Results 101 to 110 of about 155,710 (341)

The Extremely Metal-rich Knot of Stars at the Heart of the Galaxy

The Astrophysical Journal
We show with Gaia XP spectroscopy that extremely metal-rich (EMR) stars in the Milky Way ([M/H] _XP ≳ 0.5) are largely confined to a tight “knot” at the center of the Galaxy. This EMR knot is round in projection, has a fairly abrupt edge near R _GC,proj ∼
Hans-Walter Rix, Vedant Chandra, Gail Zasowski, Annalisa Pillepich, Sergey Khoperskov, Sofia Feltzing, Rosemary F. G. Wyse, Neige Frankel, Danny Horta, Juna Kollmeier, Keivan Stassun, Melissa K. Ness, Jonathan C. Bird, David Nidever, José G. Fernández-Trincado, João A. S. Amarante, Chervin F. P. Laporte, Jianhui Lian   +17 more
doaj   +1 more source

The origin and evolution of r- and s-process elements in the Milky Way stellar disk [PDF]

, 2015
Knowledge of abundance ratios as functions of metallicity can lead to insights on the origin and evolution of our Galaxy and its stellar populations. We aim to trace the chemical evolution of the neutron-capture elements Sr, Zr, La, Ce, Nd, Sm, and Eu in
C. Battistini, T. Bensby
semanticscholar   +1 more source

Contrasting the chemical evolution of the Milky Way and Andromeda [PDF]

Monthly Notices of the Royal Astronomical Society, 2005
The chemical evolution history of a galaxy hides clues about how it formed and has been changing through time. We have studied the chemical evolution history of the Milky Way (MW) and Andromeda (M31) to find which are common features in the chemical evolution of disc galaxies as well as which are galaxy-dependent.
Renda, Agostino, Kawata, Daisuke, Fenner, Yeshe, Gibson, Brad K.   +3 more
openaire   +4 more sources

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

The Dependence of Iron-rich Metal-poor Star Occurrence on Galactic Environment Supports an Origin in Thermonuclear Supernova Nucleosynthesis

The Astronomical Journal, 2023
It has been suggested that a class of chemically peculiar metal-poor stars called iron-rich metal-poor (IRMP) stars formed from molecular cores with metal contents dominated by thermonuclear supernova nucleosynthesis.
Zachary Reeves, Kevin C. Schlaufman, Henrique Reggiani   +2 more
doaj   +1 more source

Chemical evolution of the Galactic bulge as traced by microlensed dwarf and subgiant stars. VI. Age and abundance structure of the stellar populations in the central sub-kpc of the Milky Way [PDF]

, 2017
We present a detailed elemental abundance study of 90 F and G dwarf, turn-off and subgiant stars in the Galactic bulge. Based on high-resolution spectra acquired during gravitational microlensing events, stellar ages and abundances for 11 elements (Na ...
T. Bensby, S. Feltzing, Alan Gould, Alan Gould, A. Gould, J. Yee, Julie A. Johnson, M. Asplund, J. Meléndez, S. Lucatello, L. Howes, A. McWilliam, A. Udalski, M. Szymański, I. Soszyński, R. Poleski, R. Poleski, Ł. Wyrzykowski, K. Ulaczyk, K. Ulaczyk, S. Kozłowski, P. Pietrukowicz, J. Skowron, P. Mróz, M. Pawlak, F. Abe, Y. Asakura, A. Bhattacharya, I. Bond, D. Bennett, Y. Hirao, M. Nagakane, N. Koshimoto, T. Sumi, D. Suzuki, P. Tristram   +35 more
semanticscholar   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

What Is Missing from the Local Stellar Halo?

The Astrophysical Journal
The Milky Way’s stellar halo, which extends to >100 kpc, encodes the evolutionary history of our Galaxy. However, most studies of the halo to date have been limited to within a few kiloparsecs of the Sun.
Katherine Sharpe, Rohan P. Naidu, Charlie Conroy   +2 more
doaj   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

The Milky Way’s Rowdy Neighbors: The Effects of the Large Magellanic Cloud and Sagittarius Dwarf on the Milky Way Disk

The Astrophysical Journal
The Milky Way (MW) is a barred spiral galaxy shaped by tidal interactions with its satellites. The Large Magellanic Cloud (LMC) and the Sagittarius dwarf galaxy (Sgr) are the dominant influences at the present day. This paper presents a suite of four 10 ^
Ioana A. Stelea, Jason A. S. Hunt, Kathryn V. Johnston   +2 more
doaj   +1 more source