Results 111 to 120 of about 155,710 (341)
The Chemical Evolution of the Milky Way in a cosmological context [PDF]
EAS Publications Series, 2007 A short overview is presented of several topics concerning the evolution of the Milky Way (MW) in a cosmological context. In particular, the metallicity distribution of the MW halo is derived analytically and the halo metallicity and abundance patterns are compared to those of Local Group galaxies.
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Molecular Oncology, EarlyView.Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho +11 more
wiley +1 more source
The Stellar Disk Structure Revealed by the Mono-age Populations of the LAMOST Red Clump Star Sample
The Astronomical JournalUnderstanding the structure of the Galactic disk is crucial for understanding the formation and evolutionary history of the Milky Way. This study examines the structure of the Galactic disk by analyzing a sample of 138,667 primary red clump (RC) stars ...
Zheng Yu +4 more
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Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
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Mapping the Chemodynamics of the Galactic Disk Using the LAMOST and APOGEE Red Clump Stars
The Astrophysical Journal Supplement SeriesA detailed measurement is made of the metallicity distributions, kinematics, and dynamics of the thin and thick disks across a large disk volume (5.0 ≤ R ≤ 15.0 kpc and ∣ Z ∣ ≤ 3.0 kpc) by using the LAMOST–APOGEE red clump stars.
Weixiang Sun +3 more
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Molecular Oncology, EarlyView.TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach +8 more
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The Astrophysical JournalVery metal-poor (VMP) stars record the signatures of early accreted galaxies, making them essential tools for unraveling the early stages of Galaxy formation.
Ruizhi Zhang +11 more
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The early phases of Milky Way's chemical evolution [PDF]
Nuclear Physics A, 2005 10 pages, 4 figures, Review talk in Nuclei in the Cosmos VIII (Eds. L.
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The chemical evolution of the Milky Way: the Three Infall Model [PDF]
Monthly Notices of the Royal Astronomical Society, 2013 12 pages, 7 figures, accepted for publication in ...
Donatella Romano +3 more
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Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source