Results 81 to 90 of about 320,090 (320)
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
The Astrophysical JournalThe Milky Way (MW) is a barred spiral galaxy shaped by tidal interactions with its satellites. The Large Magellanic Cloud (LMC) and the Sagittarius dwarf galaxy (Sgr) are the dominant influences at the present day. This paper presents a suite of four 10 ^
Ioana A. Stelea +2 more
doaj +1 more source
Chemodynamics of the Milky Way and disc formation history: insight from the RAVE and Gaia-ESO surveys [PDF]
, 2016 Multi-object spectrographs have opened a new window on the analyses of the chemo-dynamical properties of old Milky Way stars. These analyses allow us to trace back the internal mechanisms and the external factors that have influenced the evolution of our Galaxy, and therefore understand fundamental aspects of galaxy evolution in general.
arxiv +1 more source
Nova contributions to the chemical evolution of the Milky Way [PDF]
Astronomy & AstrophysicsContext. The explosive burning that drives nova eruptions results in unique nucleosynthesis that heavily over-produces certain isotopes relative to the solar abundance. However, novae are often ignored when considering the chemical evolution of our Galaxy due to their low ejecta masses.
Alex J. Kemp +5 more
openaire +2 more sources
A potential tumor suppressor role of PLK2 in glioblastoma
FEBS Open Bio, EarlyView.PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia +5 more
wiley +1 more source
What Is Missing from the Local Stellar Halo?
The Astrophysical JournalThe Milky Way’s stellar halo, which extends to >100 kpc, encodes the evolutionary history of our Galaxy. However, most studies of the halo to date have been limited to within a few kiloparsecs of the Sun.
Katherine Sharpe +2 more
doaj +1 more source
The Galactic Interstellar Object Population: A Framework for Prediction and Inference
The Astronomical Journal, 2023 The Milky Way is thought to host a huge population of interstellar objects (ISOs), numbering approximately 10 ^15 pc ^−3 around the Sun, which are formed and shaped by a diverse set of processes ranging from planet formation to Galactic dynamics.
Matthew J. Hopkins +4 more
doaj +1 more source
Life in the fast lane: a direct view of the dynamics, formation, and evolution of the Milky Way's bar [PDF]
, 2019 Studies of the ages, abundances, and motions of individual stars in the Milky Way provide one of the best ways to study the evolution of disk galaxies over cosmic time. The formation of the Milky Way's barred inner region in particular is a crucial piece of the puzzle of disk galaxy evolution.
arxiv +1 more source
The early phases of Milky Way's chemical evolution [PDF]
Nuclear Physics A, 2005 10 pages, 4 figures, Review talk in Nuclei in the Cosmos VIII (Eds. L.
openaire +3 more sources
FEBS Open Bio, EarlyView.This study reports the upregulation of ELMO1 and GPR141 in human Fuchs' endothelial corneal dystrophy (FECD) corneal endothelium and ultraviolet A‐induced FECD mice model. A genetic association of an intergenic single nucleotide polymorphism rs918980 present between both genes is observed with FECD in the Indian population.
Susmita Sharma +3 more
wiley +1 more source