Results 51 to 60 of about 77,216 (325)

Contrasting copper evolution in ω Centauri and the Milky Way [PDF]

Monthly Notices of the Royal Astronomical Society: Letters, 2007
Abstract Despite the many studies on stellar nucleosynthesis published so far, the scenario for the production of copper in stars remains elusive. In particular, it is still debated whether copper originates mostly in massive stars or in Type Ia supernovae.
Romano, Donatella, Matteucci, Francesca
openaire   +2 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Additional Evidence for the Existence of a Primordial Disk System

The Astrophysical Journal
The origin of very metal-poor (VMP; [Fe/H] ≤ −2.0) stars on planar orbits has been the subject of great attention since their first discovery. However, prior to the release of the Gaia BP/RP (XP) spectra and large photometric samples such as SkyMapper ...
Shuai Xu, Haibo Yuan, Bowen Huang, Timothy C. Beers, Yang Huang, Maosheng Xiang, Kai Xiao, Jihye Hong, Young Sun Lee, Wuming Yang   +9 more
doaj   +1 more source

Figure Rotation of IllustrisTNG Halos

The Astrophysical Journal, 2023
We use the TNG50 and TNG50 dark matter (DM)-only simulations from the IllustrisTNG simulation suite to conduct an updated survey of halo figure rotation in the presence of baryons.
Neil Ash, Monica Valluri
doaj   +1 more source

On the origin of fluorine in the Milky Way

, 2004
The main astrophysical factories of fluorine (19F) are thought to be Type II supernovae, Wolf-Rayet stars, and the asymptotic giant branch (AGB) of intermediate mass stars.
Agostino Renda, Alessandro Chieffi, Alibés, Allende Prieto, Amanda I. Karakas, Bekki, Bertelli, Brad K. Gibson, Cappellaro, Cunha, Dray, Fenner, Forestini, Frost, Frost, Gibson, Holweger, Iglesias, Iwamoto, John C. Lattanzio, Jorissen, Karakas, Karakas, Katia Cunha, Kroupa, Limongi, Lugaro, Meynet, Mowlavi, Myra, Rana, Renzini, Russell, Schaller, Simon Campbell, Smith, Timmes, Vassiliadis, Verne V. Smith, Woosley, Woosley, Woosley, Woosley, Yeshe Fenner   +43 more
core   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Constraining the Milky Way Halo Accretion History with Simulated Stellar Halos: Designing the HALO7D-X Survey

The Astrophysical Journal
We present the design for HALO7D-X, a survey of the stellar halo to investigate the accretion history of the Milky Way. The survey will use a combination of Hubble Space Telescope (HST) and Gaia data for sky position and proper motions of faint stars (18 
Miranda Apfel, Kevin McKinnon, Constance M. Rockosi, Puragra Guhathakurta, Kathryn V. Johnston   +4 more
doaj   +1 more source

Impact of AGB Stars on the Chemical Evolution of Neutron-Capture Elements

Universe, 2022
In this review, we discuss the impact of s-process nucleosynthesis in asymptotic giant branch stars on the enrichment of heavy elements. We review the main steps made on this subject in the last 40 years and discuss the importance of modelling the ...
Gabriele Cescutti, Francesca Matteucci
doaj   +1 more source

The formation and early evolution of the Milky Way [PDF]

Symposium - International Astronomical Union, 1985
In broad outline, the traditional picture for the formation of the Milky Way can be summarized as follows. The proto-galaxy consisted of a slowly rotating cloud of metal-free gas that cooled by bremsstrahlung and recombination radiation. As the internal pressure of the gas decreased, it collapsed in stages with smaller dimensions, faster rotation ...
openaire   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source