealth nanobomb can circulate in the bloodstream and specifically target pancreatic cancer,
Gongcheng Ma, Qihang Ding, Yue Wang, Zhiwei Zhang, Yuding Zhang, Hui Shi, Lintao Cai, Ping Gong, Pengfei Zhang, Zhen Cheng, Jong Seung Kim   +10 more
wiley   +1 more source

The Maximum Optical Depth Towards Bulge Stars From Axisymmetric Models of the Milky Way [PDF]

, 1997
It has been known that recent microlensing results towards the bulge imply mass densities that are surprisingly high given dynamical constraints on the Milky Way mass distribution. We derive the maximum optical depth towards the bulge that may be generated by axisymmetric structures in the Milky Way, and show that observations are close to surpassing ...
arxiv   +1 more source

Probiotic‐Based Mineralized Living Materials to Produce Antimicrobial Yogurts

Advanced Healthcare Materials, EarlyView.
The self‐assembly and mineralization of collagen in the presence of probiotics produces hybrid living materials that hosts and protects the cells. Intra‐ and interfibrillar mineralization of collagen fibers, as occurring in bone, results, respectively, in a bulk and single‐cell protective layer of cells, that survive in simulated gastric conditions and,
Gloria B. Ramírez‐Rodríguez, Laura Sabio, Laura Cerezo‐Collado, Víctor Garcés, Jose M. Domínguez‐Vera, José M. Delgado‐López   +5 more
wiley   +1 more source

A Tale of Tidal Tails in the Milky Way [PDF]

, 2014
Hundreds of globular clusters and dwarf galaxies encircle the Milky Way. Many of these systems have undergone partial disruption due to tidal forces, littering the halo with stellar streams. These tidal tails are sensitive to the Galactic potential, facilitating an excellent laboratory to investigate Galaxy formation and evolution, as well as local ...
arxiv   +1 more source

Pushing Radiative Cooling Technology to Real Applications

Advanced Materials, EarlyView.
Radiative cooling controls surface optical properties for solar and thermal radiation, offering solutions for global warming and energy savings. Despite significant advances, key challenges remain: optimizing optical efficiency, maintaining aesthetics, preventing overcooling, enhancing durability, and enabling scalable production.
Chongjia Lin, Keqiao Li, Meng Li, Benjamin Dopphoopha, Jiongzhi Zheng, Jiazheng Wang, Shanshan Du, Yang Li, Baoling Huang   +8 more
wiley   +1 more source

The Milky Way's nuclear star cluster and massive black hole [PDF]

, 2015
Because of its nearness to Earth, the centre of the Milky Way is the only galaxy nucleus in which we can study the characteristics, distribution, kinematics, and dynamics of the stars on milli-parsec scales. We have accurate and precise measurements of the Galactic centre's central black hole, Sagittarius A*, and can study its interaction with the ...
arxiv   +1 more source

Porous Silicon Nanoneedles Efficiently Deliver Adenine Base Editor to Correct a Recurrent Pathogenic COL7A1 Variant in Recessive Dystrophic Epidermolysis Bullosa

Advanced Materials, EarlyView.
Base editing using nanoneedles efficiently corrects pathogenic variants in the type VII collagen gene of primary fibroblasts from patients with recessive dystrophic epidermolysis bullosa. Nanoneedle editing induces minimal and reversible transcriptional perturbations while restoring the production and secretion of functional type VII collagen.
Salman Ahmad Mustfa, Marija Dimitrievska, Cong Wang, Chenlei Gu, Ningjia Sun, Katarzyna Romańczuk, Pawel Karpinski, Łukasz Łaczmański, John A. McGrath, Joanna Jacków‐Malinowska, Ciro Chiappini   +10 more
wiley   +1 more source

Hydrogel‐Impregnated Robust Interlocking Nano Connector (HiRINC) for Noninvasive Anti‐Migration of Esophageal Stent

Advanced Materials, EarlyView.
The development of hydrogel‐impregnated robust interlocking nano connector (HiRINC) aims to address stent migration by improving tissue adhesion and reducing mechanical mismatch in self‐expandable metallic stents (SEMSs). The network‐like porous layer of HiRINC enhances adhesion and energy dissipation, demonstrates through ex vivo and in vivo tests ...
Eunyoung Jeon, Song Hee Kim, Sukyoung Kim, Dae Sung Ryu, Ji Won Kim, Kayoung Kim, Do Hoon Kim, Jung‐Hoon Park, Joonseok Lee   +8 more
wiley   +1 more source