Results 101 to 110 of about 76,255 (323)

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

open access: yesAdvanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio   +11 more
wiley   +1 more source

Four-hundred Very Metal-poor Stars Studied with LAMOST and Subaru. III. Dynamically Tagged Groups and Chemodynamical Properties

open access: yesThe Astrophysical Journal
Very metal-poor (VMP) stars record the signatures of early accreted galaxies, making them essential tools for unraveling the early stages of Galaxy formation.
Ruizhi Zhang   +11 more
doaj   +1 more source

Gas Loss by Ram Pressure Stripping and Internal Feedback From Low Mass Milky Way Satellites

open access: yes, 2016
The evolution of dwarf satellites of the Milky Way is affected by the combination of ram pressure and tidal stripping, and internal feedback from massive stars.
Emerick, Andrew   +3 more
core   +1 more source

NanoMOF‐Based Multilevel Anti‐Counterfeiting by a Combination of Visible and Invisible Photoluminescence and Conductivity

open access: yesAdvanced Functional Materials, EarlyView.
This study presents novel anti‐counterfeiting tags with multilevel security features that utilize additional disguise features. They combine luminescent nanosized Ln‐MOFs with conductive polymers to multifunctional mixed‐matrix membranes and powder composites. The materials exhibit visible/NIR emission and matrix‐based conductivity even as black bodies.
Moritz Maxeiner   +9 more
wiley   +1 more source

SF-R You Sure? The Conflicting Role of Star Formation Rates in Constraining the Evolution of Milky Way Analogs in Cosmological Simulations

open access: yesThe Astrophysical Journal
Milky Way analogs (MWAs) have long been studied by astronomers to place our Galaxy within an extragalactic context. With the power of cosmological simulations, we are now able to not only characterize MWAs today, but also watch as they evolve through ...
Alicia M. Savelli   +4 more
doaj   +1 more source

Reconfigurable Nucleic Acid Nanoparticles with Therapeutic RNAi Responses to Intracellular Disease Markers

open access: yesAdvanced Functional Materials, EarlyView.
Many known diseases arise from dysregulated gene expression, and differentially expressed genes can serve as biomarkers to distinguish diseased cells from healthy tissues. In this study, reconfigurable nucleic acid nanoparticles (recNANPs) are introduced that can detect overexpressed cancer biomarkers and subsequently release RNAi inducers to silence ...
Yelixza I. Avila   +7 more
wiley   +1 more source

A Galactic Self-portrait: Density Structure and Integrated Properties of the Milky Way Disk

open access: yesThe Astrophysical Journal
The evolutionary history of the Milky Way disk is imprinted in the ages, positions, and chemical compositions of individual stars. In this study, we derive the intrinsic density distribution of different stellar populations using the final data release ...
Julie Imig   +25 more
doaj   +1 more source

The Metallicity Distribution Function of Field Stars in M31's Bulge

open access: yes, 2005
We have used Hubble Space Telescope Wide Field Planetary Camera 2 observations to construct a color-magnitude diagram (CMD) for the bulge of M31 at a location ~1.6 kpc from the galaxy's center.
Ata Sarajedini   +4 more
core   +1 more source

FeDSNP‐Pa Nanoassemblies: A Triple‐Action Therapeutic Strategy Targeting Oxidative Stress, Inflammation, and Pyroptosis for Retinal Ganglion Cell Protection in Glaucoma

open access: yesAdvanced Functional Materials, EarlyView.
FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu   +5 more
wiley   +1 more source

Colloidal Opaline Composites as Throughput‐Scalable, Fully Transparent, and Color‐Tunable Radiative Cooling Exterior Films for Outdoor Photovoltaics

open access: yesAdvanced Functional Materials, EarlyView.
Particular thermal metamaterials are widely used as daytime radiative coolers merely by embedding thermally emissive nanoparticles (NPs) in liquid resins to form scalable, yet highly efficient cooling films in a cost‐effective way. However, randomly dispersed NPs, prevalently used thus far, cause strong scattering, limiting NP content and cooling ...
YongDeok Cho   +10 more
wiley   +1 more source

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