Results 71 to 80 of about 77,093 (285)

Evolution of the Milky Way halo by accretion of dwarf satellite galaxies

, 2011
Within the Cold Dark Matter scenario the hierarchical merging paradigm is the natural result to form massive galactic halos by the minor mergers of sub-halos and, by this, inherently their stellar halo.
Bouchard, Diemand, G. Hensler, Grebel, Johnston, M. Petrov, Mayer, Prantzos, Revaz, Tolstoy   +9 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

An Inward-moving and Asymmetric Velocity Wave Detected in LAMOST-Gaia

The Astrophysical Journal Letters
The phase space, as coded by kinematic parameters and chemical abundances, is crucial for understanding the formation of the Galactic disk. Using red giant stars from the Galactic thin disk with [Fe/H] > − 0.8 and low- α ratios identified in LAMOST-Gaia,
Yuqin Chen, Gang Zhao, Wenbo Wu, Zixi Guo, Haopeng Zhang, Zhuohan Li   +5 more
doaj   +1 more source

The chemodynamical evolution of the Milky Way disc -- A new modeling approach

, 2013
Despite the recent advancements in the field of galaxy formation and evolution, fully self-consistent simulations are still unable to make the detailed predictions necessary for the planned and ongoing large spectroscopic and photometry surveys of the ...
Chiappini, Cristina, Martig, Marie, Minchev, Ivan   +2 more
core   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

A 3D Chemodynamical Census of Inner-Galaxy Metal-poor Giants to [Fe/H] ∼ −3.5

The Astrophysical Journal Letters
The earliest assembly of the Milky Way remains poorly understood, yet the spatial, chemical, and kinematic properties of its most metal-poor stars provide a unique fossil record of its proto-Galaxy phase.
Shenglan Sun, Yang Huang, Fangzhou Jiang, Huawei Zhang, Xiang-Xiang Xue, Timothy C. Beers, Chengye Cao, Qikang Feng, Ruizhi Zhang, Haiyang Xing, João A. S. Amarante   +10 more
doaj   +1 more source

Gas Loss by Ram Pressure Stripping and Internal Feedback From Low Mass Milky Way Satellites

, 2016
The evolution of dwarf satellites of the Milky Way is affected by the combination of ram pressure and tidal stripping, and internal feedback from massive stars.
Emerick, Andrew, Gatto, Andrea, Grcevich, Jana, Mac Low, Mordecai-Mark   +3 more
core   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

The Extremely Metal-rich Knot of Stars at the Heart of the Galaxy

The Astrophysical Journal
We show with Gaia XP spectroscopy that extremely metal-rich (EMR) stars in the Milky Way ([M/H] _XP ≳ 0.5) are largely confined to a tight “knot” at the center of the Galaxy. This EMR knot is round in projection, has a fairly abrupt edge near R _GC,proj ∼
Hans-Walter Rix, Vedant Chandra, Gail Zasowski, Annalisa Pillepich, Sergey Khoperskov, Sofia Feltzing, Rosemary F. G. Wyse, Neige Frankel, Danny Horta, Juna Kollmeier, Keivan Stassun, Melissa K. Ness, Jonathan C. Bird, David Nidever, José G. Fernández-Trincado, João A. S. Amarante, Chervin F. P. Laporte, Jianhui Lian   +17 more
doaj   +1 more source

Cosmological pseudobulge formation

, 2012
Bulges can be classified into classical and pseudobulges; the former are considered to be end products of galactic mergers and the latter to form via secular evolution of galactic disks.
Okamoto, Takashi
core   +1 more source