Results 91 to 100 of about 77,216 (325)

Mapping the Chemodynamics of the Galactic Disk Using the LAMOST and APOGEE Red Clump Stars

The Astrophysical Journal Supplement Series
A detailed measurement is made of the metallicity distributions, kinematics, and dynamics of the thin and thick disks across a large disk volume (5.0 ≤ R ≤ 15.0 kpc and ∣ Z ∣ ≤ 3.0 kpc) by using the LAMOST–APOGEE red clump stars.
Weixiang Sun, Han Shen, Biwei Jiang, Xiaowei Liu   +3 more
doaj   +1 more source

The Chemical Evolution of the Milky Way Galaxy

, 2021
The elemental abundance gradients of elements up to Zn are predicted using the N body Monte Carlo technique by developing homogenous and heterogeneous Galactic Chemical Evolution (GCE) simulations. In the case of homogeneous GCE models, the galaxy is radially divided into eight annular rings of 2 kpc width each at a distance of 2-18 kpc from the center
openaire   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Unveiling the time evolution of chemical abundances across the Milky Way disk with APOGEE [PDF]

, 2023
Bridget Ratcliffe, Ivan Minchev, F. Anders, Sergey Khoperskov, G. Guiglion, Tobias Buck, Kátia Cunha, A. B. A. Queiroz, Christian Nıtschelm, Szabolcs Mészáros, Matthias Steinmetz, Roelof S. de Jong, Samir Nepal, Richard R. Lane, Jennifer Sobeck   +14 more
openalex   +1 more source

Constraining Compact Object Formation with 2M0521

, 2019
We show that the recently discovered binary 2M05215658+4359220 (2M0521), comprised of a giant star (GS) orbiting a suspected black hole (BH) in a ~80 day orbit, may be instrumental in shedding light on uncertain BH-formation physics and can be a test ...
Andrews, Jeff J., Breivik, Katelyn, Chatterjee, Sourav   +2 more
core   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

A Galactic Self-portrait: Density Structure and Integrated Properties of the Milky Way Disk

The Astrophysical Journal
The evolutionary history of the Milky Way disk is imprinted in the ages, positions, and chemical compositions of individual stars. In this study, we derive the intrinsic density distribution of different stellar populations using the final data release ...
Julie Imig, Jon A. Holtzman, Gail Zasowski, Jianhui Lian, Nicholas F. Boardman, Alexander Stone-Martinez, J. Ted Mackereth, Moire K. M. Prescott, Rachael L. Beaton, Timothy C. Beers, Dmitry Bizyaev, Michael R. Blanton, Katia Cunha, José G. Fernández-Trincado, Catherine E. Fielder, Sten Hasselquist, Christian R. Hayes, Misha Haywood, Henrik Jönsson, Richard R. Lane, Steven R. Majewski, Szabolcs Mészáros, Ivan Minchev, David L. Nidever, Christian Nitschelm, Jennifer Sobeck   +25 more
doaj   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Four-hundred Very Metal-poor Stars Studied with LAMOST and Subaru. III. Dynamically Tagged Groups and Chemodynamical Properties

The Astrophysical Journal
Very metal-poor (VMP) stars record the signatures of early accreted galaxies, making them essential tools for unraveling the early stages of Galaxy formation.
Ruizhi Zhang, Tadafumi Matsuno, Haining Li, Wako Aoki, Xiang-Xiang Xue, Takuma Suda, Gang Zhao, Yuqin Chen, Miho N. Ishigaki, Jianrong Shi, Qianfan Xing, Jingkun Zhao   +11 more
doaj   +1 more source

On the origin of gaseous galaxy halos - Low-column density gas in the Milky Way halo

, 2011
Recent observations show that spiral galaxies are surrounded by extended gaseous halos as predicted by the hierarchical structure formation scenario.
Ben Bekhti, Ben Bekhti, Boomsma, Bottema, Bouché, Bregman, Brinchmann, Cen, Charlton, Churchill, Combes, Fraternali, Gardiner, Gould, Heesen, Kalberla, Kalberla, Kalberla, Kalberla, Lockman, McClure-Griffiths, McPhate, Nicastro, Oort, Oosterloo, Pietz, Predehl, Richter, Richter, Richter, Rossa, Sancisi, Sancisi, Sembach, Shapiro, Swaters, Thilker, Thom, Wakker, Wakker, Wakker, Wakker, Westmeier, Whaley, Winkel   +44 more
core   +1 more source