Results 71 to 80 of about 77,216 (325)
An Inward-moving and Asymmetric Velocity Wave Detected in LAMOST-Gaia
The Astrophysical Journal LettersThe phase space, as coded by kinematic parameters and chemical abundances, is crucial for understanding the formation of the Galactic disk. Using red giant stars from the Galactic thin disk with [Fe/H] > − 0.8 and low- α ratios identified in LAMOST-Gaia,
Yuqin Chen +5 more
doaj +1 more source
The Gaia-ESO Survey: Chemical evolution of Mg and Al in the Milky Way with machine learning [PDF]
, 2023 M. Ambrosch +17 more
openalex +1 more source
Evolution of the Milky Way halo by accretion of dwarf satellite galaxies
, 2011 Within the Cold Dark Matter scenario the hierarchical merging paradigm is the natural result to form massive galactic halos by the minor mergers of sub-halos and, by this, inherently their stellar halo.
Bouchard +9 more
core +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
The Extremely Metal-rich Knot of Stars at the Heart of the Galaxy
The Astrophysical JournalWe show with Gaia XP spectroscopy that extremely metal-rich (EMR) stars in the Milky Way ([M/H] _XP ≳ 0.5) are largely confined to a tight “knot” at the center of the Galaxy. This EMR knot is round in projection, has a fairly abrupt edge near R _GC,proj ∼
Hans-Walter Rix +17 more
doaj +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
The Astrophysical JournalThe Milky Way (MW) is a barred spiral galaxy shaped by tidal interactions with its satellites. The Large Magellanic Cloud (LMC) and the Sagittarius dwarf galaxy (Sgr) are the dominant influences at the present day. This paper presents a suite of four 10 ^
Ioana A. Stelea +2 more
doaj +1 more source
Cosmological pseudobulge formation
, 2012 Bulges can be classified into classical and pseudobulges; the former are considered to be end products of galactic mergers and the latter to form via secular evolution of galactic disks.
Okamoto, Takashi
core +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
What Is Missing from the Local Stellar Halo?
The Astrophysical JournalThe Milky Way’s stellar halo, which extends to >100 kpc, encodes the evolutionary history of our Galaxy. However, most studies of the halo to date have been limited to within a few kiloparsecs of the Sun.
Katherine Sharpe +2 more
doaj +1 more source